Vanadium

A metallic element with the atomic symbol V, atomic number 23, and atomic weight 50.94. It is used in the manufacture of vanadium steel. Prolonged exposure can lead to chronic intoxication caused by absorption usually via the lungs.

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Networked: 695 relevant articles (39 outcomes, 112 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Chatterjee, Malay: 17 articles (09/2011 - 11/2003)
2.	Crans, Debbie C: 12 articles (01/2021 - 07/2005)
3.	Chatterjee, M: 7 articles (01/2005 - 08/2000)
4.	Olopade, James O: 6 articles (12/2020 - 09/2010)
5.	He, Zhijun: 5 articles (12/2022 - 01/2020)
6.	Ding, Wenjun: 5 articles (05/2022 - 11/2007)
7.	Li, Yuanyuan: 5 articles (01/2021 - 01/2016)
8.	Treviño, Samuel: 5 articles (01/2021 - 01/2016)
9.	Xia, Wei: 5 articles (01/2021 - 01/2016)
10.	Xu, Shunqing: 5 articles (01/2021 - 01/2016)

Related Diseases

1.	Carcinogenesis 11/01/2005 - "It was found that vanadium treatment brought about substantial protection against DMBA-induced mammary carcinogenesis. " 09/01/2000 - "It was found that vanadium treatment brought about a substantial protection against DMBA-induced mammary carcinogenesis. " 02/01/1997 - "Supplementary vanadium also elicited substantial protection against DENA-mediated rat liver carcinogenesis. " 01/01/2005 - "The present study was to gain insight into a putative anticancer effect of vanadium in a rat model of colon carcinogenesis. " 12/01/2007 - "From the results, we anticipate that the carcinogenesis of vanadium to human bronchial cells may result from anti-apoptosis mediated by the NFAT-dependent induction of COX-2, and we also assume that either pro-apoptotic or anti-apoptotic effect in certain type of cells after vanadium exposure may depend on the level of COX-2 induction."
2.	Neoplasms (Cancer) 09/01/2000 - "There was a significant reduction in incidence (P < 0.05), total number, multiplicity (P < 0.01) and size of palpable mammary tumors and delay in mean latency period of tumor appearance (P < 0.001) following vanadium supplementation compared to DMBA control. " 01/01/2018 - "It is appropriate to consider vanadium as a treatment option due to the similarities in some of the metabolic pathways utilized by both diabetes and cancer and therefore is among the few drugs that are effective against more than one disease. " 09/01/2023 - "The studies have reported the G0/G1 phase cell cycle arrest and decreased delta psi m, inducing mitochondrial membrane depolarization in cancer cell lines along with the alterations in the metabolism of the cancer cells upon dosing with the vanadium complexes. " 09/01/2017 - "Various epidemiological and preclinical studies have already established the cancer chemopreventive potential of vanadium. " 05/01/2017 - "Various epidemiological and preclinical studies have already established the cancer chemopreventive potential of vanadium-based compounds. "
3.	Diabetes Mellitus 11/03/2021 - "We recently adopted a vanadium compound bis(ethylmaltolato)-oxidovanadium (IV) (BEOV), which was originally used for curing diabetes mellitus (DM), to treat AD in a mouse model. " 01/01/2020 - "Vanadium) possess an attractive proposition in medicinal treatment of diabetes mellitus. " 01/01/2018 - "Vanadium(IV/V) compounds have been studied as possible metallopharmaceutical drugs against diabetes mellitus. " 01/01/2016 - "New potential drugs based on vanadium are being developed as possible treatments for diabetes mellitus (DM) and its complications. " 01/01/2005 - "[Therapeutic potential of vanadium in treating diabetes mellitus]."
4.	Insulin Resistance 04/01/2008 - "Till today decrease in insulin resistance by vanadium treatment has been mainly attributed to its potential to inhibit PTP-1B, however the present study opens a new dimension in vanadium treatment for diabetes due to its novel role in adipogenesis." 05/01/2016 - "Sea cucumbers are a potential source of natural organic vanadium that may improve insulin resistance. " 01/01/2006 - "In the latter case vanadium treatment may not have totally overcome the insulin resistance seen in these animals." 06/01/2001 - "Effect of vanadium on insulin sensitivity and appetite." 01/01/2008 - "Effect of vanadium on insulin sensitivity in patients with impaired glucose tolerance."
5.	Type 2 Diabetes Mellitus (MODY) 10/01/2003 - "Vanadium has been shown to be beneficial in the oral treatment of animal models of type 1 and type 2 diabetes. " 05/01/2008 - "Selection criteria for inclusion in the review were controlled human trials of vanadium vs. placebo in adults with type 2 diabetes of minimum 2 months duration, and a minimum of 10 subjects per arm. " 03/01/2003 - "Vanadium is currently undergoing clinical trials as an oral drug in patients with noninsulin-dependent diabetes mellitus. " 08/15/2014 - "Our results suggested that plasma vanadium concentrations were inversely associated with newly diagnosed type 2 diabetes in this Chinese population. " 08/15/2014 - "Participants in the highest quartile of plasma vanadium concentration had a notably lower risk of newly diagnosed type 2 diabetes (odds ratio = 0.26, 95% confidence interval: 0.19, 0.35; P < 0.001), compared with persons in the lowest quartile. "

Related Drugs and Biologics

1.	Insulin (Novolin)
2.	Vanadates (Orthovanadate)
3.	Salts
4.	Glucose (Dextrose)
5.	Ions
6.	Dimenhydrinate (DMH)
7.	Zinc
8.	Chromium
9.	Arsenic
10.	Micronutrients

Related Therapies and Procedures

1.	Therapeutics
2.	Injections
3.	Drug Therapy (Chemotherapy)
4.	Oral Administration
5.	Prostheses and Implants (Prosthesis)