diaporine

10/01/2016 - "Collectively, our results suggest that diaporine can act as an anti-cancer agent and this function is dependent on promoting high level ROS release of cancer cells."
10/01/2016 - "Further investigation show that diaporine can efficiently induce an intensive breast cancer cell cycle arrest especially in G2 phase and finally leads to cancer cell apoptosis by flow cytometer analysis. "
10/01/2016 - "Firstly, we evaluate the sensitivities of diaporine in several cancer cells and the results show that diaporine has proliferation-inhibitory effect against cancer cells via MTT assay, especially on breast cancer cells. "
10/01/2016 - "Diaporine is a novel fungal metabolic product and has an unprecedented symmetric polyketide with a novel framework from diaporthe sp. In the current study, we researched the anti-cancer role of this natural compound. "
08/16/2022 - "The combination of these drugs at low concentration for 48 h in vitro noticeably showed that diaporine improved the inhibitory effect on the number of cancer cells induced by oxaliplatin or doxorubicin. "

08/16/2022 - "In this study, three human hepatocarcinoma cell lines (HepG2, Hep3B, and Huh7) were used to evaluate the efficacy of diaporine alone and in combination with the standard cytotoxic drugs oxaliplatin and doxorubicin for the treatment of liver cancer. "
08/16/2022 - "Based on these findings, we suggest that diaporine in combination with the standard cytotoxic drugs oxaliplatin and doxorubicin may play a role in the treatment of liver cancer."
08/16/2022 - "Diaporine Potentiates the Anticancer Effects of Oxaliplatin and Doxorubicin on Liver Cancer Cells."

08/16/2022 - "Decreases in cell numbers after 48 h treatment with diaporine, oxaliplatin, and doxorubicin were also demonstrated in two additional hepatoma cell lines, Hep3B and Huh7. "

10/01/2016 - "For the mechanism by which mediated the breast cancer cell death, we find that diaporine can induce an increase of ROS level in breast cancer cells. "
10/01/2016 - "In addition, we find that diaporine can disrupt the morphology and viability of breast cancer cells and their migration and invasion capacities are also impaired tested by using wound healing method and transwell. "
10/01/2016 - "A novel small molecule compound diaporine inhibits breast cancer cell proliferation via promoting ROS generation."
10/01/2016 - "Further investigation show that diaporine can efficiently induce an intensive breast cancer cell cycle arrest especially in G2 phase and finally leads to cancer cell apoptosis by flow cytometer analysis. "
10/01/2016 - "Firstly, we evaluate the sensitivities of diaporine in several cancer cells and the results show that diaporine has proliferation-inhibitory effect against cancer cells via MTT assay, especially on breast cancer cells. "