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bromelain and acetylcysteine drug combination

Also Known As:

BromAc; bromelain and N-acetylcysteine drug combination; bromelain and acetylcysteine; bromelain, acetylcysteine drug combination

Networked: 10 relevant articles (1 outcomes, 0 trials/studies)

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Bio-Agent Context: Research Results

Experts

1.	Morris, David L: 6 articles (01/2022 - 01/2021)
2.	Valle, Sarah J: 5 articles (01/2022 - 01/2021)
3.	Akhter, Javed: 4 articles (01/2022 - 01/2021)
4.	Badar, Samina: 4 articles (01/2022 - 01/2021)
5.	Ke, Kevin: 4 articles (01/2022 - 01/2021)
6.	Pillai, Krishna: 4 articles (01/2022 - 01/2021)
7.	Mekkawy, Ahmed H: 3 articles (01/2022 - 01/2021)
8.	Albuquerque, George Rego: 1 article (01/2022)
9.	Carlos, Renata Santiago Alberto: 1 article (01/2022)
10.	Carter, Carly J: 1 article (01/2022)

Related Diseases

1.	Sarcoma (Soft Tissue Sarcoma) 01/01/2022 - "A novel method for potentiation of chemotherapy in soft tissue sarcomas with BromAc." 01/01/2022 - "Here, we investigated the efficacy of BromAc in combination with doxorubicin for four subtypes of sarcoma. "
2.	Pseudomyxoma Peritonei 10/01/2023 - "Effective Use of Bromelain and Acetylcysteine (BromAc®) for Treatment of Perigastric Pseudomyxoma Peritonei: A Case Report." 08/16/2021 - "Intraperitoneal administration of BromAc (bromelain + acetylcysteine) is currently undergoing a phase 1 clinical trial for pseudomyxoma peritonei at our institution. " 01/01/2021 - "Novel Use of Bromelain and Acetylcysteine (BromAc®) for Pleural Involvement in Pseudomyxoma Peritonei." 06/24/2023 - "A combination of bromelain and acetylcysteine, BromAc®, is an efficient intraperitoneal mucolytic for thick mucus secreted in pseudomyxoma peritonei (PMP). " 06/29/2023 - "Oral administration of bromelain and acetylcysteine in pseudomyxoma peritonei (PMP) caused by low-grade appendiceal mucinous neoplasm (LAMN): a case report."
3.	Neoplasms (Cancer) 01/01/2021 - "Addition of bromelain and acetylcysteine to gemcitabine potentiates tumor inhibition in vivo in human colon cancer cell line LS174T." 01/01/2022 - "BromAc is a novel drug combination developed as a mucolytic agent which has demonstrated anticancer activity both in vitro and in vivo in several cancers. " 01/01/2021 - "The combinations of Bromelain and Acetylcysteine (BromAc®) with cytotoxics such as Gemcitabine, 5-Fluorouracil or Oxaliplatin have shown a dramatic reduction in IC50 values in a variety of cancers, including colon cancer, suggesting the possibility of effective treatment without undesired side effects. "
4.	Neoplasms, Cystic, Mucinous, and Serous 06/29/2023 - "Here we report the first case of PMP with peritoneal dissemination of mucinous implants caused by low-grade appendiceal mucinous neoplasm (LAMN) in a 58-year-old white male exclusively treated by appendectomy and oral administration of bromelain and acetylcysteine in the context of a medical self-experimentation (by co-author T.R.). " 06/29/2023 - "Oral administration of bromelain and acetylcysteine in pseudomyxoma peritonei (PMP) caused by low-grade appendiceal mucinous neoplasm (LAMN): a case report."
5.	Respiratory Tract Diseases (Respiratory Tract Disease) 04/14/2023 - "Effect of Nebulized BromAc on Rheology of Artificial Sputum: Relevance to Muco-Obstructive Respiratory Diseases."

Related Drugs and Biologics

1.	Doxorubicin (Adriamycin)
2.	Expectorants (Mucolytics)
3.	Gemcitabine
4.	Fluorouracil (Carac)
5.	Drug Combinations
6.	Oxaliplatin (Eloxatin)

Related Therapies and Procedures

1.	Intraperitoneal Injections
2.	Drug Therapy (Chemotherapy)
3.	Appendectomy
4.	Oral Administration