CD68 Molecule

A single-pass type 1 transmembrane glycoprotein that localizes to LYSOSOMES; ENDOSOMES; and cell surface CELL MEMBRANES. It is a member of the lysosomal associated membrane glycoprotein family and the scavenger receptor family. The highly glycosylated extracellular domain binds to tissue- and organ-specific LECTINS or SELECTINS.

Also Known As:

Antigen, CD68; Lysosomal Associated Membrane Protein 4; CD68 Antigen; LAMP4 Protein; Lysosomal-Associated Membrane Protein 4; Macrosialin; SCARD1 Protein; Scavenger Receptor Class D, Member 1

Networked: 34 relevant articles (0 outcomes, 3 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Bogie, Jeroen F J: 1 article (11/2022)
2.	Dierckx, Tess: 1 article (11/2022)
3.	Gervois, Pascal: 1 article (11/2022)
4.	Haidar, Mansour: 1 article (11/2022)
5.	Hendriks, Jerome J A: 1 article (11/2022)
6.	Lambrichts, Ivo: 1 article (11/2022)
7.	Loix, Melanie: 1 article (11/2022)
8.	Vangansewinkel, Tim: 1 article (11/2022)
9.	Vanherle, Sam: 1 article (11/2022)
10.	Wolfs, Esther: 1 article (11/2022)

Related Diseases

1.	Portal Hypertension 07/01/2017 - "Histochemical stains (chromatic aniline blue [CAB], Prussian blue [Berlin blue, BBL], periodic acid-Schiff reaction [PAS], diastase-PAS [D‑PAS], reticulin, rhodanine, Victoria blue) and immunohistochemical studies to demonstrate the expression of keratin 7 (cholangiocytes) and macrosialin (CD68; macrophages) as well as electron microscopy are important techniques in the histopathologic analysis of ontogenetic, storage, and metabolic disorders, hepatitis, hepatosplenomegaly, cholestasis, and portal hypertension. "
2.	Hepatitis 07/01/2017 - "Histochemical stains (chromatic aniline blue [CAB], Prussian blue [Berlin blue, BBL], periodic acid-Schiff reaction [PAS], diastase-PAS [D‑PAS], reticulin, rhodanine, Victoria blue) and immunohistochemical studies to demonstrate the expression of keratin 7 (cholangiocytes) and macrosialin (CD68; macrophages) as well as electron microscopy are important techniques in the histopathologic analysis of ontogenetic, storage, and metabolic disorders, hepatitis, hepatosplenomegaly, cholestasis, and portal hypertension. "
3.	Cholestasis 07/01/2017 - "Histochemical stains (chromatic aniline blue [CAB], Prussian blue [Berlin blue, BBL], periodic acid-Schiff reaction [PAS], diastase-PAS [D‑PAS], reticulin, rhodanine, Victoria blue) and immunohistochemical studies to demonstrate the expression of keratin 7 (cholangiocytes) and macrosialin (CD68; macrophages) as well as electron microscopy are important techniques in the histopathologic analysis of ontogenetic, storage, and metabolic disorders, hepatitis, hepatosplenomegaly, cholestasis, and portal hypertension. "
4.	Cholecystitis 12/01/2013 - "The study aimed at quantitative analysis of expression involving markers of mast cells (tryptase), monocytes/macrophages (CD68 molecule) and dendritic cells (S100 protein) in gallbladder mucosa with acute and chronic calculous cholecystitis. "
5.	Intracranial Aneurysm (Cerebral Aneurysm) 02/24/2023 - "The aim of this study was to assess the CD68 antigen levels in cerebral aneurysm (CA) patients compared to a control group at a referral center in Iran. " 02/24/2023 - "CD68 Antigen and Cerebral Aneurysms: A Case-Control Study."

Related Drugs and Biologics

1.	S100 Proteins (S 100 Protein)
2.	Tryptases (Tryptase)
3.	Keratin-7 (Cytokeratin 7)
4.	Rhodanine
5.	Reticulin (Reticular Fiber)
6.	Periodic Acid
7.	Amylases
8.	victoria blue
9.	aniline blue
10.	ferric ferrocyanide (Prussian blue)

Related Therapies and Procedures

1.	Enzyme Replacement Therapy
2.	Hematopoietic Stem Cell Transplantation
3.	Cardiopulmonary Resuscitation (CPR)