Pinealectomy

01/01/2014 - "There were obtained sufficient experimental evidence of the stimulating effect on the development of tumors (transplanted, spontaneous and induced by various carcinogenic agents), disorders of circadian function of the pineal gland (light-induced desynchronosis) caused by knockout or mutation of clock genes, pinealectomy, content in conditions of constant light or natural light regime of the North, as well as jetlag modeling in laboratory rodents. "
12/01/2001 - "The tumor is known to have an accelerated development after pinealectomy. "
11/03/2000 - "Pinealectomy enhances tumor growth and metastatic spread in experimental animals. "
08/01/2000 - "I. Pinealectomy corrects congenital hormonal dysfunctions and prolongs life of cancer-prone C3H/He mice."
05/01/1995 - "To determine if this effect was longer-lasting (because of the possible role of the pineal in bowel malignancy) the crypt cell proliferation rate was determined in rat small bowel and colon 6 months after pinealectomy, using a stathmokinetic technique. "

12/01/1986 - "Maternal pinealectomy eliminated the influence of prenatal photoperiod on testicular and body weights of male pups, suggesting that a product from the maternal pineal gland communicates daylength to the fetus. "
01/01/2022 - "Pinealectomy reduced the maximal time to exhaustion and body weight gain while diminished motor activity, food intake, O2 consumption, CO2 production, and energy expenditure during the Dark phase in the youngest rat group. "
07/07/2014 - "Male European hamsters, deprived of seasonal time cues by pinealectomy and maintenance in constant photoperiod, were selected when expressing a subjective summer or subjective winter state in their circannual cycle of body weight, temperature, and testicular size. "
01/01/1989 - "The influence of multiple photoperiods and pinealectomy on gonads, pelage and body weight in male meadow voles, Microtus pennsylvanicus."
01/01/1988 - "Pinealectomy completely prevented gonadal regression as well as reduction in body weight and white adipose tissue content of the gonadal and retroperitoneal fat deposits in male meadow voles transferred from long to short day lengths. "

12/01/1975 - "Pinealectomy, superior cervical ganglionectomy and nervi conarii transection were equally effective in reversing the effects of blinding and anosmia on LRH activity."
01/01/1982 - "Pinealectomy tended to reverse the effects of blinding and anosmia on pars distalis size and PRL cell size, apparent number and ultrastructure. "
01/01/1975 - "At sacrifice of the castrates, pituitary FSH and LH concentrations were not modified by pinealectomy, however they were elevated by anosmia or by the double sensory-deprivation. "
01/01/1975 - "Similarly, final levels of FSH and LH were further increased in castrates by blinding, anosmia or blinding plus anosmia, but these changes were not consistently modified by pinealectomy. "
01/01/1975 - "Blinding plus anosmia lowered both daytime and nocturnal FSH titers; the lowering of nocturnal levels was reversed by pinealectomy. "

11/01/2005 - "Our findings suggest that lordosis may develop in bipedal rats, but pinealectomy is required for the development of lordoscoliosis. "
11/01/2005 - "Cervicothoracic lordosis developed in bipedal rats with or without pinealectomy. "
12/01/2005 - "Pinealectomy in chickens consistently produces scoliosis with lordosis, vertebral rotations, and rib humps, which have anatomic characteristics similar to those of human idiopathic scoliosis. "
09/01/2001 - "Because there normally is evidence of lordosis in the thoracic spine of chickens, the rotational instability of the spine induced by pinealectomy may produce a scoliotic deformity as a secondary phenomenon. "
01/01/1991 - "The sexual receptivity expressed as lordosis quotient (LQ) in MSG-treated female rats (2.5 months old) was significantly lower than that of the normal female ones, and this poor sexual receptivity of MSG-treated females could be improved by pinealectomy at the age of six weeks. "

11/19/2022 - "CASE REPORT A 45-year-old man with a history of pineal germinoma treated with pinealectomy, chemotherapy, radiation therapy, and ventriculoperitoneal shunt placement at age 21 presented with chronic neck pain and headaches, which initially improved following his surgery and concurrent therapies, yet progressively worsened over the following years. "
10/01/1998 - "Since melatonin exerts multiple physiological functions, once a clinical concept of "melatonin deficiency syndrome" is established, melatonin replacement therapy could be investigated in patients who have a pineal germinoma or who have undergone a neurosurgical pinealectomy."
01/01/2006 - "The objectives of the investigation were to assess hypersomnia, which progressively appeared in a young patient after a pinealectomy, chemotherapy, and radiotherapy for a typical germinoma, as well as the potential benefit of melatonin administration in the absence of its endogenous secretion. "