Patched-2 Receptor
A patched receptor that may function redundantly with the PATCHED-1 RECEPTOR to modulate hedgehog signaling. It may also play a role in epidermal development and as a TUMOR SUPPRESSOR PROTEIN. Mutations in the patched-2 gene are associated with BASAL CELL NEVUS SYNDROME; CARCINOMA, BASAL CELL; and MEDULLOBLASTOMA.
Also Known As:
PTCH2 Protein; Patched Homolog-2; Patched Receptor-2; Patched-2 Protein; Patched 2 Protein; Patched 2 Receptor; Patched Homolog 2; Patched Receptor 2; Receptor, Patched-2
Networked: 3
relevant articles (0 outcomes,
0 trials/studies)
Bio-Agent Context: Research Results
Experts
1. | Bieber, Marcia:
1 article
(08/2011)
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2. | He, Biao:
1 article
(08/2011)
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3. | Jablons, David:
1 article
(08/2011)
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4. | Schmid, Seraina:
1 article
(08/2011)
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5. | Teng, Nelson N H:
1 article
(08/2011)
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6. | Zhang, Fang:
1 article
(08/2011)
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7. | Zhang, Mallory:
1 article
(08/2011)
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8. | Dolf, G:
1 article
(07/2008)
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9. | Drögemüller, C:
1 article
(07/2008)
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10. | Leeb, T:
1 article
(07/2008)
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Related Diseases
1. | T-Cell Leukemia (Leukemia, T Cell)
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2. | Ovarian Neoplasms (Ovarian Cancer)
08/01/2011
- " Using real-time polymerase chain reaction, we studied 16 primary grade 3 International Federation of Gynecology and Obstetrics stage III serous ovarian cancer samples for expression of the Wnt pathway gene AXIN2, fibroblast growth factor 9, and Hh pathway gene expressions of glioma-associated oncogene 1, glioma-associated oncogene 2, patched homolog 1, patched homolog 2, Indian Hedgehog (HH), sonic HH, and Smoothened, a G protein-coupled receptor protein. "
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3. | Neoplasms (Cancer)
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4. | Lymphoma (Lymphomas)
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5. | Glioma (Gliomas)
08/01/2011
- " Using real-time polymerase chain reaction, we studied 16 primary grade 3 International Federation of Gynecology and Obstetrics stage III serous ovarian cancer samples for expression of the Wnt pathway gene AXIN2, fibroblast growth factor 9, and Hh pathway gene expressions of glioma-associated oncogene 1, glioma-associated oncogene 2, patched homolog 1, patched homolog 2, Indian Hedgehog (HH), sonic HH, and Smoothened, a G protein-coupled receptor protein. "
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