A transmembrane domain-containing matrix metalloproteinase. It is synthesized as an inactive zymogen that is activated by the action of PROPROTEIN CONVERTASES such as FURIN. Matrix metalloproteinase 14 plays a direct role in the cleavage of proteins in the pericellular environment. In addition, it can function indirectly by enzymatically activating the proprotein form of MATRIX METALLOPROTEINASE 15.
Also Known As:
MT1-MMP; Membrane-Type Matrix Metalloproteinase 1; MMP-14 Metalloproteinase; MMP-X1 Protein; MMP14 Metalloproteinase; MT-MMP-1; MT1-Matrix Metalloproteinase; Membrane-Type 1 Matrix Metalloproteinase; MMP 14 Metalloproteinase; MMP X1 Protein; MT1 Matrix Metalloproteinase; Membrane Type 1 Matrix Metalloproteinase; Membrane Type Matrix Metalloproteinase 1; Metalloproteinase 14, Matrix; Metalloproteinase, MMP-14; Metalloproteinase, MMP14; Metalloproteinase, MT1-Matrix