A derivative of the opioid alkaloid THEBAINE that is a more potent and longer lasting analgesic than MORPHINE. It appears to act as a partial agonist at mu and kappa opioid receptors and as an antagonist at delta receptors. The lack of delta-agonist activity has been suggested to account for the observation that buprenorphine tolerance may not develop with chronic use.
Also Known As:
Subutex; Buprenex; 6029-M; Buprenorphine Hydrochloride; Buprex; Prefin; RX-6029-M; Temgesic; Temgésic; 6029 M; 6029M; Hydrochloride, Buprenorphine; RX 6029 M; RX6029M; 6,14-Ethenomorphinan-7-methanol, 17-(cyclopropylmethyl)-alpha-(1,1-dimethylethyl)-4,5-epoxy-18,19-dihydro-3-hydroxy-6-methoxy-alpha-methyl-, (5alpha,7alpha(S))-