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Member 2 Subfamily B ATP Binding Cassette Transporter

An ATP-binding cassette, sub-family B protein (ATP BINDING CASSETTE TRANSPORTER, SUBFAMILY B) that functions in the transport of ANTIGENS from the CYTOPLASM to the ENDOPLASMIC RETICULUM for association with HISTOCOMPATIBILITY ANTIGENS CLASS I peptides. It also acts as a molecular scaffold for the final stage of MHC class I PROTEIN FOLDING.
Also Known As:
ATP Binding Cassette Transporter, Subfamily B, Member 2; ABCB2 Protein; ATP Binding Cassette Transporter, Sub-Family B, Member 2; ATP-Binding Cassette Sub-Family B Member 2; Antigen Peptide Transporter-1; Peptide Transporter PSF1; Peptide Transporter TAP1; RING4 Protein; Really Interesting New Gene 4 Protein; TAP-1 Protein; TAP1 Protein; Transporter 1, ATP-Binding Cassette, Sub-Family B (MDR-TAP); ATP Binding Cassette Sub Family B Member 2; Antigen Peptide Transporter 1; PSF1, Peptide Transporter; TAP 1 Protein; TAP1, Peptide Transporter
Networked: 9 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1. Dummer, Reinhard: 2 articles (08/2020 - 01/2020)
2. Friedrich, Michael: 2 articles (08/2020 - 01/2020)
3. Handke, Diana: 2 articles (08/2020 - 01/2020)
4. Koelblinger, Peter: 2 articles (08/2020 - 01/2020)
5. Lazaridou, Maria-Filothei: 2 articles (08/2020 - 01/2020)
6. Massa, Chiara: 2 articles (08/2020 - 01/2020)
7. Mueller, Anja: 2 articles (08/2020 - 01/2020)
8. Seliger, Barbara: 2 articles (08/2020 - 01/2020)
9. Feng, Yu: 1 article (06/2022)
10. Fu, Yan: 1 article (06/2022)

Related Diseases

1. Melanoma (Melanoma, Malignant)
2. Colorectal Neoplasms (Colorectal Cancer)
3. Pancreatic Neoplasms (Pancreatic Cancer)
4. Neoplasms (Cancer)
5. Hepatocellular Carcinoma (Hepatoma)

Related Drugs and Biologics

1. Histocompatibility Antigens Class I
2. Mitogen-Activated Protein Kinase Kinases (MEKs)
3. Cytokines
4. Messenger RNA (mRNA)
5. RNA (Ribonucleic Acid)
6. Proteins (Proteins, Gene)
7. beta 2-Microglobulin (beta 2 Microglobulin)
8. Surface Antigens (Surface Antigen)
9. Antibodies