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Masked Hypertension

Phenomenon where increased BLOOD PRESSURE readings taken in non-clinical settings (e.g., HOME BLOOD PRESSURE MONITORING) do not replicate in clinical settings.
Also Known As:
Hypertension, Masked; Hypertensions, Masked; Masked Hypertensions
Networked: 222 relevant articles (13 outcomes, 39 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Prehypertension
2. Kidney Diseases (Kidney Disease)
3. Hypertension (High Blood Pressure)
4. White Coat Hypertension
5. Obstructive Sleep Apnea

Experts

1. Shimbo, Daichi: 15 articles (08/2022 - 06/2012)
2. Kario, Kazuomi: 15 articles (01/2021 - 04/2007)
3. Muntner, Paul: 14 articles (08/2022 - 06/2013)
4. Schwartz, Joseph E: 11 articles (08/2022 - 08/2010)
5. Pickering, Thomas G: 10 articles (12/2016 - 08/2007)
6. Imai, Yutaka: 9 articles (01/2014 - 08/2005)
7. Yano, Yuichiro: 8 articles (10/2022 - 04/2009)
8. Ohkubo, Takayoshi: 8 articles (08/2013 - 08/2005)
9. Hoshide, Satoshi: 7 articles (01/2020 - 04/2007)
10. Ogedegbe, Gbenga: 7 articles (06/2017 - 05/2008)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Masked Hypertension:
1. 4- (2- (4- hydroxybenzyl)- phenoxy)- N- methylbutylamineIBA
2. Antihypertensive Agents (Antihypertensives)IBA
12/01/2022 - "Antihypertensive treatment in masked hypertension for target organ protection (ANTI-MASK): a randomized, double-blind, placebo-controlled trial."
12/06/2016 - "Between 2005 and 2012, 888 healthy, employed, middle-aged (mean±SD age, 45±10.4 years) individuals (59% female, 7.4% black, 12% Hispanic) with screening BP <160/105 mm Hg and not taking antihypertensive medication completed 3 separate clinic BP assessments and a 24-hour ABP recording for the Masked Hypertension Study. "
03/01/2015 - "A number of studies have shown that masked hypertension (MH) confers an increased risk of target organ damage and of cardiovascular events suggesting that patients with MH would benefit from antihypertensive treatment. "
04/01/2008 - "Prevalence of Masked Hypertension in Subjects Treated with Antihypertensive Drugs as Assessed by Morning versus Evening Home Blood Pressure Measurements: the J-HOME study."
01/01/2022 - "We restricted the analyses to participants with office systolic BP (SBP) <130 mm Hg and diastolic BP (DBP) <80 mm Hg. High awake BP was defined as mean SBP/DBP ≥130/80 mm Hg, high asleep BP as mean SBP/DBP ≥110/65 mm Hg, and high 24-hour BP as mean SBP/DBP ≥125/75 mm Hg. Among participants not taking antihypertensive medication (n = 1,292), the prevalence of masked hypertension with out-of-office BP defined by awake BP alone or by awake, asleep, or 24-hour BP was 34.5% and 48.7%, respectively, among non-Hispanic White, 39.7% and 67.6% among non-Hispanic Black, and 19.4% and 35.1% among Hispanic participants. "
3. Glucose (Dextrose)FDA LinkGeneric
08/01/2009 - "Over a 10-year period, the increase in plasma glucose and the incidence of new-onset diabetes (plasma glucose > or =126 mg/dl or use of antidiabetic drugs) was significantly greater in individuals with white-coat and masked hypertension than in those with 'true' normotension (age and sex-adjusted risk 2.9 and 2.7, respectively), the increase being similar to that of sustained hypertensive individuals. "
01/01/2021 - "In comparison with normotensive patients, patients with masked hypertension had longer duration of T1D (7.4 vs. 4.6 years, p = 0.049), higher insulin requirement (1.2 vs. 0.9 units/kg/day, p = 0.049), and higher SD of glucose (70.3 vs. 47.9 mg/dl, p = 0.038). "
08/01/2009 - "The adjusted risk showed a marked increase when development of an impaired fasting glucose condition was also considered, and the results were similar when individuals reporting antihypertensive drug treatment were excluded or white-coat and masked hypertension were identified by office versus home blood pressure. "
08/01/2010 - "Masked hypertension defined by 24-hour ambulatory BP is associated with an increased serum glucose level and urinary albumin-creatinine ratio, but these relationships are not observed in masked hypertension defined by HBP."
08/01/2010 - "Masked hypertension was defined as office BP < or =140/90 mm Hg and 24-hour ambulatory BP > or =130/80 mm Hg. The masked hypertensive participants defined by 24-hour ambulatory BP (n=13) had a higher serum glucose level (126 vs 96 mg/dL, P=.001) and urinary albumin-creatinine ratio (38.0 vs 7.5 mg/gCr, P<.001) than the normotensive participants (n=74); however, these relationships were not observed when the authors defined groups using HBP (> or =135/85 mm Hg). "
4. Hypoglycemic Agents (Hypoglycemics)IBA
5. mahuang-tangIBA
6. Retinaldehyde (Retinal)IBA
7. AlbuminsIBA
8. CreatinineIBA
9. Biomarkers (Surrogate Marker)IBA
10. SodiumIBA

Therapies and Procedures

1. Therapeutics
2. Kidney Transplantation
3. Ambulatory Care (Outpatient Care)
4. Precision Medicine
5. Drug Therapy (Chemotherapy)