HLA-DRB1*04:02 antigen

Also Known As:

HLA Dw10; HLA-DRB1*0402; HLA-DRB1*04:02; HLA-Dw10; HLA-Dw10 antigen

Networked: 12 relevant articles (1 outcomes, 1 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Carbohydrates: 22023
- Glycoconjugates: 1353
  - Glycoproteins: 24834
    - Membrane Glycoproteins: 2252
      - Histocompatibility Antigens Class II: 2170
        HLA-D Antigens: 238
        HLA-DR Antigens: 5477
        HLA-DR beta-Chains: 64
        HLA-DRB1 Chains: 2199
        HLA-DRB1*04:02 antigen: 12
Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Glycoproteins: 24834
    - Membrane Glycoproteins: 2252
      - Histocompatibility Antigens Class II: 2170
        HLA-D Antigens: 238
        HLA-DR Antigens: 5477
        HLA-DR beta-Chains: 64
        HLA-DRB1 Chains: 2199
        HLA-DRB1*04:02 antigen: 12
  - Membrane Proteins: 10078
    - Membrane Glycoproteins: 2252
      - Histocompatibility Antigens Class II: 2170
        HLA-D Antigens: 238
        HLA-DR Antigens: 5477
        HLA-DR beta-Chains: 64
        HLA-DRB1 Chains: 2199
        HLA-DRB1*04:02 antigen: 12
Biological Factors: 2472
- Antigens: 143924
  - Surface Antigens: 5813
    - Histocompatibility Antigens: 1132
      - HLA Antigens: 8934
        HLA-D Antigens: 238
        HLA-DR Antigens: 5477
        HLA-DR beta-Chains: 64
        HLA-DRB1 Chains: 2199
        HLA-DRB1*04:02 antigen: 12
      - Histocompatibility Antigens Class II: 2170
        HLA-D Antigens: 238
        HLA-DR Antigens: 5477
        HLA-DR beta-Chains: 64
        HLA-DRB1 Chains: 2199
        HLA-DRB1*04:02 antigen: 12
  - Isoantigens: 1221
    - Histocompatibility Antigens: 1132
      - HLA Antigens: 8934
        HLA-D Antigens: 238
        HLA-DR Antigens: 5477
        HLA-DR beta-Chains: 64
        HLA-DRB1 Chains: 2199
        HLA-DRB1*04:02 antigen: 12
      - Histocompatibility Antigens Class II: 2170
        HLA-D Antigens: 238
        HLA-DR Antigens: 5477
        HLA-DR beta-Chains: 64
        HLA-DRB1 Chains: 2199
        HLA-DRB1*04:02 antigen: 12

Experts

1.	Behrens, Marshall: 2 articles (11/2014 - 10/2003)
2.	David, Chella S: 2 articles (11/2014 - 10/2003)
3.	Hertl, Michael: 2 articles (11/2014 - 03/2004)
4.	Luthra, Harvinder: 2 articles (11/2014 - 10/2003)
5.	Taneja, Veena: 2 articles (11/2014 - 10/2003)
6.	Bäcklund, Johan: 1 article (11/2014)
7.	Eming, Rüdiger: 1 article (11/2014)
8.	Feliciani, Claudio: 1 article (11/2014)
9.	Hennerici, Tina: 1 article (11/2014)
10.	Holmdahl, Rikard: 1 article (11/2014)

Related Diseases

1.	Rheumatoid Arthritis 04/01/1997 - "Critical residues on HLA-DRB10402 HV3 peptide for HLA-DQ8-restricted immunogenicity: implications for rheumatoid arthritis predisposition." 02/01/2003 - "Can hepatitis C virus infection and interferon-alpha undo the HLA-DRB10402/DQB10302 protection against rheumatoid arthritis?" 11/01/2014 - "HLA-DRB10401 expression in humans has been associated with a predisposition to developing rheumatoid arthritis (RA) and collagen-induced arthritis (CIA), while HLA-DRB1*0402 is not associated with susceptibility. "
2.	Infections 02/01/2003 - "Can hepatitis C virus infection and interferon-alpha undo the HLA-DRB10402/DQB10302 protection against rheumatoid arthritis?"
3.	Pemphigus (Pemphigus Vulgaris) 08/01/2011 - "HLA-DRB104:02, DRB108:04 and DRB114 alleles associated to pemphigus vulgaris in southeastern Brazilian population." 04/01/2007 - "HLA-DRB10402 haplotypes without DQB10302 in Venezuelan patients with pemphigus vulgaris." 01/01/1984 - "Probably HLA-Dw10 predisposes for pemphigus vulgaris." 01/01/1984 - "Is predisposition to pemphigus vulgaris in Jewish patients mediated by HLA-Dw10 and DR4?" 03/15/2004 - "Peptide DG3(96-112), and to a lesser extent DG3(250-266), was recognized by the majority of T cells from patients and healthy donors in association with HLA-DRB10402 and DQB1*0503 which were prevalent in the pemphigus patients and Dsg3-responsive healthy donors. "
4.	Epidermolysis Bullosa Acquisita (Acquired Epidermolysis Bullosa) 11/04/2023 - "Our results summarized the risk alleles that are identified in the literature, together with certain known protective alleles: in the pemphigus group, alleles HLA-DQB10503 and HLA-DRB10402 are most commonly associated with disease; in the pemphigoid group, the most studied allele is HLA-DQB1*0301; in epidermolysis bullosa acquisita, few genetic studies are available; in dermatitis herpetiformis, the association with haplotypes HLA-DQ2 and HLA-DQ8 is strongly established; finally, in linear IgA bullous disease, specific HLA alleles may be responsible for pediatric presentations. "
5.	Bullous Pemphigoid (Pemphigoid) 11/04/2023 - "Our results summarized the risk alleles that are identified in the literature, together with certain known protective alleles: in the pemphigus group, alleles HLA-DQB10503 and HLA-DRB10402 are most commonly associated with disease; in the pemphigoid group, the most studied allele is HLA-DQB1*0301; in epidermolysis bullosa acquisita, few genetic studies are available; in dermatitis herpetiformis, the association with haplotypes HLA-DQ2 and HLA-DQ8 is strongly established; finally, in linear IgA bullous disease, specific HLA alleles may be responsible for pediatric presentations. "

Related Drugs and Biologics

1.	Interferon-alpha (Interferon Alfa)
2.	HLA-DQ8 antigen
3.	Immunoglobulin A (IgA)
4.	HLA-DQB1 antigen (HLA DQB1)
5.	Peptides (Polypeptides)
6.	HLA-DRB1 Chains (HLA DRB1)
7.	Desmoglein 3
8.	Immunodominant Epitopes
9.	Immunoglobulin G (IgG)
10.	Clozapine (Clozaril)