Sevoflurane (Ultane)

A non-explosive inhalation anesthetic used in the induction and maintenance of general anesthesia. It does not cause respiratory irritation and may also prevent PLATELET AGGREGATION.

Also Known As:

Networked: 3318 relevant articles (276 outcomes, 706 trials/studies)

Relationship Network

Drug Context: Research Results

Experts

1.	Xie, Zhongcong: 18 articles (01/2022 - 05/2009)
2.	Stowe, David F: 16 articles (04/2008 - 01/2002)
3.	Yan, Min: 15 articles (11/2021 - 02/2008)
4.	Riess, Matthias L: 15 articles (09/2018 - 07/2002)
5.	Zhang, Lei: 14 articles (10/2022 - 03/2014)
6.	Dong, Yuanlin: 14 articles (12/2021 - 05/2009)
7.	Zhao, Ping: 13 articles (08/2022 - 06/2015)
8.	Ma, Daqing: 13 articles (01/2022 - 11/2008)
9.	Yu, Yonghao: 13 articles (01/2022 - 03/2014)
10.	Zhang, Yiying: 13 articles (12/2021 - 06/2010)

Related Diseases

1.	Reperfusion Injury 01/01/2021 - "Diabetes impairs the protective effects of sevoflurane postconditioning in the myocardium subjected to ischemia/ reperfusion injury in rats: important role of Drp1." 07/01/2020 - "Protective effects and underlying mechanism of sevoflurane pretreatment on cerebral isch¬emia-reperfusion injury in mice." 04/01/2019 - "Sevoflurane exerts protective effects on liver ischemia/reperfusion injury by regulating NFKB3 expression via miR-9-5p." 10/20/2017 - "Sevoflurane preconditioning (SF-PreCon) has shown guaranteed protective effects in myocardial or cerebral ischemic/reperfusion injury. " 06/01/2016 - "Protective effects of sevoflurane in hepatic ischemia-reperfusion injury."
2.	Emergence Delirium 10/01/2020 - "The comparative efficacy of ancillary drugs on sevoflurane-related emergence agitation (EA) in paediatric anaesthesia for adenotonsillectomy remains unclear. " 10/01/2020 - "Comparative efficacy of ancillary drugs in sevoflurane-related emergence agitation after paediatric adenotonsillectomy: A Bayesian network meta-analysis." 01/01/2019 - "The comparative efficacy of ancillary drugs on sevoflurane related emergence agitation (EA) in children undergoing ophthalmic surgery remains controversial. " 08/01/2018 - "The aim of the study was to investigate the effects of visual preconditioning (application of an eyepatch over the eye to be operated for ≥3 h the day before surgery) on emergence delirium after ophthalmic surgery under sevoflurane anaesthesia. " 04/01/2011 - "Several studies have reported that sevoflurane was associated with a relatively high incidence of emergence agitation in children even in the absence of any surgical intervention. "
3.	Cognitive Dysfunction 01/01/2020 - "This study aimed to investigate the protective effects and underlying mechanisms of cistanche on sevoflurane-induced aged cognitive dysfunction rat model. " 04/01/2022 - "In this study, rats exposed to sevoflurane displayed cognitive dysfunction without changes in spontaneous activity; however, the sevoflurane-induced POCD could be relieved by Nec-1 pretreatment. " 01/01/2022 - "In this study, we found that IVX improved the cognitive dysfunction induced by sevoflurane in rats. " 11/18/2023 - "Our findings demonstrate that DHF effectively ameliorates sevoflurane-induced cognitive impairment in developing mice by restoring the balance between tau O-GlcNAcylation and phosphorylation. " 09/28/2023 - "Importantly, Tbx2 knockdown improved sevoflurane-induced cognitive disorder in aged rats, as evidenced by the increases in behavioral indexes. "
4.	Ischemia 07/01/2009 - "Rats anesthetized with sevoflurane during ischemia showed a significantly better outcome. " 08/01/2007 - "Sevoflurane postconditioning is as effective as preconditioning in protecting myocardial function after global ischemia. " 08/01/2020 - "However, it is unclear as to whether it participates in the protective effects of sevoflurane preconditioning in cardiomyocyte injury caused by oxidative stress in ischemia. " 01/01/2017 - "Caloric reduction restored myocardial dysfunction and the protective effect of sevoflurane against ischemia compared to WD-fed rats, whereas the protective effects of WD-feeding persisted. " 04/21/2009 - "To investigate the protective effects of postconditioning with different concentrations of sevoflurane on renal ischemia-reperfusion (I/R) injury. "
5.	Infarction (Infarctions) 09/01/2011 - "Sevoflurane postconditioning markedly improved left ventricular function and decreased LDH, infarct size in the male I/R+SPC group (P < 0.05 versus male I/R group) but not in the female I/R+SPC group. " 12/01/2010 - "Sevoflurane postconditioning significantly improved functional cardiac recovery and decreased infarct size in isolated rat hearts. " 01/01/2013 - "Sevoflurane or DZX reduced the infarct volume and improved neurological outcome in non-diabetic rats but not in diabetic rats, and the protective effects of sevoflurane in non-diabetic rats were inhibited by pretreatment with 5-HD. " 02/01/2015 - "Sevoflurane preconditioning improved neurological score and reduced infarct size at 24 h of reperfusion. " 07/01/2014 - "Sevoflurane preconditioning reduced infarct volume and improved neurological outcome in rats subjected to MCAO. "

Related Drugs and Biologics

1.	Propofol (Diprivan)
2.	Anesthetics (Anesthetic Agents)
3.	Dexmedetomidine
4.	Remifentanil (Ultiva)
5.	Isoflurane
6.	Fentanyl (Sublimaze)
7.	Midazolam (Versed)
8.	Halothane (Fluothane)
9.	Desflurane (I 653)
10.	Ketamine

Related Therapies and Procedures

1.	Anesthesia
2.	General Anesthesia
3.	Premedication
4.	Resuscitation
5.	Intravenous Anesthesia