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IMET 98-69
Also Known As:
3-(di-(2-hydroxyethyl)amino)acetophenone (4,5-diphenyloxazol-2-yl)hydrazone; zimet 98-69; ethanone, 1-(3-(bis(2-hydroxyethyl)amino)phenyl)-, (4,5-diphenyl-2-oxazolyl)hydrazone
Networked:
3
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Heterocyclic Compounds: 198
1-Ring Heterocyclic Compounds
Azoles: 2138
Oxazoles: 89
IMET 98-69: 3
Related Diseases
1.
Encephalitis (Encephalitis, Rasmussen)
01/01/1977 - "
Out of a series of eleven related hetarylhydrazones four derivatives (ZIMET 124/73, ZIMET 38/74, ZIMET 44/69, and IMET 98/69), after subcutaneous administration (0.5 mmole/kg per injection), were found to possess significant antiviral activity against rapidly progressing and highly lethal Mengo virus encephalitis in mice.
"
01/01/1978 - "
3-[Bis-(2-hydroxyethyl)-amino]-acetophenone-[4.5-diphenyl-oxazolyl-(2)]-hydrazone (IMET 98/69) was found to afford maximum "rates of protection" in intraperitoneally (i.p.) or intranasally (i.n.) induced Mengo virus encephalitis in mice when administered once daily at doses of 1 mmole/kg (456.5 mg/kg) subcutaneously (s.c.) or 4 mmoles/kg (1 826 mg/kg) perorally (p.o.).
"
01/01/1978 - "
Effect of 3-[bis-(2-hydroxyethyl)-amino]-acetophenone-[4.5-diphenyl-oxazolyl-(2)]-hydrazone (IMET 98/69) on lethal mengo virus encephalitis.
"
2.
Infections
11/01/1979 - "
The potential in vivo antiviral activity of 3-[bis-(2-hydroxyethyl)-amino]-acetophenone-[4,5-diphenyl-oxazolyl-(2)]-hydrazone (IMET 98/69) was evaluated on model infections in mice.
"
Related Drugs and Biologics
1.
Hydrazones
2.
Antiviral Agents (Antivirals)
3.
acetophenone
4.
diphenyl (biphenyl)
5.
ZIMET 38-74