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2',3',4',5'- tetrahydroxystilbene- 2- O- beta- D- glucoside

structure in first source

Also Known As:

stilbene glucoside; tetrahydroxystilbene glucoside

Networked: 31 relevant articles (5 outcomes, 4 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Carbohydrates: 22023
- Glycosides: 2119
  - Glucosides: 639
    - 2',3',4',5'-tetrahydroxystilbene-2-O-beta-D-glucoside: 31
Organic Chemicals: 133
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Aromatic Hydrocarbons: 291
      - Benzene Derivatives: 17
        Benzylidene Compounds: 10
        Stilbenes: 657
        2',3',4',5'-tetrahydroxystilbene-2-O-beta-D-glucoside: 31

Experts

1.	Li, Lin: 5 articles (04/2021 - 10/2006)
2.	Zhang, Lan: 5 articles (04/2021 - 10/2006)
3.	Liu, Jie: 2 articles (01/2018 - 01/2013)
4.	Zhang, Feng: 2 articles (01/2018 - 01/2013)
5.	Luo, Hong-Bo: 2 articles (09/2016 - 12/2009)
6.	Shi, Xiang-Qun: 2 articles (09/2016 - 12/2009)
7.	Xing, Ying: 2 articles (01/2013 - 10/2006)
8.	Yang, Jie: 2 articles (07/2010 - 04/2010)
9.	Yang, Qi-Dong: 2 articles (07/2010 - 12/2009)
10.	Zeng, Jin: 2 articles (07/2010 - 04/2010)

Related Diseases

1.	Cognitive Dysfunction 01/01/2018 - "This study intends to investigate the impact of tetrahydroxystilbene glucoside remedy for cognitive disorder and oxidative stress in Aβ1-42-induced AD mice and to clarify the mechanisms of action through Keap1/Nrf2 pathway. " 04/01/2021 - "Tetrahydroxy Stilbene Glucoside Ameliorates Cognitive Impairments and Pathology in APP/PS1 Transgenic Mice." 12/01/2009 - "The present study aims to evaluate the effects of tetrahydroxy stilbene glucoside (TSG), the extract from herbal medicine Polygoni Multiflori, on cognitive impairment and the over-expression of hippocampal amyloid precursor protein (APP) induced by chronic exposure to Al in rats. " 12/01/2009 - "Tetrahydroxy stilbene glucoside reduces the cognitive impairment and overexpression of amyloid precursor protein induced by aluminum exposure."
2.	Neoplasms (Cancer) 03/01/2015 - "Therefore, the aim of this study was to investigate whether antioxidants-resveratrol (RSVL), tetrahydroxystilbene glucoside (THSG), curcumin, and the ethanolic extract of Antrodia cinnamomea (EEAC)-have the ability to reduce Dox-induced ROS and have a synergistic anticancer effect with Dox that could prevent those side effects and enhance the efficacy of cancer treatment. "
3.	Alzheimer Disease (Alzheimer's Disease) 09/01/2016 - "It also reversed parameters for synaptic interface structure of gray type I. These findings indicate that tetrahydroxy stilbene glucoside has protective effects on the brain, and has prospects for its clinical application to improve the learning and memory abilities and treat Alzheimer's disease." 09/01/2016 - "An APP695V7171 transgenic mouse model of Alzheimer's disease was used and treatment with tetrahydroxy-stilbene glucoside was administered intragastrically. " 10/16/2006 - "Learning-memory deficit with aging in APP transgenic mice of Alzheimer's disease and intervention by using tetrahydroxystilbene glucoside." 01/01/2013 - "Tetrahydroxystilbene glucoside antagonizes age-related α-synuclein overexpression in the hippocampus of APP transgenic mouse model of Alzheimer's disease."
4.	Diabetic Nephropathies (Diabetic Nephropathy) 12/15/2010 - "Tetrahydroxystilbene glucoside ameliorates diabetic nephropathy in rats: involvement of SIRT1 and TGF-β1 pathway."
5.	Neuroblastoma 06/25/2011 - "Tetrahydroxystilbene glucoside protects human neuroblastoma SH-SY5Y cells against MPP+-induced cytotoxicity." 04/01/2021 - "Tetrahydroxystilbene glucoside protects against sodium azide-induced mitochondrial dysfunction in human neuroblastoma cells." 12/11/2006 - "In this study, human neuroblastoma cells (IMR-32) was used as system model to evaluate the protective role of rhaponticin (3,3',5-trihydroxy-4'-methoxystilbene 3-O-d-glucoside) a stilbene glucoside extracted from rhubarb roots (Rhei rhizoma) and rhapontigenin, its aglycone metabolite, against amyloid beta (1-42)-dependent toxicity. "

Related Drugs and Biologics

1.	Antioxidants
2.	Resveratrol
3.	Curcumin
4.	Sirtuin 1
5.	Proteins (Proteins, Gene)
6.	Amyloid beta-Peptides
7.	Amyloid (Amyloid Fibrils)
8.	rhapontigenin
9.	rhapontin
10.	Sodium Azide