Bernhards R Ogutu Selected Research

Falciparum Malaria (Plasmodium falciparum Malaria)

2/2022	Efficacy of 3-day low dose quinine plus clindamycin versus artemether-lumefantrine for the treatment of uncomplicated Plasmodium falciparum malaria in Kenyan children (CLINDAQUINE): an open-label randomized trial.
1/2022	Quinine plus clindamycin vs artemether-lumefantrine for treatment of uncomplicated falciparum malaria in western Kenya.
9/2015	Baseline data of parasite clearance in patients with falciparum malaria treated with an artemisinin derivative: an individual patient data meta-analysis.
3/2015	The effect of dosing strategies on the therapeutic efficacy of artesunate-amodiaquine for uncomplicated malaria: a meta-analysis of individual patient data.
1/2014	Efficacy and safety of artemether-lumefantrine and dihydroartemisinin-piperaquine in the treatment of uncomplicated Plasmodium falciparum malaria in Kenyan children aged less than five years: results of an open-label, randomized, single-centre study.
1/2009	Blood stage malaria vaccine eliciting high antigen-specific antibody concentrations confers no protection to young children in Western Kenya.
12/2008	A randomized, open-label, comparative efficacy trial of artemether-lumefantrine suspension versus artemether-lumefantrine tablets for treatment of uncomplicated Plasmodium falciparum malaria in children in western Kenya.
10/2008	Pharmacokinetics and clinical efficacy of midazolam in children with severe malaria and convulsions.
2/2007	Amodiaquine combined with sulfadoxine/pyrimethamine versus artemisinin-based combinations for the treatment of uncomplicated falciparum malaria in Africa: a meta-analysis.
11/2006	Safety and reactogenicity of an MSP-1 malaria vaccine candidate: a randomized phase Ib dose-escalation trial in Kenyan children.

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Bernhards R Ogutu Research Topics

Disease

25	Malaria 07/2023 - 12/2002
12	Falciparum Malaria (Plasmodium falciparum Malaria) 02/2022 - 07/2003
2	Reinfection 07/2023 - 03/2015
2	Infections 07/2023 - 01/2015
2	Glucosephosphate Dehydrogenase Deficiency 01/2018 - 01/2016
2	Seizures (Absence Seizure) 12/2013 - 07/2003
2	Status Epilepticus (Complex Partial Status Epilepticus) 10/2003 - 07/2003
1	Parasitemia 06/2022
1	Hemoglobinopathies 01/2018
1	Anemia 01/2016
1	Hemolytic Anemia 01/2016
1	Coinfection 01/2015
1	Neurologic Manifestations (Neurological Manifestations) 12/2013
1	Coma (Comas) 12/2013
1	Cerebral Malaria 01/2003

Drug/Important Bio-Agent (IBA)

9	artemisinin (artemisinine)IBA 07/2023 - 02/2007
6	Antimalarials (Antimalarial Agents)IBA 06/2022 - 06/2004
6	Lumefantrine Drug Combination Artemether (Coartem)FDA Link 02/2022 - 02/2007
4	ArtesunateIBA 01/2016 - 02/2007
4	Phenytoin (Dilantin)FDA LinkGeneric 12/2013 - 12/2002
3	artenimol (dihydroartemisinin)IBA 07/2023 - 01/2014
3	piperaquineIBA 07/2023 - 01/2014
3	TabletsIBA 02/2022 - 12/2008
3	Quinine (Quinson)FDA Link 02/2022 - 06/2004
3	VaccinesIBA 01/2018 - 11/2006
3	fosphenytoin (Cerebyx)FDA LinkGeneric 12/2013 - 12/2002
2	Chloroquine (Aralen)FDA LinkGeneric 06/2022 - 06/2004
2	Drug CombinationsIBA 02/2022 - 12/2021
2	Lumefantrine FDA Link 02/2022 - 12/2021
2	Artemether FDA Link 02/2022 - 12/2021
2	Clindamycin (Cleocin)FDA LinkGeneric 02/2022 - 01/2022
2	Amodiaquine (Camoquin)FDA Link 03/2015 - 02/2007
2	Malaria VaccinesIBA 04/2010 - 07/2009
2	Proteins (Proteins, Gene)FDA Link 01/2009 - 11/2006
2	Chloramphenicol (Chloromycetin)FDA Link 06/2004 - 12/2002
2	Phenobarbital (Luminal)FDA Link 06/2004 - 10/2003
1	18S Ribosomal RNAIBA 07/2023
1	Complement System Proteins (Complement)IBA 04/2020
1	Sickle HemoglobinIBA 01/2018
1	DNA (Deoxyribonucleic Acid)IBA 01/2017
1	ArtemisininsIBA 01/2017
1	Hemoglobins (Hemoglobin)IBA 01/2016
1	Stavudine (Zerit)FDA LinkGeneric 01/2015
1	Heroin (Diamorphine)IBA 01/2015
1	AntigensIBA 01/2009
1	Merozoite Surface Protein 1 (MSA1)IBA 01/2009
1	SuspensionsIBA 12/2008
1	Midazolam (Versed)FDA LinkGeneric 10/2008
1	Lorazepam (Ativan)FDA LinkGeneric 01/2008
1	pyrimethamine drug combination fanasil (Fansidar)FDA Link 02/2007
1	hemoglobin KenyaIBA 01/2007
1	Rabies Vaccines (Rabies Vaccine)FDA Link 11/2006
1	Gentamicins (Gentamicin)FDA LinkGeneric 06/2004
1	ParaldehydeIBA 06/2004
1	Penicillins (Penicillin)FDA Link 06/2004
1	Proguanil (Paludrine)FDA Link 06/2004
1	Pyrimethamine (Daraprim)FDA Link 06/2004
1	Anticonvulsants (Antiepileptic Drugs)IBA 06/2004
1	SalicylatesIBA 06/2004
1	Anti-Bacterial Agents (Antibiotics)IBA 06/2004
1	Sulfadoxine (Sulformethoxine)FDA Link 06/2004
1	Analgesics (Analgesic Drugs)IBA 06/2004
1	Acetaminophen (Paracetamol)FDA LinkGeneric 06/2004
1	cycloguanilIBA 06/2004
1	AntipyreticsIBA 06/2004
1	Diazepam (Valium)FDA LinkGeneric 06/2004
1	Oxygen (Dioxygen)IBA 07/2003
1	ProdrugsIBA 07/2003
1	Deferoxamine (Desferal)FDA LinkGeneric 01/2003
1	Adrenal Cortex Hormones (Corticosteroids)IBA 01/2003
1	Cefotaxime (Kendrick)FDA LinkGeneric 12/2002
1	chloramphenicol succinate FDA Link 12/2002

Therapy/Procedure

7	Therapeutics 07/2023 - 12/2010
1	Aftercare (After-Treatment) 03/2015
1	Intramuscular Injections 12/2013