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Furosemide (Lasix)

A benzoic-sulfonamide-furan. It is a diuretic with fast onset and short duration that is used for EDEMA and chronic RENAL INSUFFICIENCY.

Also Known As:

Lasix; Errolon; Frusemid; Furanthril; Furantral; Furosemide Monohydrochloride; Furosemide Monosodium Salt; Fusid; Salix (brand of furosemide); Frusemide; Fursemide; Benzoic acid, 5-(aminosulfonyl)-4-chloro-2-((2-furanylmethyl)amino)-

Networked: 3148 relevant articles (215 outcomes, 363 trials/studies) for this Drug, Comments

Relationship Network

Drug Context: Research Results

Experts

1.	Paterna, Salvatore: 4 articles (09/2012 - 03/2003)
2.	Parrinello, Gaspare: 4 articles (09/2012 - 03/2003)
3.	Di Pasquale, Pietro: 4 articles (09/2012 - 03/2003)
4.	Bagga, Arvind: 4 articles (03/2012 - 08/2004)
5.	Nishino, T: 4 articles (01/2002 - 06/2000)
6.	Seo, Toru: 3 articles (06/2012 - 03/2003)
7.	Sakagami, Masafumi: 3 articles (06/2012 - 03/2003)
8.	Hari, Pankaj: 3 articles (03/2012 - 04/2009)
9.	Chen, Horng H: 3 articles (03/2011 - 04/2004)
10.	Chalasani, N: 3 articles (10/2010 - 01/2001)

Related Diseases

1.	Heart Failure 08/01/1996 - "In a randomized crossover study we compared the efficacy of a continuous infusion of high dose furosemide (mean daily dosage 690 mg, range 250 to 2,000) versus a single bolus injection of an equal dose in 20 patients with severe heart failure. " 08/01/1996 - "The efficacy of high dose furosemide as a continuous infusion was compared with a bolus injection of equal dose in patients with severe heart failure. " 08/01/1996 - "Diuretic efficacy of high dose furosemide in severe heart failure: bolus injection versus continuous infusion." 10/01/1990 - "High dose furosemide was effective for rapid removal of excess water and salt in "furosemide-resistant" congestive heart failure. " 04/01/2012 - "This paper reports on a pilot study that investigated whether intravenous (i.v.) furosemide administered on a cardiology day ward for three successive days was effective in improving the symptoms of patients with fluid overload and chronic heart failure. " Order ALL the reference details at left...
2.	Hypertension (High Blood Pressure) 04/01/2000 - "Thus, these data did not support the contention that administration of furosemide at intervals shorter than 4 h before exercise is more effective in attenuating exercise-induced pulmonary capillary or venous hypertension in Thoroughbred horses." 08/01/2011 - "Moreover, the administration of furosemide in vivo decreased the blood pressure and increased the urine output and natriuresis in MHS rats demonstrating the actual involvement of NKCC2 activity in the pathogenesis of hypertension in this strain of rats. " 05/01/2010 - "On admission, he developed pulmonary oedema from systolic hypertension which was controlled by ventilatory support, nitroglycerine and furosemide. " 12/01/2008 - "Ang II-dependent hypertension increased furosemide-sensitive oxygen consumption (26.2+/-1.0% versus 36.6+/-1.2% of total oxygen consumption; P<0.01). " 04/01/2002 - "The present results indicate that the diagnosis of salt-sensitive hypertension should be based on the BP response to changes in dietary salt intake, while BP response to saline and furosemide administration leads to a systematic misclassification of more than 50% of patients, even using different cutpoints for changes in BP." Order ALL the reference details at left...
3.	Asthma (Bronchial Asthma) 12/01/1995 - "We determined whether chronic administration of furosemide aerosol would be beneficial for the treatment of asthma. " 10/19/1989 - "Whether inhaled furosemide might be useful in the treatment of allergic asthma is uncertain and will require further study." 06/01/2004 - "The clinical efficacy of inhalatory furosemide (Fu) has been extensively studied in bronchial asthma patients but there are only a few studies addressing its action on cells participating in the underlying inflammatory process. " 07/01/2005 - "To investigate the efficacy of nebulized furosemide in children with moderate asthma exacerbations. " 07/01/2005 - "Efficacy of nebulized furosemide in children with moderate attack of asthma." Order ALL the reference details at left...
4.	Edema 04/01/2007 - "Meta analysis showed that dextran-40 together with furosemide was effective for nephrotic edema. " 07/01/1984 - "Our data suggest the possibility that, before decreasing edema, furosemide improved shunt through pulmonary vascular effects by preferential perfusion of nonflooded alveolar units." 04/01/2005 - "In short-term studies, furosemide reduces edema, reduces hospitalizations, and improves exercise capacity in the setting of systolic dysfunction (strength of recommendation [SOR]: B, based upon low-quality randomized controlled trials). " 03/01/1987 - "A double-blind cross-over randomized clinical study with two different brands of furosemide was carried out in seven patients with edema of renal origin. " 03/01/1987 - "Comparative bioequivalence study of furosemide in patients with edema of renal origin." Order ALL the reference details at left...
5.	Ascites 04/01/2012 - "Use of a short continuous furosemide infusion can achieve a FENa of 1% or greater in patients with cirrhotic ascites and may be safe and efficacious for diuresis, meriting further study." 12/01/2005 - "This study shows that HRS as defined by the International Ascites Club can be treated by albumin administration alone or with furosemide given according to the patient's specific need using CVP." 12/01/1967 - "Studies on furosemide: an effective oral saludiuretic for bilharzial ascites." 10/25/1965 - "[Clinical trials of a new salidiuretic, furosemide, in the treatment of cirrhotic ascites. " 04/01/2012 - "We conducted a retrospective case series of patients admitted for management of ascites who received intravenous furosemide by continuous infusion in ascites management. " Order ALL the reference details at left...

Related Drugs and Biologics

1.	Spironolactone (Aldactone)
2.	torsemide (torasemide)
3.	Captopril (Capoten)
4.	Diuretics
5.	Creatinine
6.	Sodium
7.	Digoxin (Digitek)
8.	Dopamine (Intropin)
9.	Enalapril
10.	Glycerol (Glycerine)

Related Therapies and Procedures

1.	Oral Administration
2.	Aftercare (After-Treatment)
3.	Fluid Therapy (Oral Rehydration Therapy)
4.	Intravenous Infusions
5.	Artificial Respiration (Mechanical Ventilation)

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