18 16 11 Types 6 Human Papillomavirus Recombinant Vaccine Quadrivalent (Gardasil)

A vaccine containing L1 capsid proteins from four types of HPV (ALPHAPAPILLOMAVIRUS), types 6, 11, 16 and 18 that is used to prevent infections from human papillomaviruses of these subtypes.

Also Known As:

Gardasil; Human Papillomavirus Recombinant Vaccine Quadrivalent, Types 6, 11, 16, 18; HPV L1 Vaccine, Quadrivalent 6,11,16,18; Human Papillomavirus Vaccine L1, Type 6,11,16,18; Human Papillomavirus Vaccine L1, Types 6,11,16,18

Networked: 158 relevant articles (25 outcomes, 16 trials/studies)

Relationship Network

Drug Context: Research Results

Complex Mixtures: 1906
- Biological Products
  - Vaccines: 124365
    - Combined Vaccines: 2170
      - 18 16 11 Types 6 Human Papillomavirus Recombinant Vaccine Quadrivalent: 158
    - Viral Vaccines: 462
      - Papillomavirus Vaccines: 3037
        18 16 11 Types 6 Human Papillomavirus Recombinant Vaccine Quadrivalent: 158

Experts

1.	Harper, Diane M: 6 articles (01/2017 - 01/2009)
2.	Haupt, Richard M: 5 articles (09/2015 - 04/2010)
3.	Roden, Richard B S: 3 articles (01/2018 - 02/2013)
4.	Bonanni, Paolo: 3 articles (01/2017 - 07/2010)
5.	Shoenfeld, Yehuda: 3 articles (01/2017 - 01/2014)
6.	Tomljenovic, Lucija: 3 articles (01/2017 - 01/2014)
7.	Block, Stan L: 3 articles (09/2015 - 06/2010)
8.	Schiller, John T: 3 articles (06/2014 - 08/2008)
9.	Sehnal, Borek: 2 articles (01/2022 - 01/2016)
10.	Sláma, Jiří: 2 articles (01/2022 - 01/2016)

Related Diseases

1.	Condylomata Acuminata (Genital Wart) 08/19/2008 - "Gardasil was also highly efficacious at preventing vaginal/vulvar lesions and genital warts. " 02/01/2008 - "Data from the Phase III trial demonstrated that Gardasil was 100% effi cacious in preventing precancerous lesions of the cervix, vulva, and vagina and effective against genital warts. " 11/23/2010 - "Gardasil offers protection against CIN 2+ lesions caused by HPV 16/18 and against genital warts caused by HPV 6/11 for at least 5 years. " 07/05/2010 - "GARDASIL has been shown to reduce the incidence of pre-cancerous cervical, vulvar, and vaginal lesions, and external genital warts causally related to HPV6/11/16/18. " 11/01/2009 - "Gardasil approved to prevent genital warts in men and boys."
2.	Papillomavirus Infections 01/01/2020 - "We used a questionnaire including 5 sections as follows; Patients demographic information, Patients medical history, Pregnancy and lactation considerations, Gardasil prescription characteristics and HPV infection characteristics. " 03/01/2010 - "Gardasil has been shown to be safe and effective in preventing HPV infections by types 6, 11, 16, and 18; types 16 and 18 are associated with 2 high-risk types of cervical cancer and are associated with 70% of all cervical cancers. " 07/01/2006 - "Cervarix and Gardasil are effective for prevention of HPV infection and cervical lesions. " 10/13/2015 - "The quadrivalent (types 6/11/16/18) human papillomavirus (HPV) vaccine, Gardasil, has demonstrated efficacy against persistent HPV infection and associated anogenital disease in males. " 06/01/2010 - "Two prophylactic vaccines are currently available for the prevention of genital HPV infection: a quadrivalent (Gardasil); Merck & Co. "
3.	Uterine Cervical Neoplasms (Cancer of the Cervix) 10/01/2013 - "The study subjects were interviewed in either Hindi or English; subsequently the awareness of HPV-mediated cervical cancer and knowledge of Gardasil vaccination was assessed in terms of "yes", "no" and "no response". " 10/01/2013 - "The present study, therefore, aimed to evaluate cervical cancer awareness and knowledge of Gardasil vaccination in North Indian women. " 01/01/2019 - "Following a human papillomavirus (HPV) vaccination initiative (Gardasil) in Eldoret, Kenya, the knowledge and source of information of cervical cancer and acceptance of prevention strategies among vaccinated and unvaccinated adolescents were evaluated. " 10/01/2013 - "Our pilot survey may help in assessing knowledge of HPV-mediated cervical cancer and Gardasil vaccination awareness in women, and accordingly develop cost-effective cervical cancer control and prevention/public health counseling sessions in a clinical setting. " 10/01/2013 - "Human Papillomavirus-mediated cervical cancer awareness and Gardasil vaccination: a pilot survey among North Indian women."
4.	Neoplasms (Cancer) 08/01/2010 - "The background material is based on data from a screening programme with centralized records dating back to 1964, as well as from population-based studies on the distribution of oncogenic HPV types in cancer and histologically verified CIN2-3 lesions and from the Icelandic arm of the Future II trial with Gardasil. " 01/01/2014 - "For the association between Gardasil and HPV-associated vulval/vaginal intraepithelial neoplasia grades 2-3, the overall OR and 95% CI was 2.25 (95% CI: 0·78, 6.50). " 10/01/2006 - "The clearly defined causation by papillomavirus (HPV) and precursor lesions of cervical cancer have made this cancer largely preventable through Pap screening programs, and now by vaccination with Gardasil. " 11/04/2022 - "To combat increasing HPV-related cancers, the 9-valent HPV vaccine Gardasil was developed. " 01/01/2021 - "To conclude, Gardasil HPV types have decreased, but it is still important to follow remaining HR-HPV types and cancer development, since there is an ongoing increase in the incidence of HPV-associated tonsillar and base of tongue cancer, and cervical cancer in Sweden."
5.	Infections 01/01/2017 - "The past ten years of Gardasil use has provided evidence of reduced HPV 16/18 infections in countries where there has been high coverage. " 01/01/2019 - "In our patient, the Gardasil vaccine did not provide crossover protection against HPV 45 infection. " 01/01/2016 - "Characterization of serum antibodies from women immunized with Gardasil: A study of HPV-18 infection of primary human keratinocytes." 01/01/2014 - "Despite the fact that both men and women carry the human papillomavirus (HPV) and jointly contribute to its status as an epidemic, the promotion of Gardasil, a vaccine that blocks infection from four strains of HPV, has largely been designated as a women's-only health issue. " 01/01/2010 - "Incident HPV 51 Infection After Prophylactic Quadrivalent Human Papillomavirus (Types 6, 11, 16, and 18) L1 Virus-Like Particle Vaccine Gardasil/Silgard."

Related Drugs and Biologics

1.	Vaccines
2.	18 L1 type 16 human papillomavirus vaccine (Cervarix)
3.	Papillomavirus Vaccines (HPV Vaccines)
4.	Neutralizing Antibodies
5.	Therapeutic Uses
6.	Influenza Vaccines (Influenza Vaccine)
7.	Combined Vaccines
8.	Proteins (Proteins, Gene)
9.	Meningococcal Vaccines (Meningococcal Vaccine)
10.	Antibodies

Related Therapies and Procedures

1.	Immunotherapy
2.	Postcoital Contraception (Emergency Contraception)
3.	Therapeutics
4.	Combined Modality Therapy