Dipyridamole Drug Combination Aspirin

A drug combination of aspirin and dipyridamole that functions as a PLATELET AGGREGATION INHIBITOR, used to prevent THROMBOSIS and STROKE in TRANSIENT ISCHEMIC ATTACK patients.

Also Known As:

Aspirin, Dipyridamole Drug Combination; Aggrenox; Asasantin; Asasantin Retard; Aspirin-Dipyridamole Drug Combination; Extended-Release Dipyridamole-Aspirin; TX 3301; TX-3301; 3301, TX; Aspirin Dipyridamole Drug Combination; Combination, Aspirin-Dipyridamole Drug; Dipyridamole-Aspirin, Extended-Release; Drug Combination, Aspirin-Dipyridamole; Extended Release Dipyridamole Aspirin; Retard, Asasantin

Networked: 31 relevant articles (3 outcomes, 10 trials/studies)

Relationship Network

Drug Context: Research Results

Experts

1.	Hanley, Dan: 3 articles (01/2011 - 01/2006)
2.	Serebruany, Victor: 3 articles (01/2011 - 01/2006)
3.	Serebruany, Victor L: 3 articles (05/2006 - 04/2003)
4.	Benyamin, Ramsin M: 2 articles (04/2013 - 04/2013)
5.	Caraway, David L: 2 articles (04/2013 - 04/2013)
6.	Falco, Frank J E: 2 articles (04/2013 - 04/2013)
7.	Hansen, Hans: 2 articles (04/2013 - 04/2013)
8.	Helm, Standiford: 2 articles (04/2013 - 04/2013)
9.	Hirsch, Joshua A: 2 articles (04/2013 - 04/2013)
10.	Kaye, Alan D: 2 articles (04/2013 - 04/2013)

Related Diseases

1.	Stroke (Strokes) 05/01/2006 - "Therefore, Aggrenox should be considered a drug of choice to prevent the second stroke. " 01/01/2010 - "Aggrenox is used in the secondary prevention of stroke. " 01/01/2004 - "Aggrenox((R)) versus other pharmacotherapy in preventing recurrent stroke." 09/01/1999 - "Twice-daily oral extended-release dipyridamole/aspirin (400/50 mg/day) was twice as effective as either agent alone in the secondary prevention of stroke in a large clinical trial involving patients with prior stroke or transient ischaemic attack. " 05/01/2006 - "Should the PRoFESS (Prevention Regimen For Effectively avoiding Second Strokes) trial show an advantage in event reduction with Aggrenox over clopidogrel, the increase will be especially dramatic. "
2.	Headache (Headaches) 05/01/2006 - "Eliminating, or at least minimizing, the most frequent side effect, namely transitory headaches at the beginning of therapy with Aggrenox, will benefit patients and increase the use of this agent. " 09/28/2004 - "The authors assessed the prevalence of headaches following extended-release dipyridamole/aspirin combination (DAC), and the efficacy of acetaminophen in the treatment of these headaches. "
3.	Ischemia 09/01/2001 - "Aggrenox, a combination of low-dose aspirin and extended-release dipyridamole, is a new agent that is effective in the secondary prevention of stroke and transient ischemia of the brain. "
4.	Ischemic Stroke 03/01/2005 - "The authors sought to determine whether biological fluid pH is important for the serial measures of DIP levels in the animal experiments and in patients treated with Aggrenox after ischemic stroke. " 05/01/2006 - "In short, based on current evidence most guidelines include Aggrenox as a first-line option for secondary prevention of ischemic stroke or TIA, and some recent versions suggest it may be preferable in other clinical scenarios." 09/01/2009 - "Fifteen patients after documented ischaemic stroke were treated with Aggrenox (ERD and low-dose aspirin combination) BID for 30 days, and 12 of them completed the study. " 09/24/2004 - "Forty patients with prior ischemic stroke not taking aspirin for at least 30 days were randomized to Aggrenox (2 pills/daily) or aspirin (81 mg plus matching placebo/daily) for 30 days. " 09/24/2004 - "Magnitude and time course of platelet inhibition with Aggrenox and Aspirin in patients after ischemic stroke: the AGgrenox versus Aspirin Therapy Evaluation (AGATE) trial."
5.	Acute Kidney Injury (Acute Renal Failure) 01/01/2010 - "Acute renal failure, potentially associated with Aggrenox, has been observed in several patients. " 01/01/2010 - "A multi-case report of acute renal failure in patients treated with Aggrenox." 01/01/2010 - "The objective of this study was to determine if Aggrenox was associated with acute renal failure and to determine whether it was acetylsalicylic acid, dipyridamole or the combination that led to decline in renal function. "

Related Drugs and Biologics

1.	Aspirin (Acetylsalicylic Acid)
2.	Dipyridamole (Persantine)
3.	Acetaminophen (Paracetamol)
4.	Clopidogrel (Plavix)
5.	Platelet Aggregation Inhibitors (Antiplatelet Drugs)
6.	Dipyridamole Drug Combination Aspirin
7.	Phosphodiesterase Inhibitors
8.	Cilostazol (Pletal)
9.	Proton Pump Inhibitors
10.	Nitric Oxide Synthase Type III (Endothelial Nitric Oxide Synthase)

Related Therapies and Procedures

1.	Therapeutics
2.	Secondary Prevention
3.	Kidney Transplantation
4.	Drug Therapy (Chemotherapy)