GADD45 Proteins

07/01/2014 - "We also highlight recent advances in exploring the tumor suppressive function of GADD45 proteins-triggered cellular senescence."
07/01/2014 - "In this review, we discuss the deregulation and cellular function of GADD45 proteins in the context of cancer development. "
07/01/2014 - "GADD45 proteins: roles in cellular senescence and tumor development."
06/01/2012 - "Emerging functional evidence implies that GADD45 proteins serve as tumor suppressors in response to diverse stimuli, connecting multiple cell signaling modules. "
02/01/2011 - "Recent progress in the identification of molecules that participate in the SAPK pathways, such as GADD45 proteins and Wipl, has provided new insights, not only into the molecular basis of the cellular response to environmental stress, but also into the etiology of human diseases including cancer."

01/01/2022 - "Thus Gadd45 proteins provide excellent targets for leukemia therapy."
01/01/2011 - "Using genetically engineered mouse models and bone-marrow transplantation, evidence has been obtained indicating that Gadd45 proteins can function to either promote or suppress tumor development and leukemia; this is dependent on the molecular nature of the activated oncogene and the cell type, via engagement of different signaling pathways."

01/01/2016 - "It was recently shown that HIV-1 infection induces the expression of GADD45 proteins. "
01/01/2022 - "The last two sections will be on the function of Gadd45 proteins in infection, autoimmunity, and tumor immunology."

06/01/2012 - "GADD45 proteins: central players in tumorigenesis."

01/07/2011 - "The Gadd45 proteins play important roles in growth control, maintenance of genomic stability, DNA repair, and apoptosis. "