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Guillan-Barré syndrome in heroin addiction.

Abstract
In two cases of Guillain-Barré syndrome (acute polyneuritis) as a complication of narcotic abuse, the onset of paralysis began approximately 4 and 12 hours after self-administration of opiates intravenously. Bulbar and respiratory paralysis developed in one patient and required prolonged ventilation therapy; the other patient had peripheral muscular and unilateral facial weakness, with notable pleocytosis was present in both.
AuthorsW R SMith, A F Wilson
JournalJAMA (JAMA) Vol. 231 Issue 13 Pg. 1367-8 (Mar 31 1975) ISSN: 0098-7484 [Print] United States
PMID1173082 (Publication Type: Journal Article)
Chemical References
  • Agglutinins
  • Heroin
Topics
  • Adolescent
  • Adult
  • Agglutinins (analysis)
  • Cerebrospinal Fluid (cytology)
  • Heroin (administration & dosage)
  • Heroin Dependence (complications)
  • Humans
  • Injections, Intravenous
  • Lymphocytes
  • Male
  • Muscular Diseases (chemically induced)
  • Polyradiculopathy (chemically induced, immunology)
  • Respiration, Artificial
  • Respiratory Paralysis (therapy)
  • Respiratory Tract Diseases (chemically induced)

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