Tannic Acid

Also Known As:

(2S,3R,4S,5R,6R)-3,4,5-tris(3,4-dihydroxy-5-(3,4,5-trihydroxybenzoyloxy)benzoyloxy)-6-((3,4-dihydroxy-5-(3,4,5-trihydroxybenzoyloxy)benzoyloxy)methyl)oxan-2-yl 3,4-dihydroxy-5-(3,4,5-trihydroxybenzoyloxy)benzoate; Gallotannic Acid; Gallotannin

Networked: 618 relevant articles (54 outcomes, 99 trials/studies)

Relationship Network

Drug Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Aromatic Hydrocarbons: 291
      - Benzene Derivatives: 17
        Phenols: 677
        Polyphenols: 7483
        Tannic Acid: 618

Experts

1.	Abe, Tatsuya: 8 articles (01/2022 - 11/2007)
2.	Hachiro, Yoshikazu: 8 articles (01/2022 - 11/2007)
3.	Kunimoto, Masao: 8 articles (01/2022 - 11/2007)
4.	Kim, Sung-Hoon: 8 articles (01/2018 - 05/2009)
5.	Chowdhury, Pallabita: 6 articles (03/2020 - 03/2018)
6.	Hatami, Elham: 6 articles (03/2020 - 03/2018)
7.	Yallapu, Murali M: 6 articles (03/2020 - 03/2018)
8.	Hwang, Dae Youn: 5 articles (01/2021 - 01/2016)
9.	Kim, Ji Eun: 5 articles (01/2021 - 01/2016)
10.	Chu, Li: 5 articles (12/2020 - 09/2017)

Related Diseases

1.	Neoplasms (Cancer) 03/09/2021 - "To overcome such obstacles, novel drug delivery systems have been employed to deliver tannic acid with the aim of improving its applications and/or efficacy against cancer cells. " 06/01/2022 - "Herein, we report a facile strategy to construct a tumor-triggered tannic acid (TA) nanoassembly with improved drug delivery efficiency. " 04/03/2013 - "The present study evaluated cytotoxic, antitumor, and tumor progression activities of a gallotannin-rich fraction derived from Caesalpinia spinosa (P2Et). " 08/01/2003 - "The aim of this study was to assess the anti-CXCL12/CXCR4 activity of a commercial tannic acid and evaluate its potential to inhibit tumor cell migration and angiogenesis in vitro. " 08/01/2023 - "Therefore, the use of plant compounds such as tannic acid with UPR-inducing properties can be proposed as a possible treatment method for cancer. "
2.	Inflammation (Inflammations) 01/01/2023 - "Tannic acid, an IL-1β-direct binding compound, ameliorates IL-1β-induced inflammation and cartilage degradation by hindering IL-1β-IL-1R1 interaction." 01/01/2023 - "This study indicated that tannic acid mitigated anxiety-related behaviors through decreasing inflammation and oxidative stress and positively modifying IL-1β/GABAA receptor pathway. " 01/01/2018 - "In this study, we investigated how tannic acid (TA) protects the skin from inflammation caused by external irritation. " 12/01/2023 - "The findings showed that tannic acid had a protective effect on the changes in the oxidative stress and inflammation system in the rat spleen as a result of the application of tannic acid together with DOX." 10/01/2021 - "Tannic acid is a gastroprotective that regulates inflammation and oxidative stress."
3.	Carcinogenesis 01/01/2015 - "Tannic acid (TA) is reported to be effective against various types of chemical-induced toxicities and carcinogenesis as well. " 01/01/2012 - "Tannic acid (TA) is reported to be effective against various types of chemically induced toxicity and also carcinogenesis. " 11/01/1989 - "Our data suggest that dietary supplementation with tannic acid affords protection against BP-induced forestomach and lung tumorigenesis in rodents." 03/15/1989 - "Protection against chemically induced skin tumorigenesis in SENCAR mice by tannic acid." 03/15/1989 - "These results suggest that tannic acid may prove useful in reducing the risk of chemically-induced skin tumorigenesis."
4.	Wounds and Injuries (Trauma) 06/01/2023 - "Additionally, if clinical trials confirm its effectiveness, tannic acid may be useful in healing wounds for patients undergoing septorhinoplasty." 03/08/2022 - "Moreover, recent progress in the application of tannic acid composites is also summarized, including bone regeneration, skin adhesives, wound dressings, drug loading and photothermal conversion. " 10/01/2020 - "The results showed that higher content of tannic acid increases the surface free energy and roughness, which is beneficial when considering the application of the materials as wound dressings. " 10/01/2020 - "The mechanical properties and bactericidal degradation effectiveness of tannic acid-based thin films for wound care." 01/01/2009 - "During World War II, however, tannic acid treatment was linked to liver damage due to absorption from the wound. "
5.	Infections 01/01/2022 - "Having uncovered in our previous study that transcriptional regulation of the CpHsp24 gene in response to tannic acid supplementation and CHV1 infection was similar to that of the lac3, and that conserved phenotypic changes of reduced virulence were observed in mutants of both genes, we inferred that both genes were implicated in a common pathway. " 01/31/2018 - "In this study, we investigated the in vitro and in vivo effects of tannic acid (TA) against Brucella abortus infection. " 05/04/2023 - "perfringens infection and determining the appropriate dosage of tannic acid with regard to NE. " 01/01/2022 - "Laccase3 gene (lac3) transcription is induced by tannic acid, a group of phenolic compounds found in chestnut trees, and its induction is regulated by the hypovirus CHV1 infection. " 12/01/2019 - "This preparation method overcomes the limitation of the traditional hydrophilic tannic acid as a coating and provides a new method for preventing medical indwelling device-associated infections."

Related Drugs and Biologics

1.	Hydrogels
2.	Polyphenols
3.	Resveratrol
4.	aluminum sulfate (alum)
5.	Doxorubicin (Adriamycin)
6.	Tannins
7.	Proteins (Proteins, Gene)
8.	Creatinine
9.	Astringents
10.	Gallic Acid

Related Therapies and Procedures

1.	Drug Therapy (Chemotherapy)
2.	Controlled Hypotension
3.	Sclerotherapy
4.	Ligation
5.	Punctures