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ZBB-006

an antineoplastic synthetic diterpenoid derivative

Networked: 1 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Terpenes: 1461
    - Diterpenes: 1470
      - ZBB-006: 1

Experts

1.	Fan, Qian-Qian: 1 article (08/2010)
2.	Ji, Hui: 1 article (08/2010)
3.	Ji, Wen-Hao: 1 article (08/2010)
4.	Wang, Qiu-Juan: 1 article (08/2010)
5.	Wu, Yu-Lin: 1 article (08/2010)
6.	Zeng, Bu-Bing: 1 article (08/2010)

Related Diseases

1.	Neoplasms (Cancer) 08/01/2010 - "ZBB-006 is a new synthetic diterpenoid derivative which exhibited significant anti-proliferation activity against various cancer cell lines in our previous study. " 08/01/2010 - "We found that oral administration of ZBB-006 effectively suppressed the growth of HepG2 xenograft tumor in nude mice without body weight decline as compared with the control group. "
2.	Hepatocellular Carcinoma (Hepatoma) 08/01/2010 - "Collectively, our data indicated that ZBB-006 exerted a strong antitumor effect on HepG2 cells by initiating the mitochondrial-dependent apoptosis, and it has potential to be explored as a new promising therapeutic agent against human hepatoma." 08/01/2010 - "Here, we investigated the antitumor effect of ZBB-006 and its potential mechanisms in the human hepatocellular carcinoma cell line HepG2, both in vitro and in vivo. " 08/01/2010 - "Apoptosis induction of ZBB-006, a novel synthetic diterpenoid, in the human hepatocellular carcinoma cell line HepG2 in vitro and in vivo."
3.	Body Weight (Weight, Body) 08/01/2010 - "We found that oral administration of ZBB-006 effectively suppressed the growth of HepG2 xenograft tumor in nude mice without body weight decline as compared with the control group. "

Related Drugs and Biologics

1.	Diterpenes

Related Therapies and Procedures

1.	Oral Administration