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Vascular Diseases (Vascular Disease)

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Pathological processes involving any of the BLOOD VESSELS in the cardiac or peripheral circulation. They include diseases of ARTERIES; VEINS; and rest of the vasculature system in the body.

Also Known As:

Vascular Disease; Disease, Vascular; Diseases, Vascular

Networked: 8888 relevant articles (300 outcomes, 934 trials/studies) for this Disease, Comments

Relationship Network

Disease Context: Research Results

Cardiovascular Diseases: 28068
- Vascular Diseases: 8888

Related Diseases

1.	Atherosclerosis
2.	Stroke (Strokes)
3.	Hypertension (High Blood Pressure)
4.	Myocardial Infarction
5.	Cardiovascular Diseases (Cardiovascular Disease)

Experts

1.	Mikhailidis, Dimitri P: 11 articles (11/2012 - 01/2003)
2.	Nilsson, Karin: 11 articles (04/2012 - 01/2005)
3.	Hultberg, Björn: 11 articles (04/2012 - 01/2005)
4.	Gustafson, Lars: 11 articles (04/2012 - 01/2005)
5.	Yusuf, Salim: 11 articles (09/2011 - 03/2002)
6.	Channon, Keith M: 10 articles (04/2012 - 03/2004)
7.	Matsuzawa, Yuji: 10 articles (04/2008 - 04/2002)
8.	Mikhailidis, D P: 9 articles (06/2012 - 01/2000)
9.	Sattar, Naveed: 9 articles (01/2012 - 12/2004)
10.	Lip, Gregory Y H: 9 articles (01/2012 - 06/2004)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Vascular Diseases:

1.	CollagenIBA 01/01/2012 - "Although chest radiography is most often used for screening and monitoring of thoracic alterations, high-resolution computed tomography can provide additional information about lung involvement in collagen vascular diseases and may be especially helpful for differentiating specific disease patterns in the lung. " 12/01/1979 - "Treatment of the underlying collagen-vascular disease improved the eruption, while recurrence coincided with exacerbation of the systemic disease. " 11/01/2011 - "Future studies will be necessary to clarify the use of PBI in patients with collagen vascular disease." 06/01/2010 - "In this study, high-dose GC use was associated with a significantly high prevalence of symptomatic vertebral fractures in premenopausal women with collagen vascular disease during their childbearing years. " 07/01/2009 - "Serologic study for viral agents and collagen vascular disease were negative in all patients with renal involvements. " Order ALL the reference details at left...
2.	Aspirin (Acetylsalicylic Acid)FDA LinkGeneric 01/01/2006 - "Forty two percent of patients were regular aspirin users, and were comparable to the non aspirin group, apart from having a significantly greater prevalence of atherosclerotic vascular disease. " 01/01/2005 - "Aspirin reduces the risk of thrombotic events in a broad range of patients with vascular disease and, in selected individuals, is beneficial for primary prevention. " 10/01/1994 - "Although both high- and low-dose aspirin therapies are effective for secondary prophylaxis in patients with atherosclerotic vascular disease, the acute response to low-dose aspirin therapy is controversial. " 11/01/2010 - "Aspirin is effective for the prevention of cardiovascular events in patients with a history of vascular disease, as so-called secondary prevention. " 12/01/2011 - "The MAGIC Study and the gastrointestinal effects of low-dose aspirin : editorial to: "Prospective cohort study of gastrointestinal complications and vascular diseases in patients taking aspirin: rationale and design of the MAGIC Study" by H. " Order ALL the reference details at left...
3.	CholesterolIBA 03/01/2011 - "Vascular disease: cholesterol-efflux capacity might be the key to the protective effects of HDL." 01/01/1998 - "Diet changes that lower fat, saturated fat, and cholesterol intake in children and adolescents can be applied safely and acceptably, resulting in improved plasma lipid profiles that, if carried into adult life have the potential to reduce atherosclerotic vascular disease." 02/01/2010 - "Predicted effects of 5 mmHg reductions in mean systolic blood pressures and 0.5 mmol l(-1) reductions in mean total blood cholesterol concentrations on deaths and years of life lost (YLL) per 100,000 person-years from vascular diseases were modelled using proportional risk coefficients from meta-analyses of cohort studies and randomized controlled trials. " 09/01/2009 - "Therefore, the aim of this study was to investigate differences in cholesterol metabolism in relation to vascular diseases in this subset of patients. " 11/01/2007 - "We argue that evaluating the importance of cholesterol for vascular disease risk in dialysis patients can only be achieved through the eradication of confounding by randomization, and that ongoing trials of cholesterol-lowering therapy will provide a definitive answer to this question." Order ALL the reference details at left...
4.	HomocysteineIBA 11/01/2000 - "However, the evidence needs to be strengthened by a systematic review of all comparable studies and the demonstration, in randomised trials, that lowering total homocysteine is followed by a significant reduction in atherothrombotic vascular disease. " 10/01/2004 - "Homocysteine is a risk factor for vascular diseases, and lowering of plasma total homocysteine (tHcy) may be beneficial for health. " 05/01/2000 - "To date, no randomized clinical trial has demonstrated that lowering of homocysteine levels is beneficial in terms of reducing the prevalence of vascular disease. " 02/01/1990 - "These data show that a substantial proportion of patients with early-onset vascular disease have impaired homocysteine metabolism, which may contribute to vascular disease, and that the impaired metabolism can be improved easily and without side effects." 02/01/2011 - "This review is based on a meta-analysis of published results of eight homocysteine-lowering trials for preventing vascular disease. " Order ALL the reference details at left...
5.	Retinaldehyde (Retinal)IBA 01/01/2012 - "Improved knowledge of these features may be important for understanding pathogenic mechanisms underlying retinal vascular diseases." 12/01/2012 - "The proposed method aims to restore the topology of the vascular trees with anatomical realism for clinical studies and diagnosis of retinal vascular diseases, which manifest abnormalities in either venous and/or arterial vascular systems. " 01/01/2012 - "The results obtained from the present studies may help our understanding the pathogenesis of the retinal vascular disease associated with high levels of CRP." 02/01/2011 - "Eyes with retinal vascular diseases and inflammatory diseases were excluded from the study. " 05/15/2010 - "The present study tested the hypothesis that glial dysfunction is a major contributor to the BRB breakdown that is a hallmark of retinal vascular diseases. " Order ALL the reference details at left...
6.	Angiotensin-Converting Enzyme Inhibitors (ACE Inhibitors)IBA 04/01/2011 - "Results of the main randomized clinical trials that evaluated the benefit of ACE inhibitors in patients with vascular disease are discussed in this editorial. " 05/01/2010 - "Some studies have also demonstrated the statistical equivalence of ARBs to ACE inhibitors in certain populations (e.g., among post-MI patients in VALIANT and among a broad population of patients with vascular disease or diabetes in the ONTARGET). " 04/01/2005 - "ACE inhibitors in patients with vascular disease: should the PEACE trial change medical practice?" 02/01/2002 - "A large body of experimental evidence reporting that ACE inhibitors limit these effects has formed the rationale for major clinical trials of these drugs in the management of atherosclerotic vascular disease. " 11/21/2001 - "Recent trials of ACE inhibitors in patients with vascular disease who do not have the traditional indications for ACE inhibition have shown a reversal of endothelial dysfunction and a reduction in adverse clinical endpoints. " Order ALL the reference details at left...
7.	Platelet Aggregation Inhibitors (Antiplatelet Drugs)IBA 12/01/2004 - "Antiplatelet agents are effective in preventing recurrence of vascular events among patients with established vascular disease or with multiple risk factors. " 10/20/2004 - "Antiplatelet agents, used alone or in combination, are effective in preventing recurrent vascular events among individuals with established vascular disease. " 01/01/1985 - "We conclude that this study should provide definitive data on the efficacy of these antiplatelet agents in preventing further vascular disease in this patient group. " 12/01/2011 - "Sophisticated imaging protocols have minimized the need for invasive methods, and the efficacy of medical therapy (with newer antiplatelet agents and statins) has improved outcomes related to vascular disease. " 09/01/1999 - "New antiplatelet drugs are being developed and many clinical trials evaluating the benefits of antiplatelet drugs for the secondary prevention of ischemic events in patients with atherosclerotic vascular disease have been performed. " Order ALL the reference details at left...
8.	Lipoproteins (Lipoprotein)IBA 01/17/2000 - "Elevated levels of plasma high density lipoprotein (HDL) are strongly predictive of protection against atherosclerotic vascular disease. " 12/01/2009 - "Finally competing risk, conditioning the timing and occurrence of vascular events in our study population, could be a correct approach for evaluating the role of Lp(a) lipoprotein in vascular disease among elderly people." 12/01/2005 - "Despite this evidence and the national clinical guidelines recommending lipid-lowering treatment and low-density lipoprotein (LDL) goal attainment in patients with clinically evident atherosclerotic vascular disease or similar risk, study after study has documented low treatment rates. " 04/15/2004 - "In OC and HRT users, this leads to a range of different lipoprotein profiles, which may differ from those evaluated with respect to vascular disease risk in population studies. " 06/01/2012 - "Associations of gender, age, lipoproteins, blood pressure, BMI z-score, waist:height ratio and parental history of early vascular disease, with extra-medial thickness were examined. " Order ALL the reference details at left...
9.	clopidogrel (Plavix)FDA Link 08/15/2004 - "Clopidogrel is superior to ASA in patients with high risk of recurrence due to concomitant vascular disease or multiple risk factors. " 03/01/2002 - "These results demonstrated that long-term administration of clopidogrel was effective in preventing ischaemic events in patients with atherosclerotic vascular disease including PAD. " 05/01/2008 - "Clinical trials have helped clarify the efficacy of clopidogrel for the treatment and prevention of vascular disease. " 05/02/2007 - "Large multi-center clinical trials have indicated significant clinical benefits for patients with atherosclerotic vascular diseases receiving clopidogrel therapy. " 10/30/2012 - "An evaluation was conducted of health care spending and resource use by a large self-insured employer that reduced statin copayments for patients with diabetes or vascular disease and reduced clopidogrel copayments for all patients prescribed this drug. " Order ALL the reference details at left...
10.	Folic Acid (Vitamin M)FDA LinkGeneric 10/01/2002 - "Increasing natural folate intake improved folate status and decreased tHcy concentrations to an extent that may significantly reduce the risk of vascular disease. " 05/01/2011 - "Randomized controlled trials in vascular patients have failed to show that folic acid reduces the risk of recurrent vascular disease, whereas such trials are lacking in the general population. " 02/01/2004 - "The potential beneficial role of folic acid supplements on vascular disease are currently being tested in randomized placebo controlled studies." 04/09/1998 - "Further clinical trials are required to determine whether folic acid fortification may prevent vascular disease. " 05/01/2012 - "Hence, large-scale corrective measures like food fortification or dietary supplementation with folate might benefit the Indian population and reduce the incidence and morbidity of vascular disease." Order ALL the reference details at left...

Therapies and Procedures

1.	Transplants (Transplant) 03/11/1982 - "We hope that such transplants may ultimately provide an improved outlook for selected terminally ill patients with pulmonary vascular disease and certain other intractable cardiopulmonary disorders." 03/01/2011 - "This review describes the mainly in vitro and in vivo studies used to define the molecular role hemodynamics have in vascular disease and its usage in developing tissue engineered vascular bypass grafts." 10/01/2005 - "This retrospective, autopsy-based study examined 27 heart transplant patients to evaluate for graft vascular disease. " 09/01/2002 - "His interest was directed to the maturation of endocardial stimulation threshold; use of non-atrial sensors in the frequent adaptation of a permanent artificial conductor of cardiac rhythm-pacemaker to load; use of continuous electrostimulation of spinal cord in patients in terminal state of vasospastic and occlusive vascular diseases; study of the effort of electromagnetic fields on pacemaker inhibition and senzation; study of biologic-synthetic grafts. " 06/01/1997 - "To study the frequency and determinants if vascular disease in Sri Lankan patients with renal transplants. " Order ALL the reference details at left...
2.	Transplantation (Transplant Recipients) 01/01/1994 - "In humans, the cerebral cortex can be affected by a variety of diseases (vascular, traumatic, neurodegenerative, etc.) and, therefore, several experimental studies have been undertaken to determine to what extent transplantation of cortical neurons could prove a useful treatment for cerebral cortical damage. " 03/01/2010 - "Despite improved medical therapy, transplantation (Tx) represents the only option for end-stage pulmonary vascular disease. " 01/01/2012 - "Orthotopic aortic transplantation in mice for the study of vascular disease." 09/01/2008 - "This study was designed to address characteristics of extracoronary vascular disease in heart transplant recipients. " 03/01/2011 - "Transplantation of mesenchymal stromal cells (MSC), including adipose tissue-derived stem cells (ASC), is a promising option in the treatment of vascular disease. " Order ALL the reference details at left...
3.	Stents 05/04/2010 - "The use of stents for vascular disease has resulted in a paradigm shift with significant improvement in therapeutic outcomes. " 04/01/2002 - "Vascular stents have emerged as an effective treatment for occlusive vascular disease. " 12/05/2005 - "Other animal studies have shown that vascular stents used to relieve arterial obstruction can also be used as gene delivery systems to provide therapeutic vector constructs that can both locally prevent post stenting reobstruction, known as in-stent restenosis, and treat the underlying vascular disease. " 02/01/2005 - "With the recent advances in renal artery stent revascularization, a procedure that can be accomplished with <1% major complication rate, 90-95% success rate and 10-15% restenosis rate, multiple studies have reported the salutary hemodynamic benefits and increased awareness of prevalence of RAS in patients with vascular disease. " 04/24/2012 - "The use of endovascular stents are a common clinical intervention for the treatment of arteries occluded due to vascular disease. " Order ALL the reference details at left...
4.	Amputation 06/01/2011 - "The study comprised 28 individuals (20 males, eight females, mean age 49 years) with a unilateral amputation due to reasons other than vascular disease and 31 healthy volunteers (20 males, 11 females, mean age 47 years). " 04/01/2010 - "The results of this study help to understand the challenge of every-day live after a lower limb amputation caused by vascular diseases, which should serve for a basis of support for these people." 04/01/2010 - "This study examines how people with a lower-limb amputation caused by vascular diseases experience and manage their every-day life. " 01/01/2010 - "The aim of this study was to describe leisure activities, leisure satisfaction and constraints on participation in leisure following a unilateral lower limb amputation due to vascular disease. " 02/01/2004 - "To study the activity level and heart rate response, objectively measured during normal daily life, of persons with a unilateral transtibial amputation for vascular disease. " Order ALL the reference details at left...
5.	Catheters 11/29/2012 - "Because both parameters can only be derived from invasive hemodynamic assessment, right heart catheter (RHC) is still a gold standard for the diagnosis of PH. Severe precapillary PH corresponds to pulmonary vascular disease and carries a poor prognosis. " 12/01/2004 - "Although catheter angiography, or digital subtraction angiography (DSA), is still regarded as the gold standard for imaging of cervicocranial vascular disease, its morbidity, cost, and time-consuming features have prompted the development of noninvasive techniques based on computed tomography (CT) and magnetic resonance imaging. " 07/01/1999 - "The aim of this study was to determine whether morphological changes in vessels accessible to intravascular imaging reflect severity of pulmonary vascular disease and are of a sufficient degree to be detectable by current ultrasound catheters. " 01/01/1992 - "These studies demonstrate that this technique can provide high resolution images of arterial vessels and may have unique advantages in diagnosing atherosclerotic vascular disease and in catheter based therapies." 07/01/2012 - "Surgical closure or catheter-delivered devices is recommended in all patients with APW and should be performed after diagnosis as soon as possible to prevent irreversible pulmonary vascular disease. " Order ALL the reference details at left...

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