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Body Weight (Weight, Body)

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The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.

Also Known As:

Weight, Body; Body Weights; Weights, Body

Networked: 70281 relevant articles (2867 outcomes, 5372 trials/studies) for this Disease, Comments

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Disease Context: Research Results

Related Diseases

1.	Infection
2.	Neoplasms (Cancer)
3.	Weight Loss (Weight Reduction)
4.	Obesity
5.	Insulin Resistance

Experts

1.	National Toxicology Program: 31 articles (09/2012 - 01/2001)
2.	Yokozawa, Takako: 28 articles (11/2011 - 09/2002)
3.	Woods, Stephen C: 24 articles (01/2013 - 02/2002)
4.	Seeley, Randy J: 24 articles (01/2013 - 06/2002)
5.	Pari, Leelavinothan: 24 articles (09/2012 - 01/2002)
6.	Kangawa, Kenji: 21 articles (10/2012 - 04/2003)
7.	Sultana, Sarwat: 20 articles (06/2012 - 03/2003)
8.	Tschöp, Matthias H: 19 articles (01/2013 - 08/2003)
9.	Sil, Parames C: 19 articles (06/2012 - 09/2005)
10.	Astrup, Arne: 18 articles (01/2012 - 01/2002)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Body Weight:

1.	Insulin (Novolin)FDA Link 01/01/2007 - "CFRD is related to decreased life expectancy, most notably in female patients, as well as to decreased pulmonary function and body weight reduction, which can be improved with adequate insulin therapy. " 01/01/2010 - "Treatment with TFLC showed a significant increase in insulin sensitivity, serum HDL-C level and SOD activities, meanwhile marked decrease in body weight, serum FFA, TC, TG, LDL-C, CRP, MDA content. " 12/05/2012 - "Furthermore, Tyk2(-/-) mice expressing CAStat3 transgene in BAT also show improved BAT development, normal levels of insulin, and significantly lower body weights. " 01/01/2012 - "Switching to chow food from high fat diet reduced the body weight and improved insulin sensitivity but not affecting the expressions of studied inflammatory genes in DIO rats. " 04/01/2010 - "Exercise resulted in a significant reduction in body weight and fasting insulin and an increase in AG plasma levels and fasting hunger sensations. " Order ALL the reference details at left...
2.	Glucose (Dextrose)FDA LinkGeneric 06/01/2010 - "In conclusion, a 16-week exercise training program improved cardiac autonomic modulation in response to an oral glucose load in obese adults, independently of diabetes status, and in the absence of remarkable changes in body weight, body composition, fitness level, and glycemic control." 11/14/2012 - "As a consequence, mice lacking AgRP-neurons become obese and hyperinsulinemic on regular chow but display reduced body weight gain and paradoxical improvement in glucose tolerance on high-fat diet. " 11/05/2012 - "BER reduced body weight and caused a significant improvement in glucose tolerance without altering food intake in diabetic rats. " 05/01/2011 - "Body weight and waist circumference were significantly reduced, and liver function, lipid profiles and glucose metabolism were significantly improved in both groups. " 04/01/2011 - "The intervention group significantly improved their diabetes knowledge, motivation to change, positive affect, healthy eating and activity levels and showed significantly greater reductions in weight, body mass index, waist circumference, diastolic blood pressure and fasting plasma glucose in comparison with controls. " Order ALL the reference details at left...
3.	Blood Glucose (Blood Sugar)IBA 10/01/1995 - "Nineteen of these products were effective, when administered at an oral dose of 100 mg/kg body weight in inducing a marked reduction in blood glucose level." 05/01/2012 - "This study has shown that a 10-week intervention to promote physical activity was effective in significantly decreasing the population's BP by 1.56 / 0.74 mm Hg, fasting blood sugar levels by 2.82 mg%, body weight by 0.17 kg, and BMI by 0.06 kg / m(2). " 07/22/1994 - "In this study feeding diabetic rats and rabbits with 0.39 g/kg body weight of the aqueous extract of the aerial parts of the plant for 2-4 weeks shows a significant reduction in blood glucose level, prevents elevation of glycosylated haemoglobin level and possesses a hypoliposis effect, in addition to the protection against body weight loss of diabetic animals." 03/01/2010 - "It was shown that treatment with the high-fiber diet (46-55 g/day) in combination with mineral water markedly accelerated normalization of blood glucose level and lipid metabolism, reduction of body weight and arterial pressure; moreover, it improved general efficiency of therapy." 05/01/2009 - "There was significant improvement in both fasting and post-prandial blood glucose levels, body weight, HbA1C, and lean mass. " Order ALL the reference details at left...
4.	CholesterolIBA 12/19/2003 - "In mature mice between 13 and 26 weeks of age, there was a marked decrease in these parameters including a reduction in the relative size of the CNS to 1.7% of body weight, a decrease in the rate of sterol accretion to 0.012 mg/day, and a reduction in the rate of cholesterol synthesis to 0.035 mg/day. " 02/01/2003 - "Finally, statin therapy and better compliance to dietary recommendations resulted in the normalisation of cholesterol level, a marked decrease in triglyceride concentration and a loss of 5 kg of body weight. " 01/01/2001 - "After the six months of the program: 1) Total cholesterol levels had decreased significantly, along with both systolic and diastolic blood pressure, body weight and BMI; 2) Major nutrient intake, density of nutrients and eating behavior were improved, with decrease in daily salt intake, and increase significant in daily energy expenditure; 3) Stress scores by the Nichidai stress check were decreased significantly, subjects with higher stress scores at the beginning of programs having marked change, and neurotic tendencies were decreased in CMI categories II-IV. These results suggest that, in order to maintain and/or improve the QOL of climacteric women, good dietary habits and physical activities, such as walking, and psychological support are essential. " 01/01/2009 - "Black participants with A1(+) genotypes had significantly greater mean body weight (11.2 kg heavier, P = 0.05) and greater intake of fat (P = 0.002), saturated fat (P = 0.01), and cholesterol (P = 0.02) compared with A2A2 (A1(-)) individuals; dietary changes during the study did not favor one genotype group. " 03/01/2010 - "KBG led to a significant reduction in liver injury tests and blood cholesterol but had no effects on body weight in all NAFLD cases. " Order ALL the reference details at left...
5.	CreatinineIBA 11/01/2011 - "The most popular recommended formulas are the simple Cockcroft-Gault equation, which is inaccurate and biased, as it calculates clearance of creatinine in proportion to body weight, and the MDRD equation, which is more accurate, but systematically underestimates normal and high GFR, being established by a statistical analysis of results from renal-insufficient patients. " 05/01/1987 - "Measured CLcr values ranged from 29.8 to 197 mL/min in group 1 and from 2.8 to 118 mL/min in group 2. Ranges of SCr values were 0.7-1.5 mg/dL (mean, 1.1) in group 1 and 1.6-7.1 mg/dL (mean, 2.8) in group 2; the formula of Cockcroft and Gault, which uses age, body weight, and SCr, had the highest correlation and the greatest accuracy in group 1, whereas the formula of Jelliffe, which uses body surface area and SCr, had the highest correlation and the greatest accuracy in group 2. Estimation of creatinine clearance can be improved by identification and use of the formula that is best suited to a specific patient population." 03/31/1998 - "The loss of body weight was accompanied by a marked decrease in plasma creatinine. " 07/01/2004 - "The suppression of body weight gain and reduction of creatinine clearance were significantly greater with the 20:00h than 08:00h treatment. " 06/01/2004 - "Patients with creatinine less than 1 mg/dl had significantly greater increase in body weight (at 3 and 6 months) as well as crown-heel length (at 3 and 9 months), respectively (p <0.05). " Order ALL the reference details at left...
6.	LeptinIBA 06/01/2005 - "Recent studies indicate that the passive range of motion exercise of the extremities results in a significantly greater increase of body weight, increased bone mineralization, increased bone formation markers and leptin levels, and attenuation of the natural post-natal decline in bone SOS. " 05/01/2002 - "In the present study, we tested the hypothesis that a single daily injection of the gut peptide CCK, together with continuous leptin infusion, would produce significantly greater loss of body weight than leptin alone. " 10/01/2011 - "The rats treated with LV-SOCS3-shRNA exhibited enhanced leptin-induced Stat3 activation, decreased body weight gain and improved metabolic parameters when exposed to a high-fat diet. " 07/01/2010 - "The bio-functional experiments of purified Leptin showed a significant reduction in food intake and body weight of female mice treated with Leptin by comparing with control mice, and it indicated that the purified Leptin has full biological activity. " 01/01/2010 - "Increased leptin expression in the CRT group did not result in increased circulating leptin or a statistically significant reduction in body weight during the treatment period. " Order ALL the reference details at left...
7.	Triglycerides (Triacylglycerol)IBA 10/01/2003 - "After adjusting for age and smoking, we found that body weight, body mass index, waist and hip circumferences, fat mass, fat-free mass, intra-abdominal fat and triglycerides were significantly greater in women with the A allele compared with the G allele ( p=0.001-0.025). " 01/01/2011 - "Whereas, maternal HF diet reduces body weight gain and circulating triglycerides, and ameliorates corpulence index of offspring, even when subjected to P diet. " 03/21/2005 - "After 41 days of DCM extract administration at a dose of 300 mg/kg/day, diabetic rats showed improvement in glycemia, body weight, triglycerides, and GPT in comparison with the diabetic control group. " 01/01/2011 - "This study presents striking differences in postprandial triglycerides patterns between rats and mice not correlated to baseline triglycerides, the animal baseline body weight or fat load in all animal groups." 11/01/2010 - "The current study examined both short- and long-term effects of HFCS on body weight, body fat, and circulating triglycerides. " Order ALL the reference details at left...
8.	Urea (Carbamide)FDA LinkGeneric 04/11/2007 - "Both doses of DHB ameliorated the rise in serum urea and Cr concentrations and improved the changes in kidney and body weights significantly. " 12/01/1999 - "After 65 days the average body weight of the pigs injected with pSP-HV-GHRH was approximately 37% greater than the placebo-injected controls and resulted in a significant reduction in serum urea concentration, indicating a decrease in amino acid catabolism. " 07/01/2000 - "Replacing alfalfa with red clover improved body weight gain and reduced concentrations of milk and blood urea and ruminal NH3. " 04/01/2009 - "The study was conducted at Sinana Agricultural Research Center, Ethiopia to assess the supplementation of graded levels of vetch (Vicia dasycarpa 'lana') and lucerne (Medicago sativa,' Hunter river') hay on feed intake, digestibility and body weight (BW) change of Arsi-Bale sheep fed urea treated barley straw (UTBS). " 09/01/2008 - "The median (and mode) blood flow was 200mL/min. Given the information supplied on pre-dilution rates, the median blood flow, and estimates of haematocrit and body weight based on previous surveys, the "typical" prescribed CRRT urea clearance dose ("standard") before the RENAL trial was estimated to be approximately 25 mL/kg/h. " Order ALL the reference details at left...
9.	NitrogenIBA 03/01/1993 - "Feeding of diet containing insect infested sorghum grains (50 and 75%) resulted in marked decrease in food intake, protein intake, gain in body weight, food efficiency ratio, protein efficiency ratio, nitrogen consumption, nitrogen absorption, biological value, net protein utilization, dry matter digestibility, net protein retention and protein retention efficiency. " 07/01/1988 - "Treatment of rats with recombinant human TNF initially causes a marked decrease in food intake, a loss of body weight, and a negative nitrogen balance. " 02/01/2009 - "The data for dry weight, body mass index, and normalized protein nitrogen appearance, which represent nutritional status, showed a significant improvement while still maintaining a satisfactory albumin level. " 12/01/1983 - "This method of nutritional intake allowed us to: maintain body weight at pre-operative values; obtain a positive nitrogen balance on average the sixth postoperative day; reduce the volume of parenteral support, early suspension and a significant reduction in complications connected with this method." 11/01/1984 - "Nutritional status was improved (e.g., positive nitrogen balance was established); the patient absorbed nutrients better; and some lean body mass was restored, while total body weight decreased." Order ALL the reference details at left...
10.	Insulin-Like Growth Factor I (IGF-1)IBA 12/01/2007 - "Disruption of local IGF-I dramatically reduced body weight 28-37%, femur areal bone mineral density 10-25%, and femur bone size 18-24% in growing mice. " 07/01/2008 - "The current treatment using an initial low dose of hrGH followed by individualised dose titration adjusted according to serum IGF-1 levels, leads to similar beneficial effects with less incidence of side effects, improved tolerance to treatment and a lower stable GH dose as compared to hrGH replacement therapy based on body weight or body surface area. " 11/01/2003 - "As compared with healthy rats, administration of 20 microg human recombinant IGF-I/kg body weight for 14 d to cirrhotic rats significantly improved N balance variables and restored in vivo intestinal transport of the sugar. " 02/01/2003 - "In IGF-I-treated rats, serum concentration of IGF-I and final body weight were significantly greater because of a proportionate increase in carcass lean body mass than in vehicle-treated rats. " 01/01/1995 - "The reduction of GH secretion was associated with a decreased body weight and a significant reduction in plasma IGF-I concentration. " Order ALL the reference details at left...

Therapies and Procedures

1.	Oral Administration 06/01/2012 - "Oral administration of ALA in diabetic mice fed on a high-fat diet and db/db mice dramatically reduced the body weight and visceral fat content. " 08/01/2005 - "The oral administration of TPI markedly improved the FTD-induced toxicity, as evaluated by the decrease in the body weight of the mice. " 07/01/2012 - "Oral administration of Chana 1 at a dose of 50 mg/kg body weight/day significantly improved Aβ-induced learning and memory impairment in mice, as measured in Y-maze and passive avoidance tests. " 10/07/2008 - "Chronic oral administration of HDACi 4b, beginning after the onset of motor deficits, significantly improved motor performance, overall appearance, and body weight of symptomatic R6/2(300Q) transgenic mice. " 01/01/2008 - "Oral administration of "TpASet" at a dose of 600 mg/kg body weight showed significant improvement in above mentioned parameters. " Order ALL the reference details at left...
2.	Injections 12/01/2011 - "Intraperitoneal (i.p.) injections with anti-LIF antibody (7.5 µg/g body weight, 3 times) between D3 (D1 = day of vaginal plug detection) and D4 effectively blocked embryo implantation; complete inhibition was achieved in C57BL/6J mice, and implantation was dramatically reduced in ICR mice (reduced to 27%). " 11/15/2002 - "We did not find any effect of PrRP-31 on food intake after single injections of up to an 8-nmol dose, but observed a marked decrease in food intake and body weight in rats that received a repeated twice daily administration of 8 nmol of PrRP-31. " 11/01/1984 - "Through repeated NE injections, the present study set out to determine whether chronic noradrenergic stimulation of the PVN is effective in producing changes in total daily food intake, as well as in body weight gain. " 05/01/2005 - "Four weekly injections with 20 mg/kg body weight not only reduced storage in peripheral tissues progressively, but also were surprisingly effective in reducing sulfatide storage in brain and spinal cord. " 11/15/2010 - "Product information and pivotal studies on newly marketed injectable medications were reviewed to determine whether a weight descriptor was included and if information was provided for dosing patients with extremes of body weight. " Order ALL the reference details at left...
3.	Aftercare (After-Treatment) 11/01/2011 - "There was a significant reduction in body weight, organs and increased body temperature, locomotor activity after treatment with extracts. " 01/01/2007 - "UC activity index was lower and body weight was higher in the two CE groups than those in the model group respectively, showing significant difference (P < 0.05 or P < 0.01); pathological examination showed the pathological changes and inflammatory response in colonic tissue were relieved significantly after treatment, and the improvement in the CE-H group was better than that in the SASP group. " 01/01/2005 - "A significant reduction in the body weight after treatment reflected by a significant reduction in the BMI was noted. " 02/01/2001 - "3. Body weight decrease was significantly greater in LPS-treated rats compared with control rats 3, 5 and 8 hr after treatment. " 12/01/1992 - "In mice treated with 200 mg of CLARI per kg of body weight six times weekly, however, CLARI-resistant organisms were isolated from the spleens of all mice examined after treatment for 8 weeks; the mean CFU per spleen and the frequency of resistant mutants were significantly greater than those of control mice and increased further after treatment for 16 weeks. " Order ALL the reference details at left...
4.	Subcutaneous Injections 12/01/2012 - "For this study, 2-month-old male ICR-CD1 mice were treated by a single subcutaneous injection of 1, 2 and 3 mg CdCl(2)/kg body weight and killed after 35 days. " 06/01/2004 - "In our studies, AOM was administered to adult BDIX/OrlIco rats by four weekly subcutaneous injections of 15 mg/kg body weight each - two periods of 2 weeks of AOM treatment separated by a one-week break. " 08/01/1997 - "To examine this possibility, the present study compared treatment-induced brain expression of the immediate-early gene product c-Fos as a marker of neural activation in adult and two-day-old rats after subcutaneous injection of 2 M NaCl (0.1 ml/10 g body weight). " 10/01/1978 - "Volume-pressure diagrams during inflation with air and saline were made with the lungs of 6 control dogs and 24 dogs with acute alveolar injury induced by subcutaneous injection of 6 mg of N-nitroso-N-methylurethane per kg of body weight 3 to 14 days before study. " 12/01/2012 - "At 7 and 8 weeks of age, rats received two successive subcutaneous injections of AOM at 20 mg/kg body weight. " Order ALL the reference details at left...
5.	Drug Therapy (Chemotherapy) 05/01/2011 - "The patient gained 10 kg in body weight even after 12 months of aggressive chemotherapy, and has attained a longstanding partial remission from the disease. " 06/01/2006 - "SI could not raise the efficacy of chemotherapy on NSCLC, but improve the quality of life, raise the body weight of patients and alleviate adverse reaction of chemotherapy as myelosuppression so as to improve the tolerance of organism to chemotherapy." 02/01/2001 - "In a secondary analysis of participants stratified by type of adjuvant therapy, supervised exercise improved aerobic capacity (+3.5 mL/kg/min; P =.01) and reduced body weight (-4.8 kg; P <.05) compared with usual care only in participants not receiving chemotherapy. " 05/01/2012 - "Practice pattern studies demonstrate that up to 40% of obese patients receive limited chemotherapy doses that are not based on actual body weight. " 04/01/2010 - "Clinical studies have documented that cytotoxic chemotherapy is often associated with body weight loss and decreased enjoyment of food. " Order ALL the reference details at left...

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