Transcranial Magnetic Stimulation

A technique that involves the use of electrical coils on the head to generate a brief magnetic field which reaches the CEREBRAL CORTEX. It is coupled with ELECTROMYOGRAPHY response detection to assess cortical excitability by the threshold required to induce MOTOR EVOKED POTENTIALS. This method is also used for BRAIN MAPPING, to study NEUROPHYSIOLOGY, and as a substitute for ELECTROCONVULSIVE THERAPY for treating DEPRESSION. Induction of SEIZURES limits its clinical usage.

Also Known As:

Networked: 6057 relevant articles (708 outcomes, 1428 trials/studies)

Relationship Network

Therapy Context: Research Results

Experts

1.	Daskalakis, Zafiris J: 113 articles (06/2022 - 02/2002)
2.	Pascual-Leone, Alvaro: 103 articles (01/2022 - 07/2002)
3.	Fitzgerald, Paul B: 87 articles (01/2022 - 02/2002)
4.	Fregni, Felipe: 74 articles (12/2021 - 05/2004)
5.	Blumberger, Daniel M: 67 articles (06/2022 - 03/2010)
6.	Langguth, Berthold: 66 articles (02/2022 - 10/2003)
7.	Zangen, Abraham: 52 articles (02/2022 - 02/2007)
8.	Abo, Masahiro: 47 articles (12/2021 - 01/2010)
9.	Rothwell, John C: 42 articles (01/2020 - 08/2002)
10.	George, Mark S: 41 articles (03/2022 - 02/2003)

Related Diseases

1.	Stroke (Strokes) 04/01/2022 - "Previous studies have revealed that low frequency repeated transcranial magnetic stimulation (rTMS) on the contralesional primary motor cortex (cM1) is less effective in severe stroke patients with poor neural structural reserve than in patients with highly reserved descending motor pathway. " 11/22/2023 - "This study aimed to evaluate the efficacy of repetitive transcranial magnetic stimulation (rTMS) in treating lower limb motor dysfunction after stroke and explore the optimal stimulation parameters. " 02/01/2011 - "Although functional imaging studies suggest that recruitment of contralesional areas hinders optimal functional reorganization in patients with aphasic stroke, only limited evidence is available on the efficacy of noninvasive brain stimulation such as repetitive transcranial magnetic stimulation aimed at suppression of contralateral overactivation. " 01/01/2023 - "This study was to investigate whether high frequency repetitive transcranial magnetic stimulation (HF-rTMS) combined with cervical nerve root magnetic stimulation more effectively ameliorates upper limb motor function in stroke patients. " 04/01/2021 - "Despite high incidence of depression after stroke, few trials have investigated the therapeutic efficacy of repetitive transcranial magnetic stimulation (rTMS). "
2.	Major Depressive Disorder (Major Depressive Disorders) 03/01/2023 - "One of the most effective treatments for drug-resistant Major depressive disorder (MDD) patients is repetitive transcranial magnetic stimulation (rTMS). " 09/01/2021 - "Repetitive Transcranial Magnetic Stimulation (rTMS) is an effective treatment for Major Depressive Disorder (MDD), but therapeutic benefit is highly variable. " 01/01/2018 - "Background: High-frequency (HF) repetitive transcranial magnetic stimulation (rTMS) over the left dorsolateral prefrontal cortex (L-DLPFC) is the most widely applied treatment protocol for major depressive disorder (MDD), while low-frequency (LF) rTMS over the right DLPFC (R-DLPFC) also exhibits similar, if not better, efficacy for MDD. " 01/01/2023 - "Repetitive transcranial magnetic stimulation (rTMS) and intermittent theta burst stimulation (iTBS) have been proven effective non-invasive treatments for patients with drug-resistant major depressive disorder (MDD). " 01/01/2021 - "Background: Repetitive transcranial magnetic stimulation (rTMS) has been proven to be safe and effective in treating major depressive disorder (MDD). "
3.	Treatment-Resistant Depressive Disorder 01/01/2022 - "Transcranial magnetic stimulation (TMS) is a proven intervention for treatment-resistant depression in younger adults but the efficacy of TMS to treat depressed older adults is still unclear. " 04/01/2011 - "Treatment-resistant depression is a severely disabling disorder with no proven treatment options; novel treatment methods, such as repetitive transcranial magnetic stimulation (rTMS) can be used as augmentation to ongoing pharmacotherapy or as a solitary method of treatment. " 01/01/2023 - "The aim of this study is to compare the efficacy of high-frequency repetitive transcranial magnetic stimulation (HF-rTMS) to left dorsolateral prefrontal cortex (DLPFC) with that of pharmacological augmentation strategies in unipolar non-psychotic treatment-resistant depression. " 11/01/2020 - "Repetitive transcranial magnetic stimulation (rTMS) is a treatment option for treatment resistant depression (TRD) with response and remission rates in open-label studies being as high as 58% and 37% respectively. " 01/01/2019 - "Clinical trials and meta-analyses have demonstrated the efficacy of high-frequency repetitive transcranial magnetic stimulation (rTMS) over the left prefrontal cortex in treatment-resistant depression. "
4.	Schizophrenia (Dementia Praecox) 01/01/2022 - "Repetitive transcranial magnetic stimulation is a noninvasive, painless, safe, efficacious, and economical physical therapy measure that has achieved good results in the treatment of schizophrenia. " 01/01/2018 - "Efficacy of high-frequency repetitive transcranial magnetic stimulation on PANSS factors in schizophrenia with predominant negative symptoms - Results from an exploratory re-analysis." 08/30/2003 - "Repetitive transcranial magnetic stimulation (rTMS) can be beneficial in schizophrenia, possibly through a reversal of pre-treatment hypofrontality. " 11/15/1999 - "The aim of this study was to extend our previous work on the therapeutic efficacy of repetitive transcranial magnetic stimulation (rTMS) in major depression to patients with schizophrenia. " 01/01/1998 - "This study was designed to evaluate the potential efficacy of repetitive transcranial magnetic stimulation (rTMS) at low-frequency in patients with major depression and schizophrenia. "
5.	Parkinson Disease (Parkinson's Disease) 04/01/2009 - "Repetitive transcranial magnetic stimulation (rTMS) has shown promising results in treating Parkinson's disease (PD), but the best values for rTMS parameters are not established. " 01/01/2020 - "Background: Pilot open-label application of high-frequency repetitive transcranial magnetic stimulation (rTMS) with H-coil in Parkinson's Disease (PD) have shown promising results. " 07/01/2008 - "To obtain preliminary data on the effects of high-intensity exercise on functional performance in people with Parkinson's disease (PD) relative to exercise at low and no intensity and to determine whether improved performance is accompanied by alterations in corticomotor excitability as measured through transcranial magnetic stimulation (TMS). " 05/15/2007 - "Repeated session of repetitive transcranial magnetic stimulation (rTMS) over motor cortex have been reported to produce significant improvement of motor performance in patients with parkinson's disease (PD). " 01/01/1999 - "Lack of clinical improvement in patients with Parkinson's disease after low and high frequency repetitive transcranial magnetic stimulation."

Related Drugs and Biologics

1.	salicylhydroxamic acid (SHAM)
2.	Antidepressive Agents (Antidepressants)
3.	Biomarkers (Surrogate Marker)
4.	Levodopa (L Dopa)
5.	Ketamine
6.	Type A Botulinum Toxins (Botox)
7.	Therapeutic Uses
8.	Analgesics (Analgesic Drugs)
9.	Anticonvulsants (Antiepileptic Drugs)
10.	Fluoxetine (Prozac)

Related Therapies and Procedures

1.	Transcranial Direct Current Stimulation
2.	Therapeutics
3.	Vagus Nerve Stimulation
4.	Occupational Therapy (Therapy, Occupational)
5.	Deep Brain Stimulation