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benzo(a)pyrene 7,8-oxide
RN given refers to cpd without isomeric designation; structure given in first source
Also Known As:
benzo(a)pyrene 7,8-epoxide; benzo(a)pyrene 7,8-oxide, (+-)-isomer; benzo(a)pyrene 7,8-oxide, (6bR)-isomer; benzo(a)pyrene 7,8-oxide, (6bS)-isomer
Networked:
1
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Organic Chemicals: 133
Hydrocarbons: 1713
Cyclic Hydrocarbons: 97
Aromatic Hydrocarbons: 291
Polycyclic Aromatic Hydrocarbons: 2020
Pyrenes: 10
Benzopyrenes: 67
benzo(a)pyrene 7,8-oxide: 1
Polycyclic Compounds: 6
Polycyclic Aromatic Hydrocarbons: 2020
Pyrenes: 10
Benzopyrenes: 67
benzo(a)pyrene 7,8-oxide: 1
Related Diseases
1.
Neoplasms (Cancer)
11/01/1976 - "
Application of 7,8-epoxy-,8,9,10-tetrahydrobenzo[a]pyrene (0.30 mumol every 2 weeks), a compound related to the carcinogenic benzo[a]pyrene 7,8-oxide but with the double bond removed from the 9,10-position of the molecule, did not elicit any tumors.
"
11/01/1976 - "
At the low dose (0.15 mumol), the compound was equipotent to the parent hydrocarbon, benzo[a]pyrene, and considerably more potent than its metabolic precursor, benzo[a]pyrene 7,8-oxide, in eliciting tumors, as determined by both the onset of tumors and the total number of animals developing carcinomas.
"
2.
Carcinoma (Carcinomatosis)
11/01/1976 - "
At the low dose (0.15 mumol), the compound was equipotent to the parent hydrocarbon, benzo[a]pyrene, and considerably more potent than its metabolic precursor, benzo[a]pyrene 7,8-oxide, in eliciting tumors, as determined by both the onset of tumors and the total number of animals developing carcinomas.
"
Related Drugs and Biologics
1.
Hydrocarbons
2.
Benzo(a)pyrene
3.
pyrene