Immunomodulators that regulate immune system either in stimulatory or inhibitory fashion allowing IMMUNE TOLERANCE. Activation of suppressed immune system (IMMUNOSUPPRESSION (PHYSIOLOGY)) in immunotherapy by IMMUNE CHECKPOINT INHIBITORS often targets inhibitory checkpoint molecules.
Also Known As:
Checkpoint Molecule, Immune; Checkpoint Molecule, Inhibitory; Checkpoint Molecule, Stimulatory; Checkpoint Protein, Immune; Molecule, Immune Checkpoint; Protein, Immune Checkpoint; Immune Checkpoint Molecule; Immune Checkpoint Molecules; Immune Checkpoint Protein; Inhibitory Checkpoint Molecule; Inhibitory Checkpoint Molecules; Stimulatory Checkpoint Molecule; Stimulatory Checkpoint Molecules