Sugars

Short chain carbohydrate molecules that have hydroxyl groups attached to each carbon atom unit with the exception of one carbon that has a doubly-bond aldehyde or ketone oxygen. Cyclical sugar molecules are formed when the aldehyde or ketone groups respectively form a hemiacetal or hemiketal bond with one of the hydroxyl carbons. The three dimensional structure of the sugar molecule occurs in a vast array of biological and synthetic classes of specialized compounds including AMINO SUGARS; CARBASUGARS; DEOXY SUGARS; SUGAR ACIDS; SUGAR ALCOHOLS; and SUGAR PHOSPHATES.

Also Known As:

Networked: 11126 relevant articles (291 outcomes, 1109 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Johnson, Richard J: 30 articles (05/2021 - 10/2007)
2.	Lanaspa, Miguel A: 24 articles (05/2021 - 09/2011)
3.	Tokuda, Masaaki: 22 articles (01/2021 - 01/2004)
4.	Avena, Nicole M: 16 articles (12/2015 - 06/2002)
5.	Welsh, Jean A: 15 articles (12/2021 - 01/2011)
6.	Stanhope, Kimber L: 15 articles (02/2021 - 03/2010)
7.	Sievenpiper, John L: 14 articles (01/2022 - 08/2013)
8.	Goran, Michael I: 14 articles (01/2022 - 11/2005)
9.	Hu, Frank B: 14 articles (12/2021 - 08/2004)
10.	Beier, John C: 14 articles (04/2021 - 09/2003)

Related Diseases

1.	Obesity 01/01/2022 - "Tokelauans reduced fat, dramatically reduced SFA, and increased sugar intake: obesity and diabetes rose. " 04/03/2022 - "In conclusion, children with obesity who were able to decrease their BMI implemented a significant reduction in consumption of foods with high sugar content. " 02/26/2020 - "In a large mother-child cohort, a dietary pattern characterised by high sugar and fat foods was associated with greater adiposity and obesity risk in children aged 6 years, while a 'Healthy' dietary pattern offered some protection against obesity. " 01/01/2020 - "Given the significant healthcare cost of obesity to society, this improved understanding could help public health initiatives focusing on manufacturing food that is lower in sugar." 05/18/2015 - "With high prevalence rates of obesity and other diet-related diseases, improved methods for monitoring sugar levels in breakfast cereals would be useful in nutrition research. "
2.	Neoplasms (Cancer) 01/01/2017 - "While each individual imaging and treatment step requires a long time period in effective treatment of diseases, these multifunctional sugar based nanoparticles will have the advantage of rapid detection, right drug efficiency evaluation and immediate interfere opportunity to some important diseases, especially rapidly progressing cancers. " 09/21/2022 - "These sugar-coated bullets selectively target tumor cells through passive and active targeting, resulting in high in vivo therapeutic efficacy in an orthotopic HCC mouse model. " 11/01/2013 - "Replacement of the THF segment with a sugar residue may deliver analogues with improved tumor selectivity and pharmacokinetics and are therefore attractive for drug development. " 12/08/2022 - "Human epidemiologic studies and mechanistic preclinical studies in multiple cancers support a causal link between excess sugar and cancer. " 11/11/2020 - "The objective was to study the associations between total and added sugar intake and cancer risk (overall, breast, and prostate), taking into account sugar types and sources. "
3.	Body Weight (Weight, Body) 01/01/2015 - "In 21-day study, treated diabetic rats showed significant improvement in terms of fasting BG, body weight, and urine sugar as compared to control diabetic rats. " 05/04/2018 - "Garcinia gummi-gutta (GGG) rind extract is effective for reducing appetite, body weight and adiposity of obese rodents fed high-fat (HF), high-sugar (HS) or high fat/sugar (HFS)-based diets, but these effects have not been simultaneously evaluated. " 01/01/2022 - "The present study provides a comprehensive time-trends analysis of added sugars intakes and contributing sources in the diets of US children, adolescents, and teens (2-18 years) from 2001-2018, focusing on variations according to sociodemographic factors (age, sex, race and ethnicity, income), food assistance, and health-related factors (physical activity level, body weight status). " 07/01/2021 - "Our study objectives were to examine intakes of total, free and added sugar among preschool-aged children and to investigate their associations with body weight, body mass index Z-scores, percent fat mass and waist circumference. " 01/01/2021 - "Changes in Added Sugar Intake and Body Weight in a Cohort of Older Australians: A Secondary Analysis of the Blue Mountains Eye Study."
4.	Type 2 Diabetes Mellitus (MODY) 02/01/2023 - "Effectiveness of the SUGAR intervention on hypoglycaemia in elderly patients with type 2 diabetes: A pragmatic randomised controlled trial." 01/01/2022 - "The Richmond Stress and Sugar Study includes a racially and socioeconomically diverse cohort of adults at risk for type 2 diabetes ( n = 125; mean age = 57 years, 48% Black, and 61% high neighborhood socioeconomic status [SES]). " 10/01/2021 - ""A Touch of Sugar": A Qualitative Study of the Impact of Health Beliefs on Type 1 and Type 2 Diabetes Self-Management Among Black Canadian Adults." 01/01/2021 - "Randomised controlled trial of pharmacist-led patient counselling in controlling hypoglycaemic attacks in older adults with type 2 diabetes mellitus (ROSE-ADAM): A study protocol of the SUGAR intervention." 01/01/2020 - "The Richmond Stress and Sugar Study recruited 125 adults at elevated risk of type 2 diabetes using a two-by-two sampling frame wherein non-Hispanic whites and African Americans (AAs) were each recruited from neighborhoods of higher and lower socioeconomic status (SES). "
5.	Infections 01/01/1991 - "Granulated sugar treatment is effective in refractory, severe mediastinal infections." 06/01/2009 - "The discovery of several transmembrane receptors expressed by antigen presenting cells, including those that detect and interact with specific sugar moieties on the surface of microbes, has improved our understanding of how immunity against infection is generated. " 07/01/1996 - "Improved diagnosis of low intensity Spirocerca lupi infection by the sugar flotation method." 03/20/2023 - "Although a high-fat diet has been extensively studied for its involvement in various diseases, fewer studies have examined the impact of a high-sugar diet on the development of certain diseases, particularly enteric infections. " 11/27/2022 - "In the current study, we aimed to evaluate the susceptibility of 25 sugar beet cultivars to infection with powdery mildew disease under Egyptian conditions. "

Related Drugs and Biologics

1.	Glucose (Dextrose)
2.	Proteins (Proteins, Gene)
3.	Sugars
4.	Insulin (Novolin)
5.	Salts
6.	Starch (Cornstarch)
7.	Fats
8.	Hypoglycemic Agents (Hypoglycemics)
9.	Solutions
10.	psicose (D-psicose)

Related Therapies and Procedures

1.	Therapeutics
2.	Canes (Cane)
3.	Glycemic Control
4.	Toothbrushing
5.	Fluid Therapy (Oral Rehydration Therapy)