Nickel

01/01/2023 - "However, all patients with suspected nickel allergy showed a significant clinical and functional improvement with excellent short-term survival rates. "
03/01/2011 - "The EU Nickel Directive revisited--future steps towards better protection against nickel allergy."
02/21/2022 - "Many nanomaterials have been developed to reduce skin allergies by capturing nickel, but few agents are effective and safe. "
01/01/2023 - "In this cohort of revised TKA patients with suspected nickel allergy based on clinical presentation and LTT positive results, intraoperative histopathology was essentially normal. "
09/01/2018 - "Patch test (PT) is the gold standard to reveal nickel (Ni) allergy. "

06/01/1988 - "The clearance of the nickel from the lungs was very slow and the biological half time was determined 7.7 mo. Although the rats were exposed continuously to NiO(G) for 12 mo and kept for 8 mo clearance period, there were no malignant tumors in any of the exposed animals."
08/01/1981 - "Clinical investigations have resulted in improved diagnosis, classification, and management of cancers of respiratory organs in nickel refinery workers. "
06/30/2022 - "However, few studies have been devoted to analyzing the effects of nickel at environmental concentrations in cancer patients. "
01/01/2020 - "Our evaluation of the epidemiology studies indicates that there is no substantive evidence of increased respiratory cancer risk in workers exposed predominantly to metallic nickel. "
11/01/2017 - "Average lifetime cancer risks for the lead in Ardakan and nickel in Meibod and Bahabad were shown to be 1.09 × 10-3, 1.67 × 10-1, and 2 × 10-1, respectively, demonstrating high carcinogenic risk compared to similar standards and studies. "

11/01/2011 - "Efficacy of oral hyposensitization in allergic contact dermatitis caused by nickel."
11/01/2018 - "Short contact with nickel causes allergic contact dermatitis: an experimental study."
07/01/2014 - "The aim of this study based on the records of the dermatology department of a tertiary referral hospital was to describe patients treated for allergic contact dermatitis induced by nickel between 2000 and 2010. "
07/01/2014 - "Allergic contact dermatitis due to nickel: descriptive study in a tertiary hospital, 2000-2010."
01/01/2012 - "This study confirms that nickel levels on the skin in coin handling occupations and some others are sufficient to induce an allergic contact dermatitis in some nickel-allergic subjects. "

03/01/1980 - "In 9 out of 17 patients suffering from dermatitis, a diet with a low nickel content has improved their condition. "
02/01/1978 - "The dermatitis of 9 of the 17 patients improved during a period of 6 weeks on a low nickel diet. "
01/01/2021 - "Women are reported to have higher rates of nickel sensitization than men, but there have been few studies of sex-related differences in dermatitis associated with occupational nickel exposure. "
02/01/2019 - "Combined with the allergic responses resulting from the same exposures reported previously, this study highlights that short skin exposure to nickel-releasing items may cause allergic nickel dermatitis."
11/01/2018 - "This experimental study showed that relatively short repeated skin contact (3 × 10 min) with metallic nickel elicits allergic nickel dermatitis in irritated skin and at sites with previous dermatitis. "

01/01/1984 - "The discovery that the carcinogenic activities of particulate nickel compounds are correlated with a physical property, namely the nickel mass-fraction, may help to elucidate the mechanisms of nickel carcinogenesis; the observation that nickel stimulation of erythropoiesis is correlated with carcinogenic activity provides a new in vivo screening test for use in determining the carcinogenic risk of nickel compounds."
01/01/2017 - "Our studies provide a significant insight into understanding the alteration and role of MEG3 in nickel-induced lung tumorigenesis."
01/01/2016 - "Although the mechanisms of nickel-induced carcinogenesis are not well understood, recent studies suggest that stem cells/cancer stem cells are likely important targets. "
05/01/2013 - "Our study elucidated a novel molecular mechanism of nickel-induced tumorigenesis."
05/01/2013 - "In the past few years, researchers did a large number of studies about the molecular mechanisms of nickel carcinogenesis, and they focused on activation of proto-oncogenes and inactivation of anti-oncogenes caused by gene point mutation, gene deletion, gene amplification, DNA methylation, chromosome condensation, and so on that were induced by nickel. "