Nanovaccines

Vaccines that use NANOPARTICLES as carriers and IMMUNOLOGIC ADJUVANTS.

Also Known As:

Nano Particle Vaccine; Nano Vaccine; Nano-Particle Vaccines; Nano-Vaccines; Nanoparticle Vaccines; Vaccine, Nano-Particle; Vaccine, Nanoparticle; Vaccines, Nano-Particle; Vaccines, Nanoparticle; Nano-Particle Vaccine; Nano-Vaccine; Nanoparticle Vaccine; Nanovaccine

Networked: 600 relevant articles (85 outcomes, 62 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Narasimhan, Balaji: 14 articles (01/2021 - 07/2014)
2.	Kong, Deling: 9 articles (01/2022 - 01/2017)
3.	Zhu, Guizhi: 8 articles (01/2022 - 03/2016)
4.	Zhang, Yu: 7 articles (03/2022 - 01/2019)
5.	Liu, Zhuang: 7 articles (01/2022 - 01/2018)
6.	Renukaradhya, Gourapura J: 7 articles (01/2021 - 01/2017)
7.	Wannemuehler, Michael J: 7 articles (01/2021 - 07/2014)
8.	Zhang, Chuangnian: 6 articles (05/2022 - 01/2017)
9.	Fontana, Flavia: 6 articles (03/2022 - 01/2017)
10.	Santos, Hélder A: 6 articles (03/2022 - 01/2017)

Related Diseases

1.	Neoplasms (Cancer) 10/01/2020 - "Moreover, the nanovaccine combining with anti-PD-L1 results a marked decrease in tumor size and prolonged survival of tumor-bearing mice by decreasing infiltration of regulatory T cells to the tumor lesion. " 01/01/2021 - "The Mn4+-SNPs+GF001 nanovaccine induced strong E7-specific CD8+ T cell responses, leading to remission of established murine HPV16 E7-expressing solid TC-1 tumors and E7-expressing transgenic skin grafts. " 01/01/2022 - "Excitingly, we observed in several murine tumor models that using this nanovaccine alone could elicit robust immune response in vivo and result in superior anti-tumor effects with 50% of mice completely cured. " 11/01/2020 - "Better understanding and improved knowledge of nanomedicines-based delivery approaches and immunostimulatory action, and in-vivo biodistribution would inevitably facilitate the altruistic design of cancer nanovaccine for humankind." 07/21/2023 - "All in all, the studies demonstrated that probiotics formulation can assist to maximize the efficacy of cancer nanovaccines."
2.	Melanoma (Melanoma, Malignant) 01/01/2019 - "Studies using mouse models of subcutaneous melanoma indicated that GNP-LLO91-99 nanovaccines recruite and modulate dendritic cell (DC) function within the tumour, alter tumour immunotolerance inducing melanoma-specific cytotoxic T cells, cause complete remission and improve survival. " 01/01/2023 - "Consequently, the biomimetic nanovaccines outperformed greater prophylactic and therapeutic efficacy than nanovaccines without Pro encapsulation in B16-F10 melanoma mice. " 01/01/2021 - "The FNC-fabricated nanovaccines when combined with anti-CTLA-4 show potency in lymph node targeting, DC antigen presentation, and T cell immune activation, leading to prophylactic and therapeutic efficacy in a melanoma mouse model. " 08/01/2020 - "Our results demonstrated the synergism between Lip-peptide+CpG nanovaccine and anti PD-1 regime, which improved the therapeutic efficacy of PD-1 checkpoint blocker in melanoma mice models." 10/01/2023 - "HA-nanovaccine significantly delayed the growth of B16F10 melanoma and extended survival in both the prophylactic and therapeutic settings (median survival of 22 and 27, respectively, vs 17 days of the untreated group). "
3.	Human Influenza (Influenza) 01/01/2013 - "Immunogenicity and protective efficacy of candidate universal influenza A nanovaccines produced in plants by Tobacco mosaic virus-based vectors." 01/01/2018 - "Improved Titers against Influenza Drift Variants with a Nanoparticle Vaccine." 03/14/2016 - "Combination Nanovaccine Demonstrates Synergistic Enhancement in Efficacy against Influenza." 01/01/2023 - "By using a nanoparticle library approach with this helix-A nanoparticle design, we show that this vaccine nanoparticle construct design could be applicable to different influenza HA subtypes. " 01/01/2022 - "These results provide a proof of concept for the 3MCD-f nanovaccine that might be an ideal candidate for future influenza pandemics."
4.	Infections 09/01/2023 - "Collectively, the gD-based nanoparticle vaccine design appears to be a promising candidate for potent protection against PRV infection." 01/01/2018 - "Altogether our findings show that an intranasally administered nanovaccine can induce immunity within the lungs, similar to what occurs during IAV infections, and thus could prove useful as a strategy for providing "universal" protection against IAV." 01/01/2022 - "These findings reveal the efficacy of nanovaccines mediated subcutis-to-intestine cascade in simultaneously activating cellular and mucosal immune responses against mucosal infections." 01/01/2022 - "Nanovaccines Mediated Subcutis-to-Intestine Cascade for Improved Protection against Intestinal Infections." 01/01/2018 - "Polyanhydride Nanovaccine Induces Robust Pulmonary B and T Cell Immunity and Confers Protection Against Homologous and Heterologous Influenza A Virus Infections."
5.	Neoplasm Metastasis (Metastasis) 01/01/2018 - "Importantly, our studies demonstrate significant reductions in systemic metastasis with the nanoparticle vaccine. " 01/01/2023 - "The nanovaccine 8FNs demonstrate significant therapeutic and prophylactic efficacy against in situ tumor growth, effectively inhibit tumor metastasis, and significantly prolong the survival of tumor-bearing mice. " 11/01/2023 - "Moreover, this nanovaccine is administered to CT26 (hot) and B16F10 (cold) tumor model mice, in which it targeted the primary tumors and induced systemic antitumor immunity to inhibit metastasis. " 11/01/2023 - "Heteroantigen-assembled nanovaccine enhances the polyfunctionality of TILs against tumor growth and metastasis." 10/24/2023 - "Viral nanoparticle vaccines against S100A9 reduce lung tumor seeding and metastasis."

Related Drugs and Biologics

1.	Antigens
2.	Peptides (Polypeptides)
3.	Proteins (Proteins, Gene)
4.	Epitopes
5.	Vaccines
6.	Chitosan
7.	Hemagglutinins (Hemagglutinin)
8.	Nanovaccines
9.	CPG-oligonucleotide
10.	Therapeutic Uses

Related Therapies and Procedures

1.	Immunotherapy
2.	Therapeutics
3.	Drug Therapy (Chemotherapy)
4.	Photochemotherapy (Photodynamic Therapy)
5.	Photothermal Therapy