Narcotic-Related Disorders

Disorders related to or resulting from abuse or misuse of NARCOTICS.

Also Known As:

Abuse, Narcotic; Abuses, Narcotic; Addiction, Narcotic; Dependence, Narcotic; Disorder, Narcotic-Related; Narcotic Abuses; Narcotic Addictions; Narcotic Related Disorders; Narcotic-Related Disorder; Narcotic Abuse; Narcotic Addiction; Narcotic Dependence

Networked: 206 relevant articles (8 outcomes, 15 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1.	Pain (Aches)
2.	Postoperative Pain
3.	Coma (Comas)
4.	Shock
5.	Psychotic Disorders (Schizoaffective Disorder)

Experts

1.	Bilsky, Edward J: 3 articles (05/2009 - 02/2004)
2.	Ahn, Junyoung: 2 articles (06/2016 - 01/2016)
3.	Bohl, Daniel D: 2 articles (06/2016 - 01/2016)
4.	Singh, Kern: 2 articles (06/2016 - 01/2016)
5.	Lu, Dominic P: 2 articles (10/2013 - 01/2004)
6.	Lu, Gabriel P: 2 articles (10/2013 - 01/2004)
7.	Sadée, Wolfgang: 2 articles (02/2005 - 02/2004)
8.	Wang, Danxin: 2 articles (02/2005 - 02/2004)
9.	Hammell, Dana C: 2 articles (06/2004 - 12/2002)
10.	Stinchcomb, Audra L: 2 articles (06/2004 - 12/2002)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Narcotic-Related Disorders:

1.	Methadone (Dolophine)FDA LinkGeneric 10/01/2000 - "Reviews issued by the Institute of Medicine and the National Institutes of Health have defined narcotic addiction as a chronic medical disorder and have claimed that methadone maintenance coupled with social services is the most effective treatment for this condition. " 01/01/1993 - "This hypothesis-generating study attempts to identify patient characteristics predicting the successful outcome of methadone maintenance in the treatment of narcotic addiction. " 01/01/1999 - "Access to narcotic addiction treatment and medical care: prospects for the expansion of methadone maintenance treatment." 12/01/1998 - "Methadone in the management of narcotic addiction in pregnancy." 05/01/1998 - "[Use of methadone in the treatment of narcotic addiction]."
2.	Morphine (MS Contin)FDA LinkGeneric 06/01/2001 - "To determine whether basal MOR signaling contributes to narcotic dependence, antagonists were tested for intrinsic effects on basal MOR signaling in vitro and in vivo, before and after morphine pretreatment. " 09/01/1983 - "These present findings suggest that the decrease in urinary excretion of sex-dependent LMWP is related to narcotic dependence in male rats, since we previously reported the decrease in urinary excreted LMWP in morphine-dependent rats." 02/01/1980 - "This weakening of endogenous regulation of 5HT neurons, which, however, still respond to acute morphine administration, might be part of the mechanism of compulsive drug use in narcotic addiction. " 01/01/1975 - "Perinatal narcotic addiction in mice: sensitization to morphine stimulation." 01/01/1975 - "Narcotic dependence in rats was established, in five days, by administering intravenous injections of morphine sulfate in increasing doses. "
3.	Opioid Analgesics (Opioids)IBA 02/01/2021 - "Research regarding the use of opioids in post sinus surgery over the past two years support previous thinking that there is an overprescription of opioids for an operation which is not particularly painful, resulting in the potential for narcotic abuse and misuse. " 12/01/2020 - "Given the increase in narcotic addiction and diversion, understanding how patients use their opioid prescriptions and store or dispose of any remainders is important. " 09/01/1987 - "Based on these findings we suggest that opioid-triggered release of inhibitory monocyte metabolites may play a role in the immunodeficiency associated with narcotic addiction and stress." 01/01/1986 - "In patients with maternal narcotic abuse during pregnancy, no opioid binding could be detected regardless of the mode of delivery, suggesting possible receptor down-regulation." 01/14/2020 - "The lack of therapeutics for optimal pain management is partially responsible for the current epidemic of opioid and narcotic abuse. "
4.	Narcotics (Narcotic Analgesics)IBA 11/01/1995 - "The purpose of this study was to identify an alternative method of initial narcotic abuse screening to distinguish members who have a greater likelihood of being correctly classified as potential narcotic abusers. " 09/01/2019 - "The national opioid epidemic exposes more parents to narcotic addiction in the community, which affects their perceptions of pediatric post-operative narcotic use. " 10/01/2018 - "Attempts to reduce the number of narcotic prescriptions are paramount in the fight against narcotic addiction in the United States. " 01/01/2016 - "Among patients who used narcotics preoperatively, no differences were demonstrated in terms of inpatient narcotic consumption (p = 0.182) or narcotic dependence following the first (p = 0.982) or second (p = 0.866) postoperative visit according to the self-reported accuracy of preoperative narcotic utilization. " 02/01/2012 - "Parental suspicions that the child may possibly take narcotics may be substantiated by hair analysis, which may not only identify the narcotic abuse profile, but also define the minimum period of narcotic usage. "
5.	Opiate AlkaloidsIBA 03/31/1975 - "In two cases of Guillain-Barré syndrome (acute polyneuritis) as a complication of narcotic abuse, the onset of paralysis began approximately 4 and 12 hours after self-administration of opiates intravenously. " 05/15/2009 - "The opiates 6beta-naltrexol and 6beta-naltrexamide function as neutral antagonists in in vitro and in vivo systems previously exposed to morphine, and are under investigation as improved treatments for narcotic dependence. " 04/01/2007 - "Adult male rhesus monkeys were treated with increasing doses of morphine for 90 d to induce opiate (narcotic) dependence. " 09/01/1996 - "[Opiate withdrawal in anesthesia (forced narcotic withdrawal, "turbo withdrawal") in narcotic dependence. " 04/01/1996 - "Patients with chronic pain and a history of narcotic abuse are not likely to develop addictions to opiates, and narcotics can be prescribed. "
6.	Narcotic Antagonists (Opioid Antagonists)IBA 01/01/1985 - "Implantable narcotic antagonists: a possible new treatment for narcotic addiction." 01/01/1978 - "A history of the development of narcotic antagonists for the treatment of narcotic addiction." 11/10/1976 - "These results suggest that the discriminative effects produced by morphine in the rat can provide an animal model for the quantitative evaluation of the narcotic antagonist properties of drugs that might be considered for use in narcotic antagonist maintenance programs for the treatment of narcotic addiction." 12/01/2002 - "Naltrexone (NTX) is an opioid antagonist used for treatment of narcotic dependence and alcoholism. "
7.	Insulin (Novolin)FDA Link 11/01/1957 - "Coma and psychosis following possible insulin hypersensitivity; with remission of narcotic addiction after severe hypoglycemic shock." 01/01/1984 - "In these subjects, it is possible to find increased concentrations of glycosylated hemoglobin A1 and a marked reduction of the acute insulin response to intravenous glucose, but not to arginine, which suggests a state of defective glucose recognition by pancreatic beta-cells during narcotic addiction. "
8.	Hypnotics and Sedatives (Sedatives)IBA 07/01/1979 - "A pharmacological view of narcotic addiction and alcoholism, or sedative addiction, serves as a basis for the further examination of these complex illnesses. " 01/01/2017 - "Evidence-based guidelines led to significant reduction in opioids and sedatives exposure, and in the number of infants requiring methadone for iatrogenic narcotic dependence."
9.	Hypoglycemic Agents (Hypoglycemics)IBA 11/01/1957 - "Coma and psychosis following possible insulin hypersensitivity; with remission of narcotic addiction after severe hypoglycemic shock."
10.	CyclazocineIBA 01/01/1974 - "A controlled study using cyclazocine in the treatment of narcotic addiction." 05/01/1968 - "Clinical studies of cyclazocine in the treatment of narcotic addiction." 09/01/1968 - "Basic concepts and use of cyclazocine in the treatment of narcotic addiction." 01/01/1967 - "Cyclazocine in the treatment of narcotic addiction." 06/01/1977 - "These results have important implications for drug abusers and for patients being treated for narcotic addiction with either a methadone maintenance program or a cyclazocine administration program."

Therapies and Procedures

1.	Activities of Daily Living (ADL) 10/01/2011 - "Fourteen of 16 patients had significant improvement of their pain, as evidenced by a decrease in subjectively reported postoperative pain levels as compared with their preoperative baseline, a decrease or complete elimination of daily narcotic dependence, and return to baseline activities of daily living and work. "
2.	Therapeutics 09/18/2015 - "Secondary outcomes included completion of adjuvant therapy, narcotic dependence, return to detrimental habits, loss of follow-up, and length of hospital stay (LOHS). " 04/01/1978 - "Moreover, the drug has potential for treating narcotic addiction since it is acceptable to addicts, is long-acting, produces a low level of physical dependence such that patients may be easily detoxified, is less toxic than drugs used for maintenance therapy, and blocks the effects of narcotics." 01/14/2020 - "The lack of therapeutics for optimal pain management is partially responsible for the current epidemic of opioid and narcotic abuse. " 01/01/1995 - "We introduce the term "virulent" Crohn's disease to describe those patients with most or all of the following: young age at onset, multiple surgical procedures, short bowel/malabsorption, chronic steroid therapy, narcotic addiction, and sepsis. " 01/01/1985 - "The highest predictive value with a high probability for staphylococcal etiology was recorded for combinations of the variables: i.v. narcotic addiction and septic pulmonary embolism; non-addiction, wound infection, and hospitalization within 4 weeks; non-addiction, absence of skin infection, presence of foreign body, and age less than 60 yr. Staphylococcal etiology was contradicted by the absence of i.v. narcotic addiction, skin infection, foreign body, septic skin manifestation, surgical procedure within 4 weeks, joint symptom and a C-reactive protein less than or equal to 10 mm. Thus, a prediction of etiology may be valuable in choosing therapy before definite confirmation by positive blood cultures or when blood cultures remain sterile."
3.	Drug Therapy (Chemotherapy) 01/01/1978 - "Recent developments in chemotherapy of narcotic addiction. " 01/01/1978 - "Recent developments in chemotherapy of narcotic addiction. " 01/01/1978 - "Recent developments in chemotherapy of narcotic addiction. " 01/01/1978 - "Recent developments in chemotherapy of narcotic addiction. " 01/01/1978 - "Recent developments in chemotherapy of narcotic addiction, 3-4 November 1977, Washington, D.C.: proceedings."
4.	Length of Stay 08/01/2022 - "The implications for widespread implementation of ERAS protocols during these procedures are a potentially shortened length of stay, expedited early return to function, reduction in narcotic dependence, and reduction in postdischarge complications necessitating additional intervention." 01/01/2008 - "Lower rates of blood loss, decreased narcotic dependence, and less tissue destruction as well as shorter hospital stays are all advantages of utilizing these techniques. " 09/18/2015 - "Secondary outcomes included completion of adjuvant therapy, narcotic dependence, return to detrimental habits, loss of follow-up, and length of hospital stay (LOHS). " 06/01/2016 - "Inpatient narcotic consumption, pain scores, nausea/vomiting, hospital length of stay, and narcotic dependence during the months after surgery were compared between MMA and PCA. "
5.	Pain Management 02/01/2018 - "An evidence-based approach to pain management can result in unchanged pain control and a significant positive impact on the narcotic abuse epidemic." 01/14/2020 - "The lack of therapeutics for optimal pain management is partially responsible for the current epidemic of opioid and narcotic abuse. " 10/01/2013 - "Acupuncture can be combined with conventional Western medicine for pain management in patient with cancer to reduce dosages of narcotic medications, side-effects, adverse reactions, and the possibility of narcotic addiction. "