HOME PRODUCTS COMPANY CONTACT FAQ

Research Dictionary Pharma

Sign Up FREE or Login

vismione B

from Cratoxylum sumatranum; structure in first source

Networked: 4 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Aromatic Hydrocarbons: 291
      - Polycyclic Aromatic Hydrocarbons: 2020
        Anthracenes: 12
        vismione B: 4
Polycyclic Compounds: 6
- Polycyclic Aromatic Hydrocarbons: 2020
  - Anthracenes: 12
    - vismione B: 4

Experts

1.	Bozzi, Adriana: 1 article (12/2019)
2.	Chounda, Gwladys A M: 1 article (12/2019)
3.	Nangmo, Pamela K: 1 article (12/2019)
4.	Nkengfack, Augustin E: 1 article (12/2019)
5.	Sass, Gabriele: 1 article (12/2019)
6.	Sayed, Nazish: 1 article (12/2019)
7.	Stevens, David A: 1 article (12/2019)
8.	Tsamo, Armelle T: 1 article (12/2019)
9.	Wu, Joseph C: 1 article (12/2019)
10.	Koysomboon, Sorwaporn: 1 article (03/2009)

Related Diseases

1.	Neoplasms (Cancer) 03/30/2009 - "Formoxanthone C (3) was found to be the most active against the NCI-H187 cancer cell line, with an IC(50) of 0.22 microg/mL, while vismione B (7) had the highest activity against Plasmodium falciparum, with an IC(50) of 0.66 microg/mL." 03/01/2002 - "Six new xanthones, cratoxyarborenones A-F (1-6), were isolated from the leaves, twigs, and/or stem bark of Cratoxylum sumatranum along with the known compound, vismione B (9), as active constituents by bioassay-directed fractionation using the KB human cancer cell line cytotoxicity assay. "
2.	Chagas Disease (American Trypanosomiasis) 12/01/2019 - "Vismione B Interferes with Trypanosoma cruzi Infection of Vero Cells and Human Stem Cell-Derived Cardiomyocytes."
3.	Lung Neoplasms (Lung Cancer) 06/01/2003 - "Bioassay-guided fractionation of the methanolic extracts of Vismia baccifera, V. jefensis, and V. macrophylla against human breast, CNS, and lung cancer cell lines resulted in the isolation of a new compound, ferruginin C (1), and seven known compounds, ferruginins A (2) and B (3), vismin (4), harunganin (5), vismione B (6), deacetylvismione H (7), and deacetylvismione A (8), as active constituents. "
4.	Infections 12/01/2019 - "Furthermore, in hiPSC-CM cultures, infection and multiplication rates in the presence of vismione B (10 µM) were significantly lower than in BNZ (11.5 µM), without showing signs of cytotoxicity. " 12/01/2019 - "When drug was applied after infection, anti-Trypanosoma effects of vismione B [10 µM) were significantly stronger than effects of BNZ (23 µM). " 12/01/2019 - "Reduced infection rates and multiplication by the quinone vismione B was superior to the commonly used therapeutic benznidazole (BNZ). "

Related Drugs and Biologics

1.	Xanthones
2.	1- (5- Isoquinolinesulfonyl)- 2- Methylpiperazine (H 7)
3.	formoxanthone C
4.	ferruginin C
5.	L 644711 (B-3(+))
6.	benzonidazole (benznidazole)
7.	quinone (benzoquinone)