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NC 0604

an antineoplastic antibody isolated from Streptomyces verticillus; structure in first source

Also Known As:

NC-0604; NC0604

Networked: 1 relevant articles (1 outcomes, 0 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Carbohydrates: 22023
- Glycoconjugates: 1353
  - Glycopeptides: 1928
    - Bleomycin: 9833
      - NC 0604: 1
Amino Acids, Peptides, and Proteins: 1
- Peptides: 82426
  - Glycopeptides: 1928
    - Bleomycin: 9833
      - NC 0604: 1

Experts

1.	Chen, Caixia: 1 article (09/2010)
2.	Chen, Ruxian: 1 article (09/2010)
3.	He, Qiyang: 1 article (09/2010)
4.	Shi, Weiwei: 1 article (09/2010)
5.	Xu, Hongzhang: 1 article (09/2010)
6.	Zhang, Xiumin: 1 article (09/2010)

Related Diseases

1.	Neoplasms (Cancer) 09/01/2010 - "Taken together, the anti-tumor actions of NC0604 involve activation of the apoptotic pathway and it is valuable for further drug development." 09/01/2010 - "The results showed that the colony formation inhibition of NC0604 was 2-10 times higher than that of bleomycin to several tumor cell types. " 09/01/2010 - "In comparison to bleomycin, a better antitumor efficacy of NC0604 was observed in the BALB/c mice loading mouse hepatoma H22 tumors. "
2.	Hepatocellular Carcinoma (Hepatoma) 09/01/2010 - "Flow cytometry assay detected an increase of intracellular reactive oxygen species and arrest at G2/M phase in human hepatoma HepG2 cells after exposure to NC0604. " 09/01/2010 - "In comparison to bleomycin, a better antitumor efficacy of NC0604 was observed in the BALB/c mice loading mouse hepatoma H22 tumors. "

Related Drugs and Biologics

1.	Bleomycin (Blenoxane)
2.	Reactive Oxygen Species (Oxygen Radicals)