Maggot Debridement Therapy

Medical use of live MAGGOTS for cleaning non-healing wounds.

Also Known As:

Debridement Therapy, Larval; Debridement Therapy, Maggot; Therapy, Larva; Therapy, Larvae; Therapy, Larval; Therapy, Larval Debridement; Therapy, Maggot; Therapy, Maggot Debridement; Larva Therapy; Larvae Therapy; Larval Debridement Therapy; Larval Therapy; Maggot Therapy

Networked: 331 relevant articles (49 outcomes, 38 trials/studies)

Relationship Network

Therapy Context: Research Results

Therapeutics: 1158551
- Biological Therapy: 6827
  - Maggot Debridement Therapy: 331

Experts

1.	Sherman, Ronald A: 15 articles (01/2022 - 06/2002)
2.	Nigam, Yamni: 7 articles (08/2016 - 11/2004)
3.	Steenvoorde, P: 6 articles (07/2008 - 07/2004)
4.	Cullum, Nicky: 5 articles (08/2015 - 07/2004)
5.	Thomas, S: 5 articles (11/2006 - 01/2000)
6.	Goli, Rasoul: 4 articles (05/2022 - 05/2021)
7.	Polat, Erdal: 4 articles (01/2022 - 09/2018)
8.	Akbarzadeh, Kamran: 4 articles (09/2021 - 11/2016)
9.	Armstrong, David G: 4 articles (10/2020 - 07/2002)
10.	Díaz-Roa, Andrea: 4 articles (01/2018 - 08/2014)

Related Diseases

1.	Wounds and Injuries (Trauma) 12/01/2020 - "Wound treatment with disinfected blowfly larvae (maggot debridement therapy or MDT) has been shown to be highly effective, with multiple studies demonstrating effective debridement, disinfection, and promotion of granulation tissue. " 06/01/2016 - "Larval therapy is a feasible and safe treatment for therapeutic application and, in many cases, the only and the most recommended alternative for difficult healing injuries. " 10/01/2006 - "Maggot therapy is a cheap, safe and highly effective treatment of wounds. " 08/01/2017 - "Maggot therapy is very effective in wound debridement; it is simple to apply and requires very little in the way of resources, costs, or skilled personnel. " 06/01/2006 - "It is now a universally acknowledged fact that maggot therapy can be used successfully to treat chronic, long-standing, infected wounds, which have previously failed to respond to conventional treatment. "
2.	Ulcer 03/01/2003 - "We found larval therapy to effectively debride 86% of the necrotic ulcers, and a single application was clinically beneficial in two-thirds of the patients. " 10/01/2020 - "Maggot debridement therapy (MDT) is effective for ulcer debridement, achieving it in less time than other therapies. " 10/01/2020 - "Maggot debridement therapy (MDT) is effective for ulcer debridement, achieving it in less time than other therapies. " 03/01/2003 - "In conclusion, we found larval therapy to be effective for debriding ulcers, easy to use and well accepted by the patients." 09/01/2023 - "Despite the severity of the ulcer, a combination therapy approach, including surgical debridement, maggot therapy, and negative pressure wound therapy, was implemented, leading to successful healing. "
3.	Diabetic Foot 01/01/2022 - "One hundred twenty-nine patients diagnosed with lower limb ulceration and diabetic foot were enrolled in the study, of which 80 of them met the eligibility criteria for maggot debridement therapy (MDT). " 03/01/2016 - "Maggot debridement therapy promotes diabetic foot wound healing by up-regulating endothelial cell activity." 03/02/1997 - "5 patients with diabetic-foot were treated by maggot therapy. " 09/01/2021 - "The combined use of surgical debridement and maggot therapy is a safe and effective method for improving diabetic foot ulcers and preventing amputation." 09/01/2013 - "To assess the potential efficacy of maggot debridement therapy (MDT) compared with standard care for diabetic foot ulcers (DFUs). "
4.	Leg Ulcer 10/08/2020 - "Safety and efficacy of larval therapy on treating leg ulcers: a protocol for systematic review and meta-analysis." 08/01/2015 - "Patients may hold unrealistic expectations that larval therapy will effect a longed-for cure for their leg ulcer(s) but an absence of healing may lead to feelings of disappointment or despair." 01/01/2006 - "To establish a maggot debridement therapy unit and assess efficacy of this method in chronic conservative non-treatable leg ulcers in patient in whom conventional therapy failed. " 02/01/2003 - "To assess the efficacy of maggot therapy for treating foot and leg ulcers in diabetic patients failing conventional therapy. " 08/01/2021 - "However, further high quality randomised controlled trials, comparing larval therapy to other debridement methods for venous leg ulcers, incorporating the use of compression is required to determine the long term effects of larval therapy."
5.	Foot Ulcer 01/01/2022 - "A microbiological analysis in this non-reference study shows the efficacy of larval therapy for leg and foot ulcers. " 11/01/2021 - "Maggot Debridement Therapy for Chronic Leg and Foot Ulcers: A Review of Randomized Controlled Trials." 04/01/1995 - "The authors illustrated a chronic bilateral plantar foot ulcer of several years' duration that was resistant to all forms of conventional therapy, yet was resolved after 13 1/2 weeks of maggot therapy. "

Related Drugs and Biologics

1.	Hydrogels
2.	Intercellular Signaling Peptides and Proteins (Growth Factors)
3.	Chymotrypsin
4.	Platelet-Derived Growth Factor
5.	Oxygen (Dioxygen)
6.	Streptozocin (Streptozotocin)
7.	Anti-Bacterial Agents (Antibiotics)
8.	Alginates
9.	Silver
10.	Fibroblast Growth Factor 7

Related Therapies and Procedures

1.	Debridement
2.	Therapeutics
3.	Maggot Debridement Therapy
4.	Surgical Amputation (Amputations)
5.	Complementary Therapies (Alternative Medicine)