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MUC1 tandem repeat peptide

synthetic oligopeptide fragment of Ca-15-3 Antigen; candidate for cancer vaccine; has been sequenced

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Glycoproteins: 24834
    - Membrane Glycoproteins: 2252
      - Mucin-1: 3087
        MUC1 tandem repeat peptide: 2
    - Mucoproteins: 203
      - Mucins: 10505
        Mucin-1: 3087
        MUC1 tandem repeat peptide: 2
  - Membrane Proteins: 10078
    - Membrane Glycoproteins: 2252
      - Mucin-1: 3087
        MUC1 tandem repeat peptide: 2
- Peptides: 82426
  - Peptide Fragments: 373
    - MUC1 tandem repeat peptide: 2
Carbohydrates: 22023
- Glycoconjugates: 1353
  - Glycoproteins: 24834
    - Membrane Glycoproteins: 2252
      - Mucin-1: 3087
        MUC1 tandem repeat peptide: 2
    - Mucoproteins: 203
      - Mucins: 10505
        Mucin-1: 3087
        MUC1 tandem repeat peptide: 2
Biological Factors: 2472
- Biomarkers: 240291
  - Tumor Biomarkers: 15272
    - Carbohydrate Tumor-Associated Antigens: 355
      - Mucin-1: 3087
        MUC1 tandem repeat peptide: 2
- Antigens: 143924
  - Epitopes: 19548
    - Carbohydrate Tumor-Associated Antigens: 355
      - Mucin-1: 3087
        MUC1 tandem repeat peptide: 2
  - Neoplasm Antigens: 6217
    - Carbohydrate Tumor-Associated Antigens: 355
      - Mucin-1: 3087
        MUC1 tandem repeat peptide: 2

Related Diseases

1.	Neoplasms (Cancer) 01/01/1999 - "Sera from mice that rejected PancO2-MUC1 (tumor-immune mice) showed no detectable IgG1 and IgM titers against the MUC1 tandem-repeat peptide, whereas mice with progressive tumor growth had significant titers of IgG1 and IgM specific for MUC1. "
2.	Breast Neoplasms (Breast Cancer) 07/15/1994 - "The data presented here show that acceptor substrate specificity of the UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase detected in lysates of pancreatic and breast tumor cell lines is identical and is limited to some but not all threonines in the MUC1 tandem repeat peptide sequence. "

Related Drugs and Biologics

1.	Immunoglobulin M (IgM)
2.	Immunoglobulin G (IgG)
3.	Polypeptide N-acetylgalactosaminyltransferase