cororubicin

generates superoxide radicals in tumor cells; structure given in first source

Also Known As:

2,6-Epoxy-2H-naphthaceno(1,2-b)oxocin-14-carboxylic acid, 5-0(O-2,6-dideoxy-alpha-L-lyxo-hexopyranosyl-(1->4)-O-2,3,6-trideoxy-3-C-methyl-3-nitro-beta-L-ribo-hexopyranosyl-(1->4)-2,6-dideoxy-alpha-L-lyxo-hexopyranosyl)oxy-4-dimethylami

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Related Diseases

1.	Neoplasms (Cancer) 11/01/1994 - "Cororubicin generated superoxide radicals in tumor cells and showed cytotoxicity, which was reduced by addition of an antioxidative agent, dithiothreitol (DTT)." 11/01/1994 - "Cororubicin, a new anthracycline antibiotic generating active oxygen in tumor cells."

Related Drugs and Biologics

1.	Anthracyclines
2.	Reactive Oxygen Species (Oxygen Radicals)
3.	Superoxides (Superoxide)
4.	Dithiothreitol (Cleland's Reagent)
5.	Anti-Bacterial Agents (Antibiotics)

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