Coronavirus Receptors

A broad class of cell surface proteins that bind specifically to VIRAL SPIKE PROTEINS found on a CORONAVIRUS. The attachment of the virus is the first step of a process that leads to CORONAVIRUS INFECTIONS.

Also Known As:

Networked: 20 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Alipour, Shahriar: 1 article (06/2022)
2.	Asghari, Rahim: 1 article (06/2022)
3.	Khadem Ansari, Mohammad Hasan: 1 article (06/2022)
4.	Sodagar, Hadi: 1 article (06/2022)
5.	Cao, Gang: 1 article (01/2022)
6.	Cao, Xiaojian: 1 article (01/2022)
7.	Chen, Anjing: 1 article (01/2022)
8.	Deng, Lulu: 1 article (01/2022)
9.	Dong, Shuang: 1 article (01/2022)
10.	Li, Wentao: 1 article (01/2022)

Related Diseases

1.	COVID-19 01/01/2022 - "Our work explores for the first time the association of coronavirus receptors with GBM and suggests ANPEP and ENPEP as potential therapeutic targets of GBM irrespective of COVID-19." 01/01/2022 - "Furthermore, we identified 245 genes between COVID-19 and coronavirus receptors-correlated genes in GBM and performed a thorough analysis of their protein-protein interaction network, functional signaling pathway and molecular process. " 01/01/2021 - "Our results identify residue determinants that mediate coronavirus receptor usage and host range for application in SARS-CoV-2 and emerging coronavirus animal model development.IMPORTANCE SARS-CoV-2 (the causative agent of COVID-19) is a major public health threat and one of two related coronaviruses that have caused epidemics in modern history. " 01/01/2020 - "We find the gut as the putative hotspot of COVID-19, where a maturation correlated transcriptional signature is shared in small intestine enterocytes among coronavirus receptors (ACE2, DPP4, ANPEP). " 06/18/2022 - "Since ACE2 reduces the acute inflammatory effects in lung diseases and acts as a coronavirus receptor to invade the lung cells, this study investigates the relationship between miR-200c-3p and ACE2 expression in COVID -19 patients. "
2.	Lung Diseases (Lung Disease) 06/18/2022 - "Since ACE2 reduces the acute inflammatory effects in lung diseases and acts as a coronavirus receptor to invade the lung cells, this study investigates the relationship between miR-200c-3p and ACE2 expression in COVID -19 patients. "
3.	Infections 01/01/2023 - "Finally, enterocyte cells expressed almost all coronavirus entry factors, and PEDV infection caused significant upregulation of the coronavirus receptor ACE2 in enterocyte cells. " 01/01/2022 - "Notably, iSFA results suggested that the expression of coronavirus receptor genes tended to be downregulated after infection by another virus. " 01/01/2020 - "Thus, we profiled the immune response across multiple coronavirus receptor binding domains (RBDs), respiratory viruses, and SARS-CoV-2, to determine whether heterologous immunity to other CoV-RBDs or other infections influenced the evolution of the SARS-CoV-2 humoral immune response. " 10/01/2001 - "Thus, certain differences in glycosylation between coronavirus receptors from different species are critical determinants in the species specificity of infection." 01/01/1993 - "Dissemination of MHV4 (strain JHM) infection does not require specific coronavirus receptors."
4.	Neoplasms (Cancer) 11/01/2020 - "Here, the expression of five genes, known to encode coronavirus receptors/interactors (ACE2, TMPRSS2, CLEC4M, DPP4 and TMPRSS11D), was investigated in normal and cancer tissues, and their molecular relationships with clinical comorbidities were investigated. " 11/01/2020 - "The five coronavirus receptors are related to all main COVID-19 comorbidities and three show significantly different expression in cancer versus control tissues. " 01/01/2020 - "RNA-Seq data from The Cancer Genome Atlas (TCGA) and GTeX databases were used for extensive profiling analysis of these receptors across 9,736 tumors and 8,587 normal tissues comparing coronavirus receptors. " 01/01/2020 - "Method: We took a bioinformatics approach to analyze the gene and protein expression data of these coronavirus receptors (DPP4, ANPEP, ENPEP, TMPRSS2) in human normal and cancer tissues of multiple organs including the brain, liver, kidney, heart, lung, skin, GI tract, pancreas, endocrine tissues, and the reproductive organs. "
5.	Coronavirus Infections 01/01/2023 - "S protein mediates coronavirus receptor binding and membrane fusion, and the latter activity can greatly influence coronavirus infection. "

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