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Immunoglobulin G (IgG)

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The major immunoglobulin isotype class in normal human serum. There are several isotype subclasses of IgG, for example, IgG1, IgG2A, and IgG2B.
Also Known As:
IgG; IgG1; IgG3; Allerglobuline; IgG(T); IgG2; IgG2A; IgG2B; IgG4; Immunoglobulin GT; Polyglobin; 7S Gamma Globulin; GT, Immunoglobulin; Gamma Globulin, 7S
Networked: 34309 relevant articles (1234 outcomes, 2758 trials/studies) for this Bio-Agent, Comments

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Bio-Agent Context: Research Results

Experts

1. Hashimoto, Takashi: 24 articles (11/2012 - 01/2002)
2. Amagai, Masayuki: 23 articles (01/2012 - 09/2002)
3. Lennon, Vanda A: 22 articles (10/2012 - 09/2002)
4. Yuki, Nobuhiro: 22 articles (07/2012 - 01/2002)
5. Pittock, Sean J: 18 articles (09/2012 - 05/2003)
6. Hamano, Hideaki: 17 articles (09/2012 - 04/2002)
7. Itoh, Kyogo: 17 articles (02/2009 - 03/2002)
8. Kawa, Shigeyuki: 16 articles (09/2012 - 04/2002)
9. Wingerchuk, Dean M: 13 articles (09/2012 - 12/2004)
10. Lucchinetti, Claudia F: 13 articles (01/2012 - 05/2003)

Related Diseases

1. Infection
03/01/1990 - "Protection against infection correlated with rotavirus antibody, most significantly (P = .005) serum rotavirus IgG. In this study, 20 previously challenged subjects were reinoculated with the same virus 9-12 months after their initial challenge. "
01/23/2006 - "The B cell-deficient mice displayed impaired T cell priming and dramatically reduced IFN-gamma production, and these deficits were normalized by infection with IgG-opsonized parasites. "
01/01/1998 - "In pregnant women, measurement of the IgG avidity may help to date a HCMV infection, an AI > 65% highly suggests a past infection while an AI < 50% corresponds to a recent primary infection."
08/01/1990 - "High-dose intravenous immunoglobulin therapy is highly effective in PRCA associated with parvovirus B19 infections and impaired IgG-antibody response. "
01/01/2007 - "This review highlights findings from international studies and demonstrates that: (i) SCIG therapy is safe, with very few adverse effects; (ii) the therapy can be used for patients with previous adverse effects to intravenous administration of IgG; (iii) the therapy leads to high serum IgG levels and good protection against infections; (iv) the therapy facilitates home therapy, as the infusion technique is easy for children, adults and elderly people to learn and there is no need for venous access; (v) SCIG home therapy leads to significantly improved life situations for the patients; (vi) the SCIG home therapy regimen in particular reduces the costs of treatment."
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2. Neoplasms (Cancer)
3. Malaria
4. Proteinuria
5. Hypersensitivity (Allergy)

Related Drugs and Biologics

1. Immunoglobulin G (IgG)
2. Antibodies
3. Immunoglobulin M (IgM)
4. Immunoglobulin A (IgA)
5. Antigens
6. Immunoglobulins (Immunoglobulin)
7. Immunoglobulin E (IgE)
8. Antigen-Antibody Complex (Immune Complex)
9. Intravenous Immunoglobulins (IVIG)
10. Autoantibodies

Related Therapies and Procedures

1. Heterologous Transplantation (Xenotransplantation)
2. Transplants (Transplant)
3. Immunotherapy
4. Drug Therapy (Chemotherapy)
5. Radioimmunotherapy

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