Blood-Borne Infections

Diseases due to or propagated by body fluids from hosts whose BLOOD has been contaminated with pathogens.

Also Known As:

Blood Borne Disease; Blood Borne Infection; Blood-Borne Infection; Disease, Blood Borne; Infection, Blood Borne; Infection, Blood-Borne; Blood Borne Diseases; Blood Borne Infections

Networked: 257 relevant articles (13 outcomes, 10 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1.	Hemorrhage
2.	Infections
3.	Hepatitis
4.	Acquired Immunodeficiency Syndrome (AIDS)
5.	Wounds and Injuries (Trauma)

Experts

1.	Strathdee, Steffanie A: 10 articles (12/2018 - 04/2002)
2.	Lozada, Remedios: 4 articles (08/2012 - 07/2009)
3.	Noroozi, Alireza: 3 articles (02/2019 - 02/2013)
4.	Garfein, Richard S: 3 articles (12/2018 - 01/2007)
5.	Magis-Rodríguez, Carlos: 3 articles (12/2018 - 09/2005)
6.	Werb, Dan: 3 articles (12/2018 - 12/2013)
7.	Pollini, Robin A: 3 articles (01/2017 - 07/2009)
8.	Wood, Evan: 3 articles (12/2013 - 08/2005)
9.	Brouwer, Kimberly C: 3 articles (02/2012 - 09/2005)
10.	de la Fuente, Luis: 2 articles (01/2021 - 01/2011)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Blood-Borne Infections:

1.	Deamino Arginine Vasopressin (Desmopressin)FDA LinkGeneric 01/01/1987 - "At this time, when the acquired immunodeficiency syndrome, hepatitis, and other blood-borne diseases threaten patients, with bleeding disorders, who need treatment with blood products, it is rewarding to realize that a number of them can be safely and effectively treated through the stimulation of their own VIII:C and vWF production with desmopressin. " 01/01/1986 - "At a time when the acquired immunodeficiency syndrome as well as hepatitis and other blood-borne diseases are a threat to patients with bleeding disorders who need treatment with blood products, it is rewarding to realize that a number of these patients can be safely and effectively treated with their own desmopressin-stimulated F.VIII:C and vWF. "
2.	VaccinesIBA 01/01/1998 - "Vaccination with HBV vaccine and application of universal precautions during daily practice seem to be the only and most effective means of protection against blood-borne infections." 04/01/2004 - "A particular problem is that the majority of vaccines currently used are injected, which can be unsafe if needles are reused in areas where blood-borne diseases are prevalent. " 01/01/2000 - "Needle free jet injection guns have been used extensively in both veterinary and human health to deliver both vaccine and drugs, but in recent years, concerns have mounted for their potential to transmit blood borne disease agents among consecutive vaccinates. " 01/01/2000 - "While further study is needed to elucidate the biology of HCV transmission and develop vaccines for prevention, new HCV infections can be reduced by economic development and education regarding blood-borne infections." 04/01/2010 - "Mucosal immunity elicited by plant-based and other orally administered vaccines can serve as the first line of defense against most pathogens infecting through mucosal surfaces, but it is also considered for systemic immunity against blood-borne diseases such as hepatitis B (HB). "
3.	Illicit Drugs (Recreational Drugs)IBA 09/01/2005 - "Historical trends in the production and consumption of illicit drugs in Mexico: implications for the prevention of blood borne infections." 11/21/2003 - "By assisting illicit drug injectors to obtain sterile syringes the primary care provider is able to reduce the incidence of blood borne infections, and educate patients about safe syringe disposal. " 08/01/2001 - "Illicit drug use is also increasing, particularly injection drug use, followed by an epidemic spread of HIV and other blood-borne infections. " 01/01/2015 - "Illicit drug use in the US remains concerning, with injection drug use linked to transmission of blood-borne diseases as HIV/AIDS; persons of color, including Black Americans, experience disproportionately higher transmission rates. " 09/01/2010 - "Experiences in Iran suggest that access to MMT would be helpful for reducing illicit drug injection in a prison setting and can be considered as a major intervention for preventing the transmission of blood-borne infections among prisoners."
4.	Factor VIII (Coagulation Factor VIII)IBA 03/01/2014 - "Recombinant factor VIII inception has decreased the risk of blood borne infections and restored back longer life expectancies. " 01/01/1987 - "Current factor VIII products expose recipients to many donors and hence to a high risk of acquiring blood-borne infections. " 01/01/1990 - "The last few paragraphs will summarize pertinent characteristics of this material in relation to other current sources of factor VIII. First, at a time when safety is the paramount concern in hemophilia therapy, plasma exchange donation offers a product with a very low intrinsic risk of blood borne infection; in many cases, this risk can be equivalent to a single unit of blood. " 01/01/1996 - "Recombinant factor VIIa (rFVIIa) improves haemostasis and eliminates the risk of transmission of blood-borne infection in haemophilia patients with inhibitors, acquired inhibitors to factor VIII or IX or FVII deficiency. " 01/01/1986 - "At a time when the acquired immunodeficiency syndrome as well as hepatitis and other blood-borne diseases are a threat to patients with bleeding disorders who need treatment with blood products, it is rewarding to realize that a number of these patients can be safely and effectively treated with their own desmopressin-stimulated F.VIII:C and vWF. "
5.	Methadone (Dolophine)FDA LinkGeneric 07/01/2008 - "We examined the impact of methadone maintenance treatment (MMT) on risk behaviors for transmission of blood-borne diseases in polydrug users who had tested positive or negative for hepatitis C virus (HCV). " 05/01/2012 - "Hepatitis C virus (HCV) is a prevalent chronic blood-borne infection among opioid-dependent patients on methadone maintenance treatment (MMT). " 11/01/2010 - "Methadone used in conjunction with other harm reduction initiatives can reduce the transmission of blood-borne infections among individuals who inject opiates, however many who enter the BC Methadone Program are already anti-HCV positive and others seroconvert after MMT initiation. " 09/10/2016 - "Effective treatment of opioid use disorders with opioid agonist therapies (eg, methadone and buprenorphine) prevents blood-borne infections via reductions in injection in prison and after release. "
6.	2-methylcyclopentadienyl manganese tricarbonyl (MMT)IBA 09/01/2010 - "Experiences in Iran suggest that access to MMT would be helpful for reducing illicit drug injection in a prison setting and can be considered as a major intervention for preventing the transmission of blood-borne infections among prisoners." 07/01/2008 - "We examined the impact of methadone maintenance treatment (MMT) on risk behaviors for transmission of blood-borne diseases in polydrug users who had tested positive or negative for hepatitis C virus (HCV). " 05/01/2012 - "Hepatitis C virus (HCV) is a prevalent chronic blood-borne infection among opioid-dependent patients on methadone maintenance treatment (MMT). " 11/01/2010 - "Methadone used in conjunction with other harm reduction initiatives can reduce the transmission of blood-borne infections among individuals who inject opiates, however many who enter the BC Methadone Program are already anti-HCV positive and others seroconvert after MMT initiation. "
7.	Opioid Analgesics (Opioids)IBA 07/01/2013 - "Positive outcomes associated with opioid substitution treatment include reduced illicit opioid use and lower risk of HIV and other blood-borne infections. " 05/01/2012 - "Hepatitis C virus (HCV) is a prevalent chronic blood-borne infection among opioid-dependent patients on methadone maintenance treatment (MMT). " 09/10/2016 - "Effective treatment of opioid use disorders with opioid agonist therapies (eg, methadone and buprenorphine) prevents blood-borne infections via reductions in injection in prison and after release. "
8.	Intravenous Immunoglobulins (IVIG)FDA Link 08/01/2010 - "Newer manufacturing processes have increased the yield of intact IVIg molecules and have also improved the tolerability and safety of these products, including reducing the transmission risk of blood-borne diseases. "
9.	Buprenorphine (Subutex)FDA LinkGeneric 09/10/2016 - "Effective treatment of opioid use disorders with opioid agonist therapies (eg, methadone and buprenorphine) prevents blood-borne infections via reductions in injection in prison and after release. "
10.	AllergensIBA 12/01/2003 - "Continuous glove use is more common in dentistry than in most other occupations, and the glove should offer protection against blood-borne infections, skin irritants and contact allergens. "

Therapies and Procedures

1.	Sutures (Suture) 11/01/2003 - "Efforts to prevent surgeon-to-patient transmission of blood-borne infections should focus not only on ascertaining the infection status of the HCW but principally on eliminating the cause of blood-borne exposures, for example by the use of blunt suture needles, improved instruments, reinforced gloves, changes in surgical technique and the use of less invasive alternative procedures. " 01/01/2018 - "Sutures remain as the "gold standard" for wound closure and bleeding control; however they still have limitations such as, high infection rate, inconvenience in handling, and concern over possible transmission of blood-borne disease through the use of needles. " 01/01/2003 - "However, discomfort at the time of suture removal, particularly in children, and the risk of transmission of blood-borne infections in gels are limitations to these wound closure techniques. "
2.	Blood Transfusion (Blood Transfusions) 08/28/2012 - "This study reflects the risk of TTIs has been greatly reduced in China, but blood transfusion remains an ongoing risk factor for the spread of blood-borne infections, and further work and improvements are needed to strengthen both safety and availability of blood in China." 09/01/2020 - "Some patients who need surgery refuse a blood transfusion because of their religious beliefs or concerns about blood-borne infections. " 09/01/2019 - "Despite blood transfusion being a lifesaving option, it may be associated with blood borne infections including human cytomegalovirus(HCMV). " 01/01/2019 - "Multiple blood transfusions increase the risk of transmitting blood-borne infections. " 11/01/2018 - "Blood transfusion after kidney transplant carries a risk of sensitization to the graft as well as blood borne infections. "
3.	Therapeutics 04/01/2013 - "This study stresses on the need for a continued screening and surveillance in the routine blood culture technique for starting with the empiric therapy for blood borne infections." 08/04/2016 - "Acupuncture, used in China for over 2,500 years, has been gaining popularity as an alternative medical therapy in the western world, but when associated with poor infection control practices, is also a risk for blood-borne infections. " 11/01/2013 - "Our data highlights that delay in diagnosis and blood-borne infections were significantly reduced over the decade, but the development of inhibitor still remains a major challenge with wide-scale usage of factor in replacement therapy." 03/01/1994 - "Combined with continuous education of blood therapy prescribers, this may lead to a reduction of unnecessary transfusions and to the subsequent reduction of blood-borne disease transmission in Maputo." 12/01/1990 - "Recently, several factors, including the awareness of associated risks, especially the transmission of blood-borne diseases and the transient treatment effect with regard to reversal of anemic symptoms, have caused a reassessment of transfusion therapy. "
4.	Autologous Blood Transfusion 08/06/1994 - "The risk of blood-borne diseases has substantially increased the use of autologous blood transfusion. " 01/01/2021 - "Although autotransfusion can avoid blood-borne diseases and adverse reactions related to allogeneic blood transfusion, a series of structural and functional changes of erythrocytes will occur during extension of storage time, thus affecting the efficacy of clinical blood transfusion. " 12/01/1988 - "Advantages of autotransfusion over banked blood include avoidance of alloimmunization, reduction of transfusion reactions and blood-borne infections, less expense, and acceptance by most religious groups. " 04/01/1987 - "By eliminating the need for any bank blood components in most patients, rapid autotransfusion minimizes the risk of blood-borne diseases and transfusion reactions. "
5.	Donor Selection 09/01/2004 - "Although donor exclusion criteria ensure that the number of any further iatrogenic cases will be small, the risk of future blood-borne disease transmissions could be entirely eliminated by a diagnostic preclinical screening test. "