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Etidocaine (Duranest)
A local anesthetic with rapid onset and long action, similar to BUPIVACAINE.
Also Known As:
Duranest
; 2-(Ethylpropylamino)-2',6'-butyroxylidide; W-19053; W 19053; W19053; Butanamide, N-(2,6-dimethylphenyl)-2-(ethylpropylamino)-, (+-)-
Networked:
59
relevant articles (
5
outcomes,
5
trials/studies)
Relationship Network
Drug Context: Research Results
Organic Chemicals: 133
Amines: 4871
Aniline Compounds: 46
Anilides: 22
Acetanilides: 7
Etidocaine: 59
Amides: 2428
Anilides: 22
Acetanilides: 7
Etidocaine: 59
Related Diseases
1.
Pain (Aches)
07/01/1990 - "
The time until complete recovery and the time until pain onset were found to be longer for the etidocaine surgeries.
"
04/01/1990 - "
Mean analog pain scores were significantly lower in the etidocaine group than the placebo group after return from the recovery room and the time of discharge (p0.05); there was no significant differences between the 2 groups 24 hours after discharge in terms of pain level.
"
01/01/1975 - "
Relief of pain following upper abdominal operations by thoracic epidural block with etidocaine.
"
01/01/1975 - "
Single-dose intercostal nerve blocks with etidocaine for pain relief after upper abdominal surgery.
"
11/01/1984 - "
Residual pain was noted in some of the subjects given etidocaine after complete resolution of sensory anesthesia.
"
2.
Hemorrhage
07/01/1990 - "
Surgeons' rating of surgical bleeding was significantly greater for the etidocaine procedures.
"
01/01/1992 - "
Etidocaine has less pronounced effects on the cardiovascular system, but its use may be associated with inadequate control of intraoperative bleeding.
"
01/01/1986 - "
Comparison of etidocaine and lidocaine for control of intra- and post-operative bleeding and pain.
"
01/01/1986 - "
Etidocaine hydrochloride, an amide-type of local anesthetic with prolonged duration of action, was evaluated and compared with the standard local anesthetic lidocaine to determine its efficacy of action and its effect on bleeding during and following the removal of impacted mandibular third molar teeth.
"
3.
Postoperative Pain
04/01/1990 - "
The results of a randomized, double-blind, clinical trial suggest that topical etidocaine can significantly reduce postoperative pain when applied to the fallopian tubes after tubal banding.
"
04/01/1990 - "
Intraoperative topical etidocaine for reducing postoperative pain after laparoscopic tubal ligation.
"
03/01/1986 - "
Topical etidocaine during laparoscopic tubal occlusion for postoperative pain relief.
"
08/01/1976 - "
Clinical evaluation of etidocaine in continuous caudal analgesia for pelvic floor repair and post-operative pain relief.
"
10/01/1976 - "
In a following open study with etidocaine 1% and mepivacaine 1% about 80% of the the patients in the etidocaine group never experienced any post-operative pain compared to about 50% in the mepivacaine group.
"
4.
Hypesthesia (Numbness)
10/01/1983 - "
Etidocaine proved 2.16 times longer acting than lidocaine with respect to recovery from lower lip numbness and 1.75 times longer acting than lidocaine with respect to the onset of postoperative pain.
"
07/01/1984 - "
adequate anesthesia was rapidly produced by both agents but the duration of action of etidocaine was longer than that of lidocaine as reflected in more prolonged numbness of the lip and delayed onset of pain.
"
03/01/1985 - "
Bupivacaine and etidocaine had a longer period of soft-tissue numbness, but a significantly shorter duration of tooth analgesia than lidocaine.
"
5.
Torsades de Pointes (Torsade de Pointes)
07/01/1986 - "
The results of this study suggest that bupivacaine, etidocaine, and occasionally mepivacaine can result in a Torsades de Pointes-like syndrome following intravenous administration.
"
07/01/1986 - "
Six of seven bupivacaine, six of seven etidocaine, two of eight mepivacaine, and none of eight lidocaine animals sustained a polymorphic, undulating ventricular tachycardia similar to Torsades de Pointes following burst ventricular pacing.
"
Related Drugs and Biologics
1.
Local Anesthetics
2.
Lidocaine (Xylocaine)
3.
Bupivacaine (Bupivacaine Hydrochloride)
4.
Flurbiprofen (Froben)
5.
Analgesics (Analgesic Drugs)
6.
Amides
7.
Anesthetics (Anesthetic Agents)
8.
Mepivacaine (Carbocaine)
9.
Oxycodone (Oxycontin)
10.
Acetaminophen (Paracetamol)
Related Therapies and Procedures
1.
Anesthesia
2.
Brachial Plexus Block
3.
Intravenous Administration
4.
Analgesia
5.
Injections