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Membrane Proteins (Integral Membrane Proteins)

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Proteins which are found in membranes including cellular and intracellular membranes. They consist of two types, peripheral and integral proteins. They include most membrane-associated enzymes, antigenic proteins, transport proteins, and drug, hormone, and lectin receptors.

Also Known As:

Integral Membrane Proteins; Membrane Protein; Integral Membrane Protein; Protein, Membrane; Proteins, Membrane; Membrane Protein, Integral; Protein, Integral Membrane; Surface Proteins; Membrane-Associated Proteins; Membrane Associated Proteins; Membrane Proteins, Integral; Proteins, Cell Membrane; Proteins, Cell Surface; Proteins, Integral Membrane; Proteins, Membrane-Associated; Proteins, Surface; Cell Membrane Proteins; Cell Surface Proteins

Networked: 4679 relevant articles (107 outcomes, 309 trials/studies) for this Bio-Agent, Comments

Relationship Network

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins
- Proteins: 72216
  - Membrane Proteins: 4679

Experts

1.	Cao, Ya: 10 articles (06/2012 - 07/2003)
2.	Longnecker, Richard: 8 articles (03/2010 - 02/2002)
3.	Pagano, Joseph S: 6 articles (11/2012 - 11/2002)
4.	Schneewind, Olaf: 6 articles (01/2010 - 02/2002)
5.	de la Maza, Luis M: 6 articles (10/2009 - 09/2002)
6.	Raab-Traub, Nancy: 5 articles (10/2012 - 12/2002)
7.	Tang, Min: 5 articles (06/2012 - 07/2004)
8.	Stevenson, Brian: 5 articles (02/2012 - 02/2002)
9.	Brayton, Kelly A: 5 articles (01/2012 - 03/2002)
10.	Yoshizaki, Tomokazu: 5 articles (11/2011 - 11/2002)

Related Diseases

1.	Infection 05/01/2001 - "These variations in structure of an expression site for a major, immunoprotective outer membrane protein have important implications for vaccine development and for obtaining an improved understanding of the mechanisms of persistence of ehrlichial infections in humans, domestic animals, and reservoir hosts." 06/15/2009 - "Recent studies have shown immunization with Chlamydia muridarum major outer membrane protein (MOMP) can induce significant protection against infection and disease in mice if its native trimeric structure is preserved (nMOMP). " 09/01/1986 - "Although preparations containing lipopolysaccharide (LPS) and outer membrane proteins (OMP) from several strains gave protection against a non-toxigenic strain (FnB-3), they did not significantly immunize mice against a challenge infection with a toxigenic bovine strain, FnB-1. " 08/01/2010 - "trachomatis serovar E major outer membrane protein gene (Ad-MOMP), and investigated their ability to induce specific protection against genital tract chlamydial challenge infection. " 07/12/2010 - "We examined the induction of immunity following intranasal immunisation with major outer membrane protein (MOMP) of Chlamydia muridarum in male BALB/c mice, and the role of MOMP-specific CD4+ T cells in clearance of an intrapenile infection. " Order ALL the reference details at left...
2.	Neoplasms (Cancer) 03/28/2008 - "Overall, these findings provide insight into improved tumor vaccination strategies relying on the intratumoral expression of viral fusogenic membrane proteins." 03/28/2008 - "To promote the development of improved tumor vaccination strategies relying on the intratumoral expression of viral fusogenic membrane proteins, we elucidated whether the size of syncytia or the way tumor cells die has an effect on the therapeutic outcome. " 07/01/2011 - "Gene profiling reveals cancer specific signatures and may identify membrane proteins that are related to cancer progression and lead to the development of improved therapy strategies in the future." 01/01/2012 - "Membrane association of the PTEN tumor suppressor: molecular details of the protein-membrane complex from SPR binding studies and neutron reflection." 01/01/2010 - "The present study addresses this problem from a transcriptional standpoint, analyzing the expression of membrane protein genes--the Membranome--in primary tumors and immortalized in-vitro cultured tumor cells. " Order ALL the reference details at left...
3.	Malaria 08/01/2011 - "High antibody levels directed to Plasmodium falciparum merozoite surface proteins (MSP), including MSP2, as well as genetically related red blood cell defects, have previously been found to be associated with protection against malaria. " 05/15/2011 - "Additional identification of hemichromes associated with membrane proteins also supports a role for specific oxidative modifications in protection against malaria by G6PD polymorphisms." 10/01/2004 - "Oral immunization with a combination of Plasmodium yoelii merozoite surface proteins 1 and 4/5 enhances protection against lethal malaria challenge." 10/01/2012 - "These issues are particularly relevant to malaria vaccine candidate studies that are directed against surface proteins that the parasites use to gain entry into erythrocytes. " 06/01/2009 - "This finding allowed us to extend some conclusions of our studies to a larger group of the malaria surface proteins. " Order ALL the reference details at left...
4.	Pneumonia (Pneumonitis) 08/01/1997 - "The ability to induce protection against a genital challenge was studied in BALB/c female mice with three Chlamydia trachomatis mouse pneumonitis (MoPn) major outer membrane protein (MOMP) preparations as well as an acellular vaccine consisting of the chlamydial outer membrane complex (COMC). " 09/01/2009 - "Biophysical and stabilization studies of the Chlamydia trachomatis mouse pneumonitis major outer membrane protein." 10/01/2001 - "trachomatis mouse pneumonitis (MoPn) major outer membrane protein (MOMP). " 10/01/2001 - "Immunization with the Chlamydia trachomatis mouse pneumonitis major outer membrane protein can elicit a protective immune response against a genital challenge." 10/01/1996 - "To quantify the serum antibody responses to Pasteurella multocida A:3 outer membrane proteins (OMP) for cattle vaccinated with the homologous serogroup and to correlate those responses with the extent of experimentally induced pneumonia. " Order ALL the reference details at left...
5.	Human Influenza (Influenza) 11/02/2012 - "Because influenza is an enveloped virus, the entry, assembly, and budding of virus particles are essential steps in the viral life cycle, and the virus relies on the participation of host cellular membrane proteins for all of these steps. " 02/01/2011 - "The surface proteins of human influenza A viruses experience positive selection to escape both human immunity and, more recently, antiviral drug treatments. " 02/01/2011 - "Prevalence of epistasis in the evolution of influenza A surface proteins." 10/01/2009 - "Phylogenetic analysis of the surface proteins of influenza A (H5N1) viruses isolated in Asian and African populations." 10/01/2009 - "Between such rare events, the evolution of influenza is shaped by antigenic drift: the accumulation of mutations that result in changes in exposed regions of the viral surface proteins. " Order ALL the reference details at left...

Related Drugs and Biologics

1.	Antigens
2.	Antibodies
3.	Proteins (Proteins, Gene)
4.	Membrane Proteins (Integral Membrane Proteins)
5.	Immunoglobulin G (IgG)
6.	Monoclonal Antibodies
7.	Vaccines
8.	Epitopes
9.	Immunoglobulin A (IgA)
10.	Hemagglutinins (Hemagglutinin)

Related Therapies and Procedures

1.	Transplants (Transplant)
2.	Heterologous Transplantation (Xenotransplantation)
3.	Ligation
4.	Peritoneal Dialysis
5.	Microspheres (Microsphere)

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