HOME PRODUCTS COMPANY CONTACT FAQ

Research Dictionary Pharma

Sign Up FREE or Login

2- (2- (4- heptylphenyl)ethyl)- 6- hydroxy- benzoic acid

histone acetyltransferase inhibitor

Also Known As:

MG 149; MG-149; MG149

Networked: 9 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Chen, Xianxiong: 1 article (01/2022)
2.	Li, Huan: 1 article (01/2022)
3.	Liu, Shanshan: 1 article (01/2022)
4.	Lu, Desheng: 1 article (01/2022)
5.	Ning, Jiong: 1 article (01/2022)
6.	Sayed, Sapna: 1 article (01/2022)
7.	Su, Zijie: 1 article (01/2022)
8.	Sun, Qi: 1 article (01/2022)
9.	Tan, Lifeng: 1 article (01/2022)
10.	Tang, Yun: 1 article (01/2022)

Related Diseases

1.	Osteosarcoma (Osteogenic Sarcoma) 08/01/2023 - "Taken together, our results uncover Mof functioning as a novel regulator of osteoblast differentiation via the promotional effects on Runx2/Osterix and rationalize Mof as a potential therapeutic target, like possible application of inhibitor MG149 for the treatment of osteosarcoma or developing specific Mof activator to ameliorate osteoporosis."
2.	Respiratory Hypersensitivity 01/01/2021 - "MG149 inhibits histone acetyltransferase KAT8-mediated IL-33 acetylation to alleviate allergic airway inflammation and airway hyperresponsiveness."
3.	Pancreatic Neoplasms (Pancreatic Cancer) 01/01/2022 - "Furthermore, MG149, which was identified as a Tip60 inhibitor, significantly decreased the total Khib modification level in pancreatic cancer (PC) and strongly suppressed PC's proliferation, migration, and invasion ability. "
4.	Osteoporosis 08/01/2023 - "Taken together, our results uncover Mof functioning as a novel regulator of osteoblast differentiation via the promotional effects on Runx2/Osterix and rationalize Mof as a potential therapeutic target, like possible application of inhibitor MG149 for the treatment of osteosarcoma or developing specific Mof activator to ameliorate osteoporosis."
5.	Obesity 11/01/2021 - "Then we administrated mg149 to α-TC1-6 cell line, wild type, db/db and diet-induced obesity (DIO) mice to observe the impact of Mof inhibition in vitro and in vivo. "

Related Drugs and Biologics

1.	Histone Acetyltransferases (Histone Acetyltransferase)
2.	Catenins
3.	Interleukin-18 (Interleukin 18)
4.	Glutamic Acid (Glutamate)
5.	Sorafenib (BAY 43-9006)
6.	Interleukin-33