Hemoglobins (Hemoglobin)

The oxygen-carrying proteins of ERYTHROCYTES. They are found in all vertebrates and some invertebrates. The number of globin subunits in the hemoglobin quaternary structure differs between species. Structures range from monomeric to a variety of multimeric arrangements.

Also Known As:

Networked: 38348 relevant articles (1342 outcomes, 3599 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Gladwin, Mark T: 69 articles (11/2022 - 12/2002)
2.	Lang, Florian: 67 articles (01/2018 - 07/2009)
3.	Fucharoen, Supan: 45 articles (07/2023 - 01/2002)
4.	Buehler, Paul W: 42 articles (01/2024 - 10/2005)
5.	Sakai, Hiromi: 40 articles (01/2024 - 07/2002)
6.	Fucharoen, Goonnapa: 39 articles (11/2022 - 01/2002)
7.	Schaer, Dominik J: 38 articles (11/2023 - 07/2002)
8.	Zhang, Wei: 35 articles (03/2024 - 09/2003)
9.	Wang, Wei: 35 articles (01/2023 - 01/2009)
10.	Palmer, Andre F: 34 articles (01/2024 - 11/2008)

Related Diseases

1.	Anemia 05/01/2016 - "Thereafter, his hemoglobin levels increased, and his anemia dramatically improved after 3 months." 07/01/1980 - "Anemia is the abnormality most likely to be encountered, and investigation of a marginal reduction in the hemoglobin level of an elderly patient may be rewarded with a specific diagnosis of a disease that can be effectively treated, at least for a time." 10/01/2013 - "To improve patients' outcomes, further study is required to more fully explore the risk of anemia, optimal hemoglobin level, and the risk and efficacy of RBC transfusion. " 01/01/2020 - "In parallel, JPYS markedly improved CKD anemia through upregulation of red blood cell (RBC), hemoglobin (HGB), and hematocrit (HCT). " 10/01/2016 - "The marked decrease in hemoglobin content in first-year females of both host species correlated with the highest parasite load and indicated a risk of anemia. "
2.	Neoplasms (Cancer) 03/10/2004 - "With the depth correction, more uniform absorption maps for target layers at different depths are obtained from the phantoms, and the correlation between the reconstructed hemoglobin concentration maps of deeply located, large cancers and the histological microvessel density counts are dramatically improved." 10/01/1986 - "A hemoglobin level of 12g/dl or more was associated with a significant improvement in complete local tumor regression at 6 months and durable local tumor control for patients with T3 cancer or a cancer of grade 3 histology. " 10/01/2013 - "On multivariate analysis, improved LRC was significantly associated with pre-RT hemoglobin levels≥12 g/dl (risk ratio [RR] 2.22; 95% confidence interval [CI] 1.19–4.13; p=0.013), tumor site (RR 1.39; 95% CI 1.14–1.70; p=0.001), lower T category (RR 1.67; 95% CI 1.18–2.44; p=0.003), and lower N category (RR 4.18; 95% CI 1.90–10.55; p<0.001). " 10/01/2011 - "Improved treatment outcomes were significantly associated with positive HPV status, better performance status, lower tumor stage, and pretreatment hemoglobin levels ≥ 12 g/dl. " 05/01/2002 - "An aggressive combination of immunoactive Nutraceuticals was effective in significantly increasing NK function, other immune parameters and hemoglobin from PBMC or plasma in patients with late stage cancers. "
3.	Body Weight (Weight, Body) 03/20/2024 - "In terms of clinical outcomes, the Higher SM group achieved a significant reduction in body weight (estimate: -6.06, SD 0.87 kg; P<.001) and hemoglobin A1c (estimate: -0.38, SD 0.11%; P=.02), whereas the Lower SM group exhibited no improvements. " 07/06/2021 - "Univariate analysis showed that decreased body weight (BW), decreased body mass index (BMI), decreased AST level, decreased hemoglobin A1c, and high m-CI were significantly related with improved ALT level. " 01/01/2021 - "Meanwhile, the mean body weight loss was 13 kg. There was a significant reduction of hemoglobin A1c (HbA1c) % by 0.43%. " 01/01/2020 - "The DTSQ score improved significantly and both hemoglobin A1c and body weight showed a significant decrease throughout treatment (all P < 0.0001). " 01/01/2014 - "There was a significant reduction in hemoglobin A1c (HbA1c, -0.2 ± 0.56% versus 0.08 ± 0.741%; P < 0.05) and body weight (-1.19 ± 1.39 kg versus -0.61 ± 2.04 kg; P < 0.05) in the intervention group as compared to the control group. "
4.	Hemorrhage 01/01/2023 - "In patients who present to the hospital with GI bleeding, CTA can be a helpful triage tool that is most helpful in older patients with suspected lower GI bleeding with a drop in hemoglobin from baseline. " 08/01/2010 - "Marked decrease in hemoglobin value was more frequent in patients with re-bleeding than those without (P = 0.07). " 08/01/2010 - "Marked decrease in hemoglobin value [OR; 18.8, 95% CI; 3.4-152.0] and earlier CE examination within a week after the last episode of bleeding [OR; 8.0, 95% CI; 2.2-35.9] were factors associated with positive CE findings. " 09/07/2023 - "The notable reduction in hemoglobin levels indicated significant bleeding, which was confirmed through contrast angiography and cured by arterial embolization. " 01/01/2023 - "We present its efficacy over the duration of 19 days of Impella 5.5 support where hemoglobin level remained stable, and platelet count significantly improved despite a brief episode of gastrointestinal bleeding. "
5.	Insulin Resistance 09/01/2011 - "After 2 years, remission was achieved in 13 of 20 patients (65%), and hemoglobin A1c decreased from 8.1 ± 1.8% to 5.9 ± 1.1% and homeostasis model assessment of insulin resistance from 5.7 ± 3.2 to 1.9 ± 0.8 after 12 months. " 01/01/2016 - "Insulin resistance homeostasis model assessment for insulin resistance was lowered throughout the study, with a 20% reduction in hemoglobin A1c levels (p<0.001) at week 12, despite reduced anti-diabetes treatment. " 01/01/1999 - "The findings of the current study suggest that hematocrit and hemoglobin values might be added to the clustering variables related to the insulin resistance syndrome in the SHR strain." 04/01/2024 - "Mexican PwS had higher hemoglobin A1c levels, insulin resistance, and body mass index than NHW PwS. " 03/15/2023 - "After logistic regression analysis adjusted for sex, age, hemoglobin A1c, body mass index, systolic blood pressure, estimated glomerular filtration rate, homeostasis model assessment of insulin resistance, AUCglucose and AUCglucagon, patients in quartile 4 of the AUCGLP-1 presented a lower risk of microalbuminuria compared with the patients in quartile 1 (odds ratio = 0.547, 95% confidence interval: 0.325-0.920, P = 0.01). "

Related Drugs and Biologics

1.	Iron
2.	Glucose (Dextrose)
3.	Oxygen (Dioxygen)
4.	Insulin (Novolin)
5.	Blood Glucose (Blood Sugar)
6.	Erythropoietin
7.	Albumins
8.	Ferritins (Ferritin)
9.	Creatinine
10.	Triglycerides (Triacylglycerol)

Related Therapies and Procedures

1.	Therapeutics
2.	Drug Therapy (Chemotherapy)
3.	Blood Transfusion (Blood Transfusions)
4.	Glycemic Control
5.	Length of Stay