Abstract | AIM: SUBJECTS AND METHODS: RESULTS: There were direct correlations between the content of BNP and that of NT-proBNP) in all CSPs in the patients from both groups. The study group showed a significantly greater weight loss, which was accompanied by a more pronounced reduction in systolic pulmonary artery pressure, pulmonary venous hypertension, hydrothorax elimination, decreased liver size, lower plasma aldosterone concentration, decreased heart size, and higher left ventricular ejection fraction (LVEF). The study group displayed a steady-state reduction in the plasma concentrations of both BNP and NT-proBNP, significant inverse correlations between the lower BNP level and the higher LVEF throughout the follow-up. CONCLUSION: Extracorporeal dehydration techniques are more effective that intravenous diuretics. The direct correlations between the content of BNP and that of NT-proBNP and between the change in their concentrations during treatment assume the capacity and objectification of diagnosing CHF and its degree, by determining only one of the types of BNP.
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Authors | E A Tabak'ian, A Iu Zaruba, A N Rogoza, D M Ataullakhanova, V V Kukharchuk |
Journal | Terapevticheskii arkhiv
(Ter Arkh)
Vol. 82
Issue 8
Pg. 24-9
( 2010)
ISSN: 0040-3660 [Print] Russia (Federation) |
PMID | 20873241
(Publication Type: Clinical Trial, English Abstract, Journal Article)
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Chemical References |
- Diuretics
- Peptide Fragments
- pro-brain natriuretic peptide (1-76)
- Natriuretic Peptide, Brain
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Topics |
- Adult
- Aged
- Aged, 80 and over
- Chronic Disease
- Diuretics
(administration & dosage, therapeutic use)
- Female
- Heart Failure
(blood, drug therapy, physiopathology, therapy)
- Hemofiltration
(methods)
- Humans
- Kidney
(drug effects, physiopathology)
- Kidney Function Tests
- Male
- Middle Aged
- Natriuretic Peptide, Brain
(blood)
- Peptide Fragments
(blood)
- Treatment Outcome
- Ultrafiltration
(methods)
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