Protein Subunit Vaccines

Vaccines that contain polypeptide chains, which are derived from specific pathogen's protein subunits.

Also Known As:

Protein Vaccines, Recombinant; Subunit Vaccines, Protein; Vaccine, Peptide; Vaccines, Protein Subunit; Vaccines, Recombinant Protein; Peptide Vaccine; Peptide Vaccines; Recombinant Protein Subunit Vaccines; Recombinant Protein Vaccines; Vaccines, Peptide; Vaccines, Subunit, Protein

Networked: 1297 relevant articles (139 outcomes, 256 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Complex Mixtures: 1906
- Biological Products
  - Vaccines: 124365
    - Subunit Vaccines: 1839
      - Acellular Vaccines: 280
        Protein Subunit Vaccines: 1297

Experts

1.	Itoh, Kyogo: 39 articles (08/2021 - 03/2002)
2.	Yamada, Akira: 27 articles (08/2021 - 09/2002)
3.	Nakatsura, Tetsuya: 24 articles (02/2021 - 05/2011)
4.	Sugiyama, Haruo: 23 articles (02/2022 - 09/2004)
5.	Noguchi, Masanori: 20 articles (12/2017 - 10/2005)
6.	Oji, Yusuke: 18 articles (02/2022 - 09/2004)
7.	Oka, Yoshihiro: 18 articles (02/2022 - 09/2004)
8.	Tsuboi, Akihiro: 18 articles (02/2022 - 09/2004)
9.	Nakamura, Yusuke: 17 articles (01/2022 - 11/2008)
10.	Peoples, George E: 17 articles (11/2021 - 07/2004)

Related Diseases

1.	Neoplasms (Cancer) 05/28/2019 - "Administrations of cancer-specific neoepitopes in the form of synthetic peptide vaccine have been proven effective in both mouse models and human patients. " 01/01/2017 - "Peptide vaccines offer anti-tumor efficacy with very low toxicity. " 11/05/2009 - "We investigated the immunogenicity and efficacy of a synthetic long-peptide vaccine in women with HPV-16-positive, high-grade vulvar intraepithelial neoplasia. " 05/29/2020 - "Intranasal Therapeutic Peptide Vaccine Promotes Efficient Induction and Trafficking of Cytotoxic T Cell Response for the Clearance of HPV Vaginal Tumors." 04/30/2020 - "In this review we will discuss the hurdles that limit efficacy of conventional cancer therapeutic vaccination methods (e.g., peptide vaccines, dendritic cell vaccination). "
2.	Infections 01/01/2015 - "Peptide vaccines have been shown effective in preventing animal infection in some instances, and various formulations are under evaluation for their potential clinical use in humans. " 09/27/1994 - "Further, this peptide vaccine was shown to be effective in preventing infection with a naturally occurring antigenic variant, A/Texas/1/77(H3N2), carrying the same sequence at 127-133 of the HA as Aichi/68 virus. " 07/01/2018 - "Efficacy of recombinant protein vaccines for protection against Nocardia seriolae infection in the largemouth bass Micropterus salmoides." 01/01/2016 - "The Breadth of Synthetic Long Peptide Vaccine-Induced CD8+ T Cell Responses Determines the Efficacy against Mouse Cytomegalovirus Infection." 02/01/2015 - "Two doses of 50 μg of the synthetic PB peptide vaccine provided 100% protection against FMDV infection in guinea pigs, and a single dose of 100 μg provided 60% protection in cattle. "
3.	Melanoma (Melanoma, Malignant) 01/30/2023 - "Peptide Vaccines in Melanoma: Chemical Approaches towards Improved Immunotherapeutic Efficacy." 07/01/2020 - "The motivating application studies regimens that are not defined by doses of a new agent, but rather a peptide vaccine plus novel adjuvants for the treatment of melanoma. " 12/01/2017 - "This design can be applied more broadly to early-phase combination studies, as it was used in an ongoing study of a melanoma helper peptide vaccine plus novel adjuvant combinations. " 01/01/2017 - "We describe the implementation of an adaptive design for identifying an optimal treatment regimen, defined by low toxicity and high immune response, in an early-phase trial of a melanoma helper peptide vaccine plus novel adjuvant combinations. " 12/01/2003 - "Peptide vaccine trials for melanoma: preclinical background and clinical results."
4.	Breast Neoplasms (Breast Cancer) 06/01/2020 - "Prospective, randomized, single-blinded, multi-center phase II trial of two HER2 peptide vaccines, GP2 and AE37, in breast cancer patients to prevent recurrence." 12/01/2016 - "In silico designing breast cancer peptide vaccine for binding to MHC class I and II: A molecular docking study." 04/01/2012 - "A GP2 peptide vaccine is currently being evaluated in a phase II efficacy trial enrolling breast cancer patients. " 02/01/2010 - "A virosomal formulated Her-2/neu multi-peptide vaccine induces Her-2/neu-specific immune responses in patients with metastatic breast cancer: a phase I study." 04/15/2009 - "We have conducted clinical trials with the HER2/neu E75 peptide vaccine in breast cancer patients with varying levels of HER2/neu expression. "
5.	Human Influenza (Influenza) 08/01/1998 - "Efficacy of anti-influenza peptide vaccine in aged mice." 11/14/2023 - "Therefore, the development of a broad-spectrum peptide vaccine that can stimulate an optimal antibody response has emerged as an innovative approach to addressing the influenza threat. " 02/17/2021 - "Rationally designed protein subunit vaccines are being developed for a variety of viruses including influenza, RSV, SARS-CoV-2 and HIV. " 01/01/2021 - "Rationally designed protein subunit vaccines are being developed for a variety of viruses including influenza, RSV, SARS-CoV-2, and HIV. " 01/01/2020 - "FLU-v, developed by PepTcell (SEEK), is a peptide vaccine aiming to provide a broadly protective cellular immune response against influenza A and B. "

Related Drugs and Biologics

1.	Peptides (Polypeptides)
2.	Vaccines
3.	Epitopes
4.	Antigens
5.	T-Lymphocyte Epitopes (Epitopes, T Lymphocyte)
6.	Proteins (Proteins, Gene)
7.	Biomarkers (Surrogate Marker)
8.	B-Lymphocyte Epitopes (B-Cell Epitope)
9.	Immune Checkpoint Inhibitors
10.	Oligodeoxyribonucleotides

Related Therapies and Procedures

1.	Immunotherapy
2.	Therapeutics
3.	Drug Therapy (Chemotherapy)
4.	Radiotherapy
5.	Intramuscular Injections