Glycated Serum Proteins

Proteins in serum that have undergone, in vivo, non-enzymatic modification with reducing sugars via the MAILLARD REACTION. They are analyzed to measure control of HYPERGLYCEMIA.

Also Known As:

Blood Protein, Glycated; Blood Protein, Glycosylated; Blood Proteins, Glycated; Blood Proteins, Glycosylated; Protein, Glycated Blood; Protein, Glycosylated Blood; Proteins, Glycated Blood; Proteins, Glycosylated Blood; Proteins, Glycosylated Serum; Serum Proteins, Glycated; Serum Proteins, Glycosylated; Glycated Blood Protein; Glycated Blood Proteins; Glycated Serum Protein; Glycosylated Blood Protein; Glycosylated Blood Proteins; Glycosylated Serum Protein; Glycosylated Serum Proteins; Serum Protein, Glycated; Serum Protein, Glycosylated

Networked: 88 relevant articles (6 outcomes, 5 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	He, Rongqiao: 2 articles (01/2022 - 01/2019)
2.	He, Tao: 2 articles (01/2022 - 01/2019)
3.	Wei, Yan: 2 articles (01/2022 - 01/2019)
4.	Xu, Yong: 2 articles (01/2022 - 01/2019)
5.	Du, Huan: 2 articles (06/2021 - 01/2020)
6.	Fan, Gang: 2 articles (06/2021 - 01/2020)
7.	Kuang, Tingting: 2 articles (06/2021 - 01/2020)
8.	Li, Qi: 2 articles (06/2021 - 01/2020)
9.	Xu, Tong: 2 articles (06/2021 - 01/2020)
10.	Xu, Xinmei: 2 articles (06/2021 - 01/2020)

Related Diseases

1.	Insulin Resistance 06/01/2014 - "Compared with non-ED group, WME-NS group had higher prevalence of early ED risk factors including endothelial dysfunction, insulin resistance, high level of glycosylated serum protein and abnormal NPTR. " 12/01/2018 - "Compared with the placebo group, the fasting and 2-h postprandial plasma glucose levels, glycosylated serum protein, and insulin resistance index of the MPCIR group are significantly decreased by 0.96 mmol L-1 , 1.47 mmol L-1 , 16.33 μmol L-1 , and 0.65 respectively (p < 0.001). " 06/01/2023 - "After 24 weeks of NOB intervention, the level of fasting blood glucose (FBG), glucose tolerance, insulin resistance, and glycosylated serum protein (GSP) are measured. " 01/01/2023 - "We measured a total of 17 OPEs in the blood, 11 OPE metabolites in urine, and 4 glycometabolic markers (fasting plasma glucose, glycated serum protein, fasting insulin, and homeostatic model assessment for insulin resistance). " 06/12/2021 - "Fasting blood glucose (FBG), glycosylated serum protein (GSP), insulin resistance index (HOMA-IR), insulin sensitivity index (ISI), lipopolysaccharide (LPS), and three inflammatory factors (TNF-α, IL-1 β and IL-6) were measured to evaluate the anti-diabetic activity of BK. "
2.	Metabolic Bone Diseases (Osteopenia) 05/01/2023 - "This study demonstrated that metformin significantly attenuated osteopenia, decreased serum glucose and glycated serum protein (GSP) levels, improved bone microarchitecture, and biomechanical properties in GK rats with T2DM. "
3.	Hyperglycemia 09/23/2023 - "Relevant parameters of routine blood and biochemical test, glycated serum protein (GSP), and history of hypertension and hyperglycemia were collected. " 03/15/2017 - "Fructosamine is a glycated serum protein that serves as an index of glycemic control in cats and is useful because it is not affected by stress hyperglycemia. " 01/01/2015 - "deterrimus extract displayed several improved biochemical parameters in the circulation: reduced hyperglycemia, lower triglyceride concentration and reduced glycated hemoglobin, glycated serum protein, and advanced glycation end product (AGE) levels. " 09/16/2023 - "Further evaluation of ANF in a T2DM ICR mouse model demonstrated its significant potential in alleviating hyperglycemia, reducing glycosylated serum protein levels, improving glucose tolerance and modulating total cholesterol and low-density lipoprotein levels, as well as antioxidant indices at a dosage of 0.04 g kg-1 . "
4.	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 12/01/1989 - "A comparison of direct measures of glycaemia and glycated blood proteins in insulin-dependent diabetes mellitus." 11/01/1989 - "Serial changes in glycosylated blood proteins and direct measures of glycemia were studied in 100 subjects with insulin-dependent diabetes mellitus (IDDM) over a 6-wk period while attempts were made to improve glycemic control. " 11/01/1989 - "An analysis of glycosylated blood proteins and blood glucose profiles over one year in patients with type 1 diabetes." 08/01/1981 - "The correlation between glycosylated serum protein and fasting serum glucose was closer in Type 2 than in Type 1 diabetes. " 11/01/1984 - "This study compares the utility of nonenzymatically glycosylated serum proteins (lys-GSP) to glycosylated hemoglobins (HbA1a-c) as control indices of glucose homeostasis in patients with IDDM. "
5.	Gestational Diabetes (Gestational Diabetes Mellitus) 09/01/1986 - "Glycosylated serum protein assay is not useful in detecting mild metabolic aberrations associated with gestational diabetes." 09/01/1986 - "Glycosylated serum protein level as a screening and diagnostic test for gestational diabetes mellitus." 03/01/1986 - "Glycosylated blood proteins were elevated in early gestation in women who developed gestational diabetes and may have predictive value in identifying women who will develop diabetes in pregnancy." 03/01/1986 - "Longitudinal assessment of glycosylated blood protein concentrations in normal pregnancy and gestational diabetes." 10/01/1984 - "However, there was such an overlap between these groups that individuals could not be categorized as normal or as having gestational diabetes mellitus on the basis of the glycosylated serum protein level. "

Related Drugs and Biologics

1.	Glucose (Dextrose)
2.	Blood Glucose (Blood Sugar)
3.	Glycated Hemoglobin (Glycosylated Hemoglobin)
4.	Lipids
5.	Insulin (Novolin)
6.	Pyruvic Acid (Pyruvate)
7.	Sucrose (Saccharose)
8.	Streptozocin (Streptozotocin)
9.	Prostaglandins
10.	Oxidoreductases (Dehydrogenase)

Related Therapies and Procedures

1.	Oral Administration
2.	Glycemic Control
3.	Renal Dialysis (Hemodialysis)