Hormonally active polypeptides that can induce the transformed phenotype when added to normal, non-transformed cells. They have been found in culture fluids from retrovirally transformed cells and in tumor-derived cells as well as in non-neoplastic sources. Their transforming activities are due to the simultaneous action of two otherwise unrelated factors, TRANSFORMING GROWTH FACTOR ALPHA and TRANSFORMING GROWTH FACTOR BETA.
Also Known As:
Transforming Growth Factor; Factor, Transforming Growth; Factors, Transforming Growth; Growth Factor, Transforming; Growth Factors, Transforming; Animal growth regulators, transforming growth factors