Chen Zhang Selected Research

Lung Neoplasms (Lung Cancer)

10/2023	FORMATION OF MALIGNANT, METASTATIC SMALL CELL LUNG CANCERS THROUGH OVERPRODUCTION OF cMYC PROTEIN IN TP53 AND RB1 DEPLETED PULMONARY NEUROENDOCRINE CELLS DERIVED FROM HUMAN EMBRYONIC STEM CELLS.
10/2023	TIMP1 is an early biomarker for detection and prognosis of lung cancer.
8/2023	Low‑dose anlotinib combined with EGFR‑TKI can be used as an alternative for EGFR‑TKI‑resistant non‑small cell lung cancer in elderly patients.
7/2023	Risks of cardiovascular toxicities associated with ALK tyrosine kinase inhibitors in patients with non-small-cell lung cancer: a meta-analysis of randomized control trials.
1/2023	Ponatinib: An update on its drug targets, therapeutic potential and safety.
1/2023	Carbonic Anhydrase IX Controls Vulnerability to Ferroptosis in Gefitinib-Resistant Lung Cancer.
1/2023	LncRNA LINC00969 promotes acquired gefitinib resistance by epigenetically suppressing of NLRP3 at transcriptional and posttranscriptional levels to inhibit pyroptosis in lung cancer.
1/2021	RNA methyltransferase METTL3 induces intrinsic resistance to gefitinib by combining with MET to regulate PI3K/AKT pathway in lung adenocarcinoma.
11/2020	Checkpoint inhibitor pneumonitis in Chinese lung cancer patients: clinical characteristics and risk factors.
1/2020	WDR74 induces nuclear β-catenin accumulation and activates Wnt-responsive genes to promote lung cancer growth and metastasis.

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Chen Zhang Research Topics

Disease

257	Neoplasms (Cancer) 05/2024 - 12/2004
100	Inflammation (Inflammations) 06/2024 - 04/2008
62	Schizophrenia (Dementia Praecox) 12/2023 - 10/2009
52	Infections 04/2024 - 11/2005
34	Alzheimer Disease (Alzheimer's Disease) 11/2023 - 03/2007
32	Hypoxia (Hypoxemia) 01/2024 - 07/2013
31	Wounds and Injuries (Trauma) 06/2024 - 04/2012
30	Neoplasm Metastasis (Metastasis) 03/2024 - 03/2009
29	Cognitive Dysfunction 01/2024 - 10/2002
25	Fibrosis (Cirrhosis) 04/2024 - 10/2010
25	Body Weight (Weight, Body) 04/2024 - 04/2013
24	Carcinogenesis 11/2023 - 03/2012
23	Major Depressive Disorder (Major Depressive Disorders) 05/2024 - 01/2013
22	Glioma (Gliomas) 11/2023 - 11/2014
22	Pain (Aches) 10/2023 - 01/2003
21	Hepatocellular Carcinoma (Hepatoma) 02/2024 - 08/2004
20	Obesity 12/2023 - 01/2013
19	Breast Neoplasms (Breast Cancer) 11/2023 - 05/2008
19	Psoriasis (Pustulosis Palmaris et Plantaris) 11/2023 - 01/2018
19	Hypertrophy 10/2023 - 05/2010
19	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 08/2023 - 01/2010
18	Necrosis 02/2024 - 05/2004
17	Colorectal Neoplasms (Colorectal Cancer) 04/2024 - 11/2015
17	Ulcerative Colitis 01/2024 - 01/2014
16	Pulmonary Arterial Hypertension 11/2023 - 07/2016
15	Heart Failure 05/2024 - 05/2013
15	Cardiovascular Diseases (Cardiovascular Disease) 05/2024 - 02/2011
15	Ovarian Neoplasms (Ovarian Cancer) 03/2024 - 12/2015
15	Lung Neoplasms (Lung Cancer) 10/2023 - 09/2016
14	COVID-19 04/2024 - 01/2020
14	Pneumocystis Pneumonia (Pneumocystis carinii Pneumonia) 10/2017 - 01/2006
13	Hypertension (High Blood Pressure) 05/2024 - 11/2008
13	Pulmonary Hypertension 10/2021 - 05/2010
12	Cardiomegaly (Heart Hypertrophy) 10/2023 - 04/2013
12	Lymphoma (Lymphomas) 07/2023 - 10/2011
12	Glioblastoma (Glioblastoma Multiforme) 12/2022 - 05/2015
12	Mitochondrial Diseases (Mitochondrial Disease) 01/2022 - 04/2014
12	Bipolar Disorder (Manic Depressive Psychosis) 01/2022 - 10/2013
11	Type 2 Diabetes Mellitus (MODY) 01/2024 - 01/2014
11	Colitis 12/2023 - 03/2020
11	Liver Neoplasms (Liver Cancer) 01/2023 - 09/2006
11	Atherosclerosis 01/2023 - 01/2013
10	Pneumonia (Pneumonitis) 05/2024 - 01/2006
10	Viremia 01/2024 - 12/2017
10	Stomach Neoplasms (Stomach Cancer) 01/2024 - 02/2017
10	Sepsis (Septicemia) 01/2024 - 12/2018
10	Carcinoma (Carcinomatosis) 12/2023 - 01/2014
10	Insulin Resistance 08/2023 - 04/2013
10	Epilepsy (Aura) 08/2022 - 01/2011

Drug/Important Bio-Agent (IBA)

133	Proteins (Proteins, Gene)FDA Link 04/2024 - 05/2003
69	Biomarkers (Surrogate Marker)IBA 05/2024 - 10/2010
50	CytokinesIBA 12/2023 - 10/2010
37	Therapeutic UsesIBA 02/2024 - 04/2013
35	Messenger RNA (mRNA)IBA 01/2023 - 12/2004
31	EnzymesIBA 12/2024 - 03/2010
29	MicroRNAs (MicroRNA)IBA 01/2024 - 01/2011
28	AntioxidantsIBA 02/2024 - 01/2015
25	Glucose (Dextrose)FDA LinkGeneric 05/2024 - 11/2011
23	LigandsIBA 09/2023 - 05/2017
22	HydrogelsIBA 06/2024 - 01/2018
21	Polysaccharides (Glycans)IBA 05/2024 - 11/2017
20	RNA (Ribonucleic Acid)IBA 05/2024 - 01/2012
20	DNA (Deoxyribonucleic Acid)IBA 05/2024 - 03/2012
20	Small Interfering RNA (siRNA)IBA 04/2024 - 07/2013
20	LipidsIBA 04/2024 - 09/2015
20	InflammasomesIBA 12/2023 - 03/2017
19	Brain-Derived Neurotrophic Factor (BDNF)IBA 05/2024 - 10/2011
19	Reactive Oxygen Species (Oxygen Radicals)IBA 12/2023 - 07/2016
18	AntigensIBA 07/2023 - 02/2014
18	Antipsychotic Agents (Antipsychotics)IBA 01/2021 - 05/2010
16	CollagenIBA 06/2024 - 04/2012
16	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 11/2023 - 03/2003
16	Phosphotransferases (Kinase)IBA 09/2023 - 04/2014
15	Anti-Bacterial Agents (Antibiotics)IBA 05/2024 - 09/2008
15	CateninsIBA 01/2024 - 06/2015
15	CholesterolIBA 01/2023 - 01/2013
15	Olanzapine (Zyprexa)FDA Link 01/2023 - 11/2014
14	Transcription Factors (Transcription Factor)IBA 02/2024 - 09/2016
14	Long Noncoding RNAIBA 12/2023 - 12/2015
14	ErbB Receptors (EGF Receptor)IBA 08/2023 - 01/2010
13	Oxygen (Dioxygen)IBA 11/2023 - 11/2011
12	Tyrosine Kinase InhibitorsIBA 01/2024 - 01/2017
12	Matrix Metalloproteinases (MMPs)IBA 01/2024 - 01/2010
12	Interleukin-6 (Interleukin 6)IBA 11/2023 - 04/2015
12	AcidsIBA 01/2023 - 09/2013
11	stachydrineIBA 04/2024 - 06/2012
11	1-phenyl-3,3-dimethyltriazene (PDT)IBA 01/2024 - 07/2015
11	Interleukin-17 (Interleukin 17)IBA 12/2023 - 03/2013
11	Caspase 3 (Caspase-3)IBA 11/2023 - 05/2008
10	ImmunosorbentsIBA 12/2024 - 10/2010
10	oxidized low density lipoproteinIBA 04/2024 - 01/2013
10	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2023 - 07/2010

Therapy/Procedure

148	Therapeutics 04/2024 - 01/2006
46	Drug Therapy (Chemotherapy) 05/2024 - 04/2011
21	Immunotherapy 03/2024 - 01/2019
16	Radiotherapy 02/2024 - 01/2010
13	Transplantation 12/2023 - 10/2002
11	Oral Administration 12/2023 - 01/2016
11	Lasers (Laser) 11/2023 - 04/2009
10	Photochemotherapy (Photodynamic Therapy) 01/2024 - 07/2015