scutebarbatine A

has antineoplastic activity; isolated from Scutellaria barbata; structure in first source

Networked: 4 relevant articles (0 outcomes, 0 trials/studies)

1.	Hepatocellular Carcinoma (Hepatoma) 05/01/2021 - "Scutebarbatine A induces cytotoxicity in hepatocellular carcinoma via activation of the MAPK and ER stress signaling pathways." 06/01/2023 - "Scutebarbatine A (SBT-A), a diterpenoid alkaloid, has exerted cytotoxicity on hepatocellular carcinoma cells in our previous works. "
2.	Neoplasms (Cancer) 01/01/2022 - "Scutebarbatine A is a new neo-Clerodane Diterpenoid Alkaloids from Scutellaria barbata, which has many pharmacological effects, such as anti-tumor, antibacterial, and anti-inflammatory. "
3.	Carcinoma (Carcinomatosis) 06/25/2014 - "In vitro and in vivo antitumor activity of scutebarbatine A on human lung carcinoma A549 cell lines."
4.	Breast Neoplasms (Breast Cancer) 06/01/2023 - "Scutebarbatine A induces ROS-mediated DNA damage and apoptosis in breast cancer cells by modulating MAPK and EGFR/Akt signaling pathway."