zhenshu tiaozhi formula

composed of Citri sarcodactylis fructus, Ligustri lucidi fructus, Salviae miltiorrhizae radix et rhizoma, Notoginseng radix et rhizoma, Coptidis rhizoma, Atractylodis macrocephalae rhizoma, Cirsii japonici herba et radix and Eucommiae cortex

Also Known As:

Networked: 43 relevant articles (11 outcomes, 19 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Guo, Jiao: 22 articles (07/2022 - 08/2010)
2.	Rong, Xianglu: 11 articles (07/2022 - 01/2018)
3.	Wang, Lexun: 7 articles (04/2022 - 01/2021)
4.	Bei, Weijian: 7 articles (06/2021 - 02/2012)
5.	Zhang, Yue: 5 articles (07/2022 - 01/2022)
6.	Diao, Hongtao: 4 articles (07/2022 - 01/2022)
7.	Shao, Xiaoqi: 4 articles (07/2022 - 01/2022)
8.	Yan, Meiling: 4 articles (07/2022 - 01/2022)
9.	Luo, Duosheng: 4 articles (01/2020 - 02/2012)
10.	Lan, Tian: 3 articles (06/2022 - 01/2021)

Related Diseases

1.	Fibrosis (Cirrhosis) 01/01/2022 - "Therefore, this study was designed to investigate the effects and potential mechanisms of FTZ in treating cardiac fibrosis. " 11/15/2022 - "To determine the protective roles and mechanism of FTZ in mouse renal injury and fibrosis under hyperuricemic condition. " 01/01/2022 - "Furthermore, FTZ treatment reduced hepatic inflammatory cell infiltration and fibrosis in mice. " 01/01/2022 - "These findings indicated the therapeutic potential of FTZ in treating cardiac fibrosis." 01/01/2022 - "Furthermore, FTZ downregulated the expression of TGFβ1, p-smad2, and p-smad3 and inhibited the TGFβ1-Smad2/3 pathway in the setting of cardiac fibrosis. "
2.	Cardiomegaly (Heart Hypertrophy) 04/01/2022 - "The aim of this study is to evaluate the protective effects of FTZ on cardiac hypertrophy and determine the underlying mechanisms. " 04/01/2022 - "Collectively, these findings indicate that FTZ is a protective factor for cardiac hypertrophy due to its regulation of the miR-214-SIRT3 axis, which suggests that FTZ may be a therapeutic target for cardiac hypertrophy." 04/01/2022 - "According to our findings, FTZ alleviated cardiac hypertrophy in mice and cell models. " 04/01/2022 - "TAC was utilized to establish a cardiac hypertrophy animal model, and FTZ was given via gavage for four weeks. " 04/01/2022 - "However, the effects of FTZ on cardiac hypertrophy remain unclear. "
3.	Inflammation (Inflammations) 01/01/2022 - "In summary, FTZ ameliorates NASH by inhibiting gut inflammation, improving intestinal barrier function, and modulating intestinal microbiota composition." 08/30/2022 - "We concluded that FTZ prevents renal injury of DM-CHD through activating anti-oxidative capacity to reduce apoptosis and inhibiting inflammation, which may be a new candidate for DKD treatment." 07/12/2022 - "Enrichment analyses indicated that the inhibitory effects of FTZ may primarily involve the regulation of inflammation, osteoclastogenesis, as well as TNF-α signaling pathway. " 05/01/2021 - "FTZ has a protective effect against myocardial injury in DM-CHD by inhibiting inflammation and activating the PI3K/AKT signaling pathway." 01/01/2021 - "Pathway and functional enrichment analyses showed that FTZ mainly regulates inflammation-related pathways, including MAPK and PI3K-AKT signaling pathways. "
4.	Hyperlipidemias (Hyperlipidemia) 01/01/2020 - "This study aimed to reveal the relationship between gut microbiota and the metabolome at different ages, as well as the anti-aging effect of FTZ, which is an effective clinical prescription for the treatment of hyperlipidemia and diabetes. " 08/01/2023 - "FTZ was proposed by Professor Guo Jiao and is used for the clinical treatment of hyperlipidemia. " 10/01/2014 - "Among the eight herbs in prescription FTZ, Rhizoma Coptidis (RC) plays the most important role in whole effect from FTZ on hyperlipidemia related disease. " 10/01/2014 - "Our goal in this study aims to explain the polypharmacological mechanism at the molecular level responsible for the effectiveness of a traditional Chinese medicine (TCM) prescription FTZ to treat hyperlipidemia and related disease. " 01/01/2021 - "Long-Term Effect of Zhenzhu Tiaozhi Capsule (FTZ) on Hyperlipidemia: 2-Year Results from a Retrospective Study Using Electronic Medical Records."
5.	Non-alcoholic Fatty Liver Disease 06/28/2021 - "Network pharmacology was supported by experimental studies, which indicated that FTZ has demonstrated therapeutic benefits in T2DM and NAFLD by regulating the PI3K-AKT and HIF-1α signaling pathways." 06/28/2021 - "To investigate the pharmacological efficacy and mechanism of FTZ in the treatment of T2DM accompanied by NAFLD. " 06/28/2021 - "Because of the complexity of the chemical constituents of Chinese herbal formulas, the holistic pharmacological mechanism of FTZ acting on type 2 diabetes mellitus (T2DM) and nonalcoholic fatty liver disease (NAFLD) remains unclear. " 01/01/2018 - "NLRP3 Inflammasome Formation and Activation in Nonalcoholic Steatohepatitis: Therapeutic Target for Antimetabolic Syndrome Remedy FTZ." 06/28/2021 - "Animal experiments showed that FTZ treatment significantly reduced the serum levels of TG, TC, LDL-C and FBG, increased serum levels of HDL-C, ameliorated systemic insulin resistance (IR), and attenuated liver damage in minipigs with T2DM and NAFLD. "

Related Drugs and Biologics

1.	fufang-zhenzhu-tiaozhi
2.	Inflammasomes
3.	Capsules (Microcapsules)
4.	Lipids
5.	Cytokines
6.	Messenger RNA (mRNA)
7.	Sirtuin 3
8.	Streptozocin (Streptozotocin)
9.	Collagen
10.	6-methyladenine

Related Therapies and Procedures

1.	Chinese Traditional Medicine (Traditional Chinese Medicine)
2.	Aftercare (After-Treatment)
3.	Oral Administration